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Publikationer som ChEBI hänvisar till för N(4)-hydroxycytidine. Visa hela publikationsregistret

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Publications in the selection

14 hits

Bibliografisk träff 2021-09-22

Ex vivo SARS-CoV-2 infection of human lung reveals heterogeneous host defense and therapeutic responses.

Schaller MA, Sharma Y, Dupee Z, Nguyen D, Urueña J, Smolchek R, Loeb JC, Machuca TN, Lednicky JA, Odde DJ, Campbell RF, Sawyer WG, Mehrad B.

JCI Insight · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1172/jci.insight.148003

Bibliografisk träff 2021-09-09

Remdesivir and EIDD-1931 Interact with Human Equilibrative Nucleoside Transporters 1 and 2: Implications for Reaching SARS-CoV-2 Viral Sanctuary Sites.

Miller SR, McGrath ME, Zorn KM, Ekins S, Wright SH, Cherrington NJ.

Mol Pharmacol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/molpharm.121.000333

Bibliografisk träff 2021-09-02

The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva.

Amara A, Penchala SD, Else L, Hale C, FitzGerald R, Walker L, Lyons R, Fletcher T, Khoo S.

J Pharm Biomed Anal · brief-report; journal article · DOI 10.1016/j.jpba.2021.114356

Bibliografisk träff 2021-08-11

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis.

Kabinger F, Stiller C, Schmitzová J, Dienemann C, Kokic G, Hillen HS, Höbartner C, Cramer P.

Nat Struct Mol Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41594-021-00651-0

Bibliografisk träff 2021-06-26

A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents.

Do TND, Donckers K, Vangeel L, Chatterjee AK, Gallay PA, Bobardt MD, Bilello JP, Cihlar T, De Jonghe S, Neyts J, Jochmans D.

Antiviral Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.antiviral.2021.105122

Bibliografisk träff 2021-05-11

Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template.

Gordon CJ, Tchesnokov EP, Schinazi RF, Götte M.

J Biol Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jbc.2021.100770

Bibliografisk träff 2021-03-31

Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors.

Langendries L, Abdelnabi R, Neyts J, Delang L.

Microorganisms · research-article; journal article · DOI 10.3390/microorganisms9040734

Bibliografisk träff 2021-03-01

Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2.

Painter WP, Holman W, Bush JA, Almazedi F, Malik H, Eraut NCJE, Morin MJ, Szewczyk LJ, Painter GR.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.02428-20

Bibliografisk träff 2021-01-01

An Updated Review on COVID-19.

Ebada MA, Wadaa-Allah A, Bahbah E, Negida A.

Infect Disord Drug Targets · review; journal article · DOI 10.2174/1871526520666201216165322

Bibliografisk träff 2020-12-01

Role of different tautomers in the base-pairing abilities of some of the vital antiviral drugs used against COVID-19.

Jena NR.

Phys Chem Chem Phys · journal article · DOI 10.1039/d0cp05297c

Bibliografisk träff 2020-04-06

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.

Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS.

Sci Transl Med · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1126/scitranslmed.abb5883

Bibliografisk träff 2019-11-26

Small-Molecule Antiviral β-d-<i>N</i><sup>4</sup>-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.

Agostini ML, Pruijssers AJ, Chappell JD, Gribble J, Lu X, Andres EL, Bluemling GR, Lockwood MA, Sheahan TP, Sims AC, Natchus MG, Saindane M, Kolykhalov AA, Painter GR, Baric RS, Denison MR.

J Virol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/jvi.01348-19

Bibliografisk träff 2019-10-01

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK.

Sci Transl Med · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1126/scitranslmed.aax5866

Bibliografisk träff 2019-09-05

The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection.

Painter GR, Bowen RA, Bluemling GR, DeBergh J, Edpuganti V, Gruddanti PR, Guthrie DB, Hager M, Kuiper DL, Lockwood MA, Mitchell DG, Natchus MG, Sticher ZM, Kolykhalov AA.

Antiviral Res · research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.antiviral.2019.104597