Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications.
Šebela M, Rašková M.
Molecules · review-article; review; journal article · DOI 10.3390/molecules28217429 PUBLICATION REGISTRY
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10 hitsThe uncharacterized Pseudomonas aeruginosa PA4189 is a novel and efficient aminoacetaldehyde dehydrogenase.
Fernández-Silva A, Juárez-Vázquez AL, González-Segura L, Juárez-Díaz JA, Muñoz-Clares RA.
Biochem J · research support, non-u.s. gov't; journal article · DOI 10.1042/bcj20220567The critical role of the aldehyde dehydrogenase PauC in spermine, spermidine, and diaminopropane toxicity in Pseudomonas aeruginosa: Its possible use as a drug target.
Cardona-Cardona YV, Regla I, Juárez-Díaz JA, Carrillo-Campos J, López-Ortiz M, Aguilera-Cruz A, Mújica-Jiménez C, Muñoz-Clares RA.
FEBS J · research support, non-u.s. gov't; journal article · DOI 10.1111/febs.16277NAD(+)-aminoaldehyde dehydrogenase candidates for 4-aminobutyrate (GABA) and β-alanine production during terminal oxidation of polyamines in apple fruit.
Zarei A, Trobacher CP, Shelp BJ.
FEBS Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.febslet.2015.08.005The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line.
Wood PL, Khan MA, Moskal JR.
Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.brainres.2006.10.004Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal.
Yu Z, Li W, Hillman J, Brunk UT.
Brain Res · comparative study; journal article · DOI 10.1016/j.brainres.2004.04.0753-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes.
Yu Z, Li W, Brunk UT.
APMIS · journal article · DOI 10.1034/j.1600-0463.2003.1110607.x3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin.
Li W, Yuan XM, Ivanova S, Tracey KJ, Eaton JW, Brunk UT.
Biochem J · research support, non-u.s. gov't; research-article; journal article · DOI 10.1042/bj20021520Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal.
Ivanova S, Batliwalla F, Mocco J, Kiss S, Huang J, Mack W, Coon A, Eaton JW, Al-Abed Y, Gregersen PK, Shohami E, Connolly ES, Tracey KJ.
Proc Natl Acad Sci U S A · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1073/pnas.082609299Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death.
Ivanova S, Botchkina GI, Al-Abed Y, Meistrell M, Batliwalla F, Dubinsky JM, Iadecola C, Wang H, Gregersen PK, Eaton JW, Tracey KJ.
J Exp Med · research-article; journal article · DOI 10.1084/jem.188.2.327