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Publikationer som ChEBI hänvisar till för AZ3451. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

7 hits

Bibliografisk träff 2021-09-30

Protease-Activated Receptor 2 (PAR-2) Antagonist AZ3451 Mitigates Oxidized Low-Density Lipoprotein (Ox-LDL)-Induced Damage and Endothelial Inflammation.

Sun L, Gai J, Shi S, Zhao J, Bai X, Liu B, Li X.

Chem Res Toxicol · journal article · DOI 10.1021/acs.chemrestox.1c00154

Bibliografisk träff 2021-07-15

Mutational analysis in international isolates and drug repurposing against SARS-CoV-2 spike protein: molecular docking and simulation approach.

Pulakuntla S, Lokhande KB, Padmavathi P, Pal M, Swamy KV, Sadasivam J, Singh SA, Aramgam SL, Reddy VD.

Virusdisease · research-article; journal article · DOI 10.1007/s13337-021-00720-4

Bibliografisk träff 2020-12-01

The development of proteinase-activated receptor-2 modulators and the challenges involved.

McIntosh KA, Cunningham MR, Bushell T, Plevin R.

Biochem Soc Trans · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1042/bst20200191

Bibliografisk träff 2019-12-16

Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.

Huang X, Ni B, Xi Y, Chu X, Zhang R, You H.

Aging (Albany NY) · research support, non-u.s. gov't; research-article; journal article · DOI 10.18632/aging.102586

Bibliografisk träff 2018-05-21

Isoxazole-tethered diarylheptanoid analogs: Discovery of a new drug-like PAR2 antagonist.

Bhuniya D, Bhosale S, Reddy SB, Reddy SN.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.05.032

Bibliografisk träff 2018-02-26

Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.

Lu S, Zhang J.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.7b01844

Bibliografisk träff 2017-04-26

Structural insight into allosteric modulation of protease-activated receptor 2.

Cheng RKY, Fiez-Vandal C, Schlenker O, Edman K, Aggeler B, Brown DG, Brown GA, Cooke RM, Dumelin CE, Doré AS, Geschwindner S, Grebner C, Hermansson NO, Jazayeri A, Johansson P, Leong L, Prihandoko R, Rappas M, Soutter H, Snijder A, Sundström L, Tehan B, Thornton P, Troast D, Wiggin G, Zhukov A, Marshall FH, Dekker N.

Nature · journal article · DOI 10.1038/nature22309