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Publikationer som ChEBI hänvisar till för C75. Visa hela publikationsregistret

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Publications in the selection

27 hits

Bibliografisk träff 2022-04-28

A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export.

Gomez-Martinez I, Bliton RJ, Breau KA, Czerwinski MJ, Williamson IA, Wen J, Rawls JF, Magness ST.

Cell Mol Gastroenterol Hepatol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jcmgh.2022.04.009

Bibliografisk träff 2021-12-21

A Multidrug Approach to Modulate the Mitochondrial Metabolism Impairment and Relative Oxidative Stress in Fanconi Anemia Complementation Group A.

Cappelli E, Bertola N, Bruno S, Degan P, Regis S, Corsolini F, Banelli B, Dufour C, Ravera S.

Metabolites · research-article; journal article · DOI 10.3390/metabo12010006

Bibliografisk träff 2021-08-17

The Emerging Role of Fatty Acid Synthase in Hypoxia-Induced Pulmonary Hypertensive Mouse Energy Metabolism.

Hou C, Chen J, Zhao Y, Niu Y, Lin S, Chen S, Zong Y, Sun X, Xie L, Xiao T.

Oxid Med Cell Longev · research-article; journal article · DOI 10.1155/2021/9990794

Bibliografisk träff 2020-06-29

Cytotoxicity and Radiosensitizing Activity of the Fatty Acid Synthase Inhibitor C75 Is Enhanced by Blocking Fatty Acid Uptake in Prostate Cancer Cells.

Rae C, Fragkoulis GI, Chalmers AJ.

Adv Radiat Oncol · research-article; journal article · DOI 10.1016/j.adro.2020.06.022

Bibliografisk träff 2016-11-30

Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75.

Rae C, Babich JW, Mairs RJ.

Chirality · brief-report; journal article · DOI 10.1002/chir.22668

Bibliografisk träff 2015-09-12

Inhibition of fatty acid synthase with C75 decreases organ injury after hemorrhagic shock.

Kuncewitch M, Yang WL, Jacob A, Khader A, Giangola M, Nicastro J, Coppa GF, Wang P.

Surgery · research-article; evaluation study; journal article; research support, n.i.h., extramural · DOI 10.1016/j.surg.2015.07.036

Bibliografisk träff 2014-05-01

4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function.

Chen C, Han X, Zou X, Li Y, Yang L, Cao K, Xu J, Long J, Liu J, Feng Z.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m114.550806

Bibliografisk träff 2014-01-17

Fatty acid synthase inhibitor C75 ameliorates experimental colitis.

Matsuo S, Yang WL, Aziz M, Kameoka S, Wang P.

Mol Med · research-article; journal article; research support, n.i.h., extramural · DOI 10.2119/molmed.2013.00113

Bibliografisk träff 2013-07-05

The central administration of C75, a fatty acid synthase inhibitor, activates sympathetic outflow and thermogenesis in interscapular brown adipose tissue.

Cassolla P, Uchoa ET, Mansur Machado FS, Guimarães JB, Rissato Garófalo MA, de Almeida Brito N, Kagohara Elias LL, Coimbra CC, do Carmo Kettelhut I, Carvalho Navegantes LC.

Pflugers Arch · research support, non-u.s. gov't; journal article · DOI 10.1007/s00424-013-1301-5

Bibliografisk träff 2013-05-01

Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.

Makowski K, Mera P, Paredes D, Herrero L, Ariza X, Asins G, Hegardt FG, García J, Serra D.

Chirality · research support, non-u.s. gov't; journal article · DOI 10.1002/chir.22139

Bibliografisk träff 2012-07-06

Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.

Relat J, Blancafort A, Oliveras G, Cufí S, Haro D, Marrero PF, Puig T.

BMC Cancer · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1471-2407-12-280

Bibliografisk träff 2012-06-02

Stimulation of carnitine palmitoyltransferase 1 improves renal function and attenuates tissue damage after ischemia/reperfusion.

Idrovo JP, Yang WL, Nicastro J, Coppa GF, Wang P.

J Surg Res · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jss.2012.05.053

Bibliografisk träff 2012-02-13

The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice.

Pellinen J, Szentirmai É.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0030651

Bibliografisk träff 2011-03-25

Diverse mechanisms of growth inhibition by luteolin, resveratrol, and quercetin in MIA PaCa-2 cells: a comparative glucose tracer study with the fatty acid synthase inhibitor C75.

Harris DM, Li L, Chen M, Lagunero FT, Go VL, Boros LG.

Metabolomics · research-article; journal article · DOI 10.1007/s11306-011-0300-9

Bibliografisk träff 2009-12-18

Striatal dopamine in the response of brain and liver unsaturated and saturated free fatty acids following administration of C75 in CD-1 mice.

Binienda ZK, Ross IA, Gough B, Riccio T, Kim CS, Ali SF.

Neurosci Lett · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2009.12.019

Bibliografisk träff 2008-12-01

Fatty acid synthase inhibitor, C75, blocks resistin-induced increases in lipid accumulation by human macrophages.

Rae C, Graham A.

Diabetes Obes Metab · letter; research support, non-u.s. gov't · DOI 10.1111/j.1463-1326.2008.00962.x

Bibliografisk träff 2008-11-27

C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.

Mera P, Bentebibel A, López-Viñas E, Cordente AG, Gurunathan C, Sebastián D, Vázquez I, Herrero L, Ariza X, Gómez-Puertas P, Asins G, Serra D, García J, Hegardt FG.

Biochem Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2008.11.020

Bibliografisk träff 2008-07-31

Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice.

Li LF, Lu YY, Xiong W, Liu JY, Chen Q.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2008.07.055

Bibliografisk träff 2008-07-30

Intraperitoneal injections of low doses of C75 elicit a behaviorally specific and vagal afferent-independent inhibition of eating in rats.

Mansouri A, Aja S, Moran TH, Ronnett G, Kuhajda FP, Arnold M, Geary N, Langhans W, Leonhardt M.

Am J Physiol Regul Integr Comp Physiol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajpregu.90381.2008

Bibliografisk träff 2006-04-01

Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.

Bentebibel A, Sebastián D, Herrero L, López-Viñas E, Serra D, Asins G, Gómez-Puertas P, Hegardt FG.

Biochemistry · research support, non-u.s. gov't; journal article · DOI 10.1021/bi052186q

Bibliografisk träff 2006-02-16

Intracerebroventricular C75 decreases meal frequency and reduces AgRP gene expression in rats.

Aja S, Bi S, Knipp SB, McFadden JM, Ronnett GV, Kuhajda FP, Moran TH.

Am J Physiol Regul Integr Comp Physiol · journal article; research support, n.i.h., extramural · DOI 10.1152/ajpregu.00041.2006

Bibliografisk träff 2005-09-16

The connections between C75 and obesity drug-target pathways.

Kuhajda FP, Landree LE, Ronnett GV.

Trends Pharmacol Sci · journal article · DOI 10.1016/j.tips.2005.09.002

Bibliografisk träff 2005-06-01

Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.

Rendina AR, Cheng D.

Biochem J · research-article; journal article · DOI 10.1042/bj20041963

Bibliografisk träff 2004-12-01

C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.

Nicot C, Napal L, Relat J, González S, Llebaria A, Woldegiorgis G, Marrero PF, Haro D.

Biochem Biophys Res Commun · comparative study; research support, non-u.s. gov't; evaluation study; journal article · DOI 10.1016/j.bbrc.2004.10.085

Bibliografisk träff 2003-11-13

C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism.

Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV.

J Biol Chem · journal article · DOI 10.1074/jbc.m310991200

Bibliografisk träff 2003-04-30

Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem.

Gao S, Lane MD.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.1031698100

Bibliografisk träff 2002-06-11

C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.

Thupari JN, Landree LE, Ronnett GV, Kuhajda FP.

Proc Natl Acad Sci U S A · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.132128899