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Publikationer som ChEBI hänvisar till för LY 379268. Visa hela publikationsregistret

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Publications in the selection

34 hits

Bibliografisk träff 2022-08-03

Meclizine and Metabotropic Glutamate Receptor Agonists Attenuate Severe Pain and Ca2+ Activity of Primary Sensory Neurons in Chemotherapy-Induced Peripheral Neuropathy.

Shannonhouse J, Bernabucci M, Gomez R, Son H, Zhang Y, Ai CH, Ishida H, Kim YS.

J Neurosci · research-article; journal article · DOI 10.1523/jneurosci.1064-21.2022

Bibliografisk träff 2021-08-17

Rescue of BDNF expression by the thalamic parafascicular nucleus with chronic treatment with the mGluR2/3 agonist LY379268 may contribute to the LY379268 rescue of enkephalinergic striatal projection neurons in R6/2 Huntington's disease mice.

Wang H, Del Mar N, Deng Y, Reiner A.

Neurosci Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neulet.2021.136180

Bibliografisk träff 2021-07-30

Metabotropic Glutamate Receptor 2/3 Activation Improves Motor Performance and Reduces Pathology in Heterozygous zQ175 Huntington Disease Mice.

Li SH, Colson TL, Abd-Elrahman KS, Ferguson SSG.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.121.000735

Bibliografisk träff 2021-03-06

Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains.

Bratek-Gerej E, Bronisz A, Ziembowicz A, Salinska E.

Oxid Med Cell Longev · research-article; journal article · DOI 10.1155/2021/8848015

Bibliografisk träff 2019-11-09

Effects of the mGluR2/3 receptor agonist LY379268 on the reinforcing strength of cocaine in rhesus monkeys.

Czoty PW, Blough BE, Landavazo A, Nader MA.

Psychopharmacology (Berl) · research-article; journal article · DOI 10.1007/s00213-019-05377-y

Bibliografisk träff 2019-10-03

The mGluR2/3 agonist LY379268 reverses NMDA receptor antagonist effects on cortical gamma oscillations and phase coherence, but not working memory impairments, in mice.

Sokolenko E, Hudson MR, Nithianantharajah J, Jones NC.

J Psychopharmacol · research support, non-u.s. gov't; journal article · DOI 10.1177/0269881119875976

Bibliografisk träff 2019-09-16

Unraveling the β-amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPα, and class-A scavenger receptor.

Durand D, Turati J, Rudi MJ, Ramírez D, Saba J, Caruso C, Carniglia L, von Bernhardi R, Lasaga M.

Neurochem Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuint.2019.104547

Bibliografisk träff 2019-07-12

Amygdala group II mGluRs mediate the inhibitory effects of systemic group II mGluR activation on behavior and spinal neurons in a rat model of arthritis pain.

Mazzitelli M, Neugebauer V.

Neuropharmacology · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuropharm.2019.107706

Bibliografisk träff 2019-01-01

LY379268 Does Not Have Long-Term Procognitive Effects nor Attenuate Glutamatergic Signaling in AβPP/PS1 Mice.

Hascup KN, Britz J, Findley CA, Tischkau S, Hascup ER.

J Alzheimers Dis · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.3233/jad-181231

Bibliografisk träff 2018-08-01

Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced conditioned place preference in rats.

Baharlouei N, Sarihi A, Moradi M, Zarrabian S, Haghparast A.

Behav Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/fbp.0000000000000375

Bibliografisk träff 2018-06-01

5-HT2A receptor-dependent phosphorylation of mGlu2 receptor at Serine 843 promotes mGlu2 receptor-operated Gi/o signaling.

Murat S, Bigot M, Chapron J, König GM, Kostenis E, Battaglia G, Nicoletti F, Bourinet E, Bockaert J, Marin P, Vandermoere F.

Mol Psychiatry · research support, non-u.s. gov't; journal article · DOI 10.1038/s41380-018-0069-6

Bibliografisk träff 2018-03-17

Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia.

Bratek E, Ziembowicz A, Salinska E.

Brain Sci · research-article; journal article · DOI 10.3390/brainsci8030048

Bibliografisk träff 2016-06-25

The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine.

Karkhanis AN, Beveridge TJ, Blough BE, Jones SR, Ferris MJ.

Drug Alcohol Depend · research-article; journal article · DOI 10.1016/j.drugalcdep.2016.06.020

Bibliografisk träff 2016-04-01

Erratum to: mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

Engel M, Snikeris P, Matosin N, Newell KA, Huang XF, Frank E.

Psychopharmacology (Berl) · published erratum · DOI 10.1007/s00213-016-4261-6

Bibliografisk träff 2016-02-10

mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

Engel M, Snikeris P, Matosin N, Newell KA, Huang XF, Frank E.

Psychopharmacology (Berl) · research support, non-u.s. gov't; journal article · DOI 10.1007/s00213-016-4230-0

Bibliografisk träff 2015-08-01

Nucleus accumbens injections of the mGluR2/3 agonist LY379268 increase cue-induced sucrose seeking following adult, but not adolescent sucrose self-administration.

Myal S, O'Donnell P, Counotte DS.

Neuroscience · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuroscience.2015.07.077

Bibliografisk träff 2015-07-08

Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.

Justinova Z, Le Foll B, Redhi GH, Markou A, Goldberg SR.

Psychopharmacology (Berl) · research support, n.i.h., intramural; research-article; journal article · DOI 10.1007/s00213-015-3994-y

Bibliografisk träff 2015-06-06

The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances.

Chan MH, Tsai YL, Lee MY, Stoker AK, Markou A, Chen HH.

Psychopharmacology (Berl) · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1007/s00213-015-3973-3

Bibliografisk träff 2014-07-22

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740.

Orlando R, Borro M, Motolese M, Molinaro G, Scaccianoce S, Caruso A, di Nuzzo L, Caraci F, Matrisciano F, Pittaluga A, Mairesse J, Simmaco M, Nisticò R, Monn JA, Nicoletti F, Nicoletti F.

Neuropharmacology · comparative study; journal article · DOI 10.1016/j.neuropharm.2014.07.009

Bibliografisk träff 2014-05-20

The metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats.

Pitsikas N, Markou A.

Neuropharmacology · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuropharm.2014.05.008

Bibliografisk träff 2014-03-11

The effect of ((-)-2-oxa-4-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY379268), an mGlu2/3 receptor agonist, on EEG power spectra and coherence in ketamine model of psychosis.

Fujáková M, Páleníček T, Brunovský M, Gorman I, Tylš F, Kubešová A, Řípová D, Krajča V, Horáček J.

Pharmacol Biochem Behav · research support, non-u.s. gov't; journal article · DOI 10.1016/j.pbb.2014.03.001

Bibliografisk träff 2014-01-01

Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry.

Benitex Y, Luan FN, Shields E, McNaney CA, Morgan DG, Olah TV, Drexler DM.

Bioanalysis · evaluation study; journal article · DOI 10.4155/bio.14.103

Bibliografisk träff 2013-11-19

The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex.

Menezes MM, Santini MA, Benvenga MJ, Marek GJ, Merchant KM, Mikkelsen JD, Svensson KA.

Neurosci J · research-article; journal article · DOI 10.1155/2013/736439

Bibliografisk träff 2013-08-12

The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu₂/₃ receptor agonist, LY379268, is 5-HT₁A dependent.

Wierońska JM, Sławińska A, Stachowicz K, Łasoń-Tyburkiewicz M, Gruca P, Papp M, Pilc A.

Behav Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbr.2013.08.007

Bibliografisk träff 2013-08-02

The group II metabotropic glutamate receptor agonist, LY379268, decreases methamphetamine self-administration in rats.

Crawford JT, Roberts DC, Beveridge TJ.

Drug Alcohol Depend · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.drugalcdep.2013.07.024

Bibliografisk träff 2013-07-01

Effects of group II and III metabotropic glutamate receptor ligands on conditioned taste aversion learning.

Klakotskaia D, Ramsey AK, Fowler SW, Serfozo P, Simonyi A, Schachtman TR.

Behav Brain Res · journal article · DOI 10.1016/j.bbr.2013.06.032

Bibliografisk träff 2013-06-11

The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety.

Grivas V, Markou A, Pitsikas N.

Eur J Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ejphar.2013.05.048

Bibliografisk träff 2013-04-29

The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.

Cannella N, Halbout B, Uhrig S, Evrard L, Corsi M, Corti C, Deroche-Gamonet V, Hansson AC, Spanagel R.

Neuropsychopharmacology · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/npp.2013.106

Bibliografisk träff 2013-04-12

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.

Wang MJ, Li YC, Snyder MA, Wang H, Li F, Gao WJ.

PLoS One · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0061787

Bibliografisk träff 2012-07-20

BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice.

Reiner A, Wang HB, Del Mar N, Sakata K, Yoo W, Deng YP.

Brain Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.brainres.2012.07.026

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Publications in the selection

Meclizine and Metabotropic Glutamate Receptor Agonists Attenuate Severe Pain and Ca<sup>2+</sup> Activity of Primary Sensory Neurons in Chemotherapy-Induced Peripheral Neuropathy.

Rescue of BDNF expression by the thalamic parafascicular nucleus with chronic treatment with the mGluR2/3 agonist LY379268 may contribute to the LY379268 rescue of enkephalinergic striatal projection neurons in R6/2 Huntington's disease mice.

Metabotropic Glutamate Receptor 2/3 Activation Improves Motor Performance and Reduces Pathology in Heterozygous zQ175 Huntington Disease Mice.

Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains.

Effects of the mGluR2/3 receptor agonist LY379268 on the reinforcing strength of cocaine in rhesus monkeys.

The mGluR<sub>2/3</sub> agonist LY379268 reverses NMDA receptor antagonist effects on cortical gamma oscillations and phase coherence, but not working memory impairments, in mice.

Unraveling the β-amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPα, and class-A scavenger receptor.

Amygdala group II mGluRs mediate the inhibitory effects of systemic group II mGluR activation on behavior and spinal neurons in a rat model of arthritis pain.

LY379268 Does Not Have Long-Term Procognitive Effects nor Attenuate Glutamatergic Signaling in AβPP/PS1 Mice.

Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced conditioned place preference in rats.

5-HT<sub>2A</sub> receptor-dependent phosphorylation of mGlu<sub>2</sub> receptor at Serine 843 promotes mGlu<sub>2</sub> receptor-operated G<sub>i/o</sub> signaling.

Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia.

The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine.

Erratum to: mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

Nucleus accumbens injections of the mGluR2/3 agonist LY379268 increase cue-induced sucrose seeking following adult, but not adolescent sucrose self-administration.

Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.

The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances.

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740.

The metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats.

The effect of ((-)-2-oxa-4-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY379268), an mGlu2/3 receptor agonist, on EEG power spectra and coherence in ketamine model of psychosis.

Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry.

The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex.

The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu₂/₃ receptor agonist, LY379268, is 5-HT₁A dependent.

The group II metabotropic glutamate receptor agonist, LY379268, decreases methamphetamine self-administration in rats.

Effects of group II and III metabotropic glutamate receptor ligands on conditioned taste aversion learning.

The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety.

The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.

BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice.