[Overexpression of human EP4 receptor in vascular smooth muscle cells attenuates angiotensin II-induced hypertension in mice].
Xu H, Wang SL, Bao CZ, Ye L, Guan YF, Zhang XY.
Sheng Li Xue Bao · journal article PUBLICATION REGISTRY
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11 hitsEP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia.
Ying F, Cai Y, Wong HK, Chen XY, Huang IB, Vanhoutte PM, Xia Z, Xu A, Tang EHC.
Biochim Biophys Acta Mol Cell Biol Lipids · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbalip.2018.06.003Role of the prostaglandin E2 receptor agonists in TGF-β1-induced mesangial cell damage.
Xi PP, Xu YY, Chen XL, Fan YP, Wu JH.
Biosci Rep · research-article; journal article · DOI 10.1042/bsr20160038The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway.
Olesen ET, Moeller HB, Assentoft M, MacAulay N, Fenton RA.
Am J Physiol Renal Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajprenal.00559.2015Therapeutic intervention of proanthocyanidins on the migration capacity of melanoma cells is mediated through PGE2 receptors and β-catenin signaling molecules.
Vaid M, Singh T, Prasad R, Kappes JC, Katiyar SK.
Am J Cancer Res · research-article; journal articleActivation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue.
Tang EH, Cai Y, Wong CK, Rocha VZ, Sukhova GK, Shimizu K, Xuan G, Vanhoutte PM, Libby P, Xu A.
J Lipid Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1194/jlr.m054817Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion.
Zheng H, Li Y, Wang Y, Zhao H, Zhang J, Chai H, Tang T, Yue J, Guo AM, Yang J.
Toxicol Appl Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.taap.2014.07.018Suppression of acute rejection by administration of prostaglandin E2 receptor subtype 4 agonist in rat organ transplantation models.
Okamoto T, Okamoto S, Fujimoto Y, Tabata Y, Uemoto S.
J Surg Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jss.2013.01.039Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition.
Singh T, Katiyar SK.
PLoS One · retracted publication; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0025224Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus.
Olesen ET, Olesen ET, Rützler MR, Moeller HB, Praetorius HA, Fenton RA.
Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.1104691108Discovery of a potent and selective agonist of the prostaglandin EP4 receptor.
Billot X, Chateauneuf A, Chauret N, Denis D, Greig G, Mathieu MC, Metters KM, Slipetz DM, Young RN.
Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(03)00042-8