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Publikationer som ChEBI hänvisar till för (-)-FR901483. Visa hela publikationsregistret

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Publications in the selection

24 hits

Bibliografisk träff 2023-12-05

Uncommon Arrangement of Self-resistance Allows Biosynthesis of de novo Purine Biosynthesis Inhibitor that Acts as an Immunosuppressor.

Sato M, Sakano S, Nakahara M, Tamura Y, Hara K, Hashimoto H, Tang Y, Watanabe K.

J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jacs.3c09600

Bibliografisk träff 2020-12-29

Biosynthesis of the Immunosuppressant (-)-FR901483.

Zhang Z, Tamura Y, Tang M, Qiao T, Sato M, Otsu Y, Sasamura S, Taniguchi M, Watanabe K, Tang Y.

J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jacs.0c12352

Bibliografisk träff 2019-12-30

Rapid Syntheses of (-)-FR901483 and (+)-TAN1251C Enabled by Complexity-Generating Photocatalytic Olefin Hydroaminoalkylation.

Reich D, Trowbridge A, Gaunt MJ.

Angew Chem Int Ed Engl · research support, non-u.s. gov't; journal article · DOI 10.1002/anie.201912010

Bibliografisk träff 2014-09-18

Atom transfer radical cyclization of trichloroacetamides to electron-rich acceptors using Grubbs' catalysts: synthesis of the tricyclic framework of FR901483.

Diaba F, Martínez-Laporta A, Bonjoch J.

J Org Chem · journal article · DOI 10.1021/jo501110c

Bibliografisk träff 2013-01-01

Enantioselective Synthesis of the Tricyclic Core of FR901483 Featuring a Rh-Catalyzed [2+2+2] Cycloaddition.

Perreault S, Rovis T.

Synthesis (Stuttg) · research-article; journal article · DOI 10.1055/s-0032-1316786

Bibliografisk träff 2012-12-18

Enantioselective total syntheses of (-)-FR901483 and (+)-8-epi-FR901483.

Huo HH, Xia XE, Zhang HK, Huang PQ.

J Org Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jo302362b

Bibliografisk träff 2012-08-31

A formal enantioselective total synthesis of FR901483.

Huo HH, Zhang HK, Xia XE, Huang PQ.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol302165d

Bibliografisk träff 2012-06-26

Total synthesis of (-)-FR901483.

Ma AJ, Tu YQ, Peng JB, Dou QY, Hou SH, Zhang FM, Wang SH.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol301331t

Bibliografisk träff 2012-05-02

Concise enantioselective construction of a bridged azatricyclic framework via domino semipinacol-Schmidt reaction.

Puppala M, Murali A, Baskaran S.

Chem Commun (Camb) · research support, non-u.s. gov't; journal article · DOI 10.1039/c2cc31906c

Bibliografisk träff 2009-02-01

Total synthesis of FR901483.

Carson CA, Kerr MA.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol802870c

Bibliografisk träff 2008-03-01

A Synthesis of the Tricyclic Core Structure of FR901483 Featuring an Ugi Four-Component Coupling and a Remarkably Selective Elimination Reaction.

Seike H, Sorensen EJ.

Synlett · research-article; journal article · DOI 10.1055/s-2008-1042813

Bibliografisk träff 2007-06-08

Toward the total synthesis of FR901483: concise synthesis of the azatricyclic skeleton.

Simila ST, Martin SF.

J Org Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jo070732a

Bibliografisk träff 2006-12-01

Synthetic studies toward (-)-FR901483 using a conjugate allylation to install the C-1 quaternary carbon.

Gotchev DB, Comins DL.

J Org Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/jo061677t

Bibliografisk träff 2006-10-01

Efficient approach to the Azaspirane core of FR 901483.

Kaden S, Reissig HU.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol061538y

Bibliografisk träff 2006-03-01

Studies on a total synthesis of the microbial immunosuppresive agent FR901483.

Kropf JE, Meigh IC, Bebbington MW, Weinreb SM.

J Org Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jo052466b

Bibliografisk träff 2005-02-01

A formal total synthesis of (-)-FR901483, using a tandem cationic aza-Cope rearrangement/Mannich cyclization approach.

Brummond KM, Hong SP.

J Org Chem · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jo0483567

Bibliografisk träff 2004-08-01

Stereocontrolled total synthesis of potent immunosuppressant FR901483.

Kan T, Fujimoto T, Ieda S, Asoh Y, Kitaoka H, Fukuyama T.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol049074w

Bibliografisk träff 2001-08-01

Total synthesis of tricyclic azaspirane derivatives of tyrosine: FR901483 and TAN1251C.

Ousmer M, Braun NA, Bavoux C, Perrin M, Ciufolini MA.

J Am Chem Soc · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/ja016030z

Bibliografisk träff 2001-05-01

Tandem cationic aza-cope rearrangement-Mannich cyclization approach to the core structure of FR901483 via a Bridgehead iminium ion.

Brummond KM, Lu J.

Org Lett · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/ol010029n

Bibliografisk träff 2001-04-01

Total synthesis of the immunosuppressant FR901483 via an amidoacrolein cycloaddition.

Maeng JH, Funk RL.

Org Lett · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/ol015506g

Bibliografisk träff 2001-03-01

Total synthesis of FR901483.

Ousmer M, Braun NA, Ciufolini MA.

Org Lett · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/ol015526i

Bibliografisk träff 2000-12-01

An Enantiospecific Synthesis of the Potent Immunosuppressant FR901483 Dr. G. Scheffler and H. Seike contributed equally to this work. We thank Dr. L. B. Pasternack and Dr. D. H. Huang for NMR spectroscopic assistance, and Dr. G. Siuzdak for mass spectrometric assistance. We also thank Dr. S. Takase and Dr. H. Setoi from the Fujisawa Pharmaceutical Co. for physical data for FR901483. This work was generously supported by The Skaggs Institute for Chemical Biology, a grant from the Merck Research Laboratories, a Beckman Young Investigator Award to E.J.S., and a predoctoral fellowship from the Heiwa Nakajima Foundation to H.S.

Scheffler G, Seike H, Sorensen EJ.

Angew Chem Int Ed Engl · journal article · DOI 10.1002/1521-3773(20001215)39:24<4593::aid-anie4593>3.0.co;2-x

Bibliografisk träff 1999-12-01

Synthesis and biological evaluation of a conformationally free seco-analogue of the immunosuppressant FR901483.

Bonjoch J, Diaba F, Puigbó G, Solé D, Segarra V, Santamaría L, Beleta J, Ryder H, Palacios JM.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/s0968-0896(99)00250-3

Bibliografisk träff 1996-01-01

FR901483, a novel immunosuppressant isolated from Cladobotryum sp. No. 11231. Taxonomy of the producing organism, fermentation, isolation, physico-chemical properties and biological activities.

Sakamoto K, Tsujii E, Abe F, Nakanishi T, Yamashita M, Shigematsu N, Izumi S, Okuhara M.

J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.49.37