Inhibition of autophagy by bafilomycin A1 promotes chemosensitivity of gastric cancer cells.
Li LQ, Xie WJ, Pan D, Chen H, Zhang L.
Tumour Biol · journal article · DOI 10.1007/s13277-015-3842-z PUBLICATION REGISTRY
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17 hitsBafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion.
Mauvezin C, Neufeld TP.
Autophagy · research-article; journal article · DOI 10.1080/15548627.2015.1066957Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia.
Yuan N, Song L, Zhang S, Lin W, Cao Y, Xu F, Fang Y, Wang Z, Zhang H, Li X, Wang Z, Cai J, Wang J, Zhang Y, Mao X, Zhao W, Hu S, Chen S, Wang J.
Haematologica · research support, non-u.s. gov't; research-article; journal article · DOI 10.3324/haematol.2014.113324Phagocytosis of bafilomycin A1-treated apoptotic neuroblastoma cells by bone marrow-derived dendritic cells initiates a CD8α+ lymphocyte response to neuroblastoma.
Inoue S, Setoyama Y, Odaka A.
J Pediatr Hematol Oncol · research support, non-u.s. gov't; journal article · DOI 10.1097/mph.0000000000000060Bafilomycin A1 inhibits autophagy and induces apoptosis in MG63 osteosarcoma cells.
Xie Z, Xie Y, Xu Y, Zhou H, Xu W, Dong Q.
Mol Med Rep · research support, non-u.s. gov't; journal article · DOI 10.3892/mmr.2014.2281Bafilomycin A1 and its attenuating effect on tumour growth in systemic malignancies, especially gastrointestinal malignancies.
Kapoor S.
Clin Sci (Lond) · letter; comment · DOI 10.1042/cs20130057Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling.
Zhdanov AV, Dmitriev RI, Papkovsky DB.
Biosci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1042/bsr20120085Total synthesis of bafilomycin A1.
Kleinbeck F, Fettes GJ, Fader LD, Carreira EM.
Chemistry · research support, non-u.s. gov't; journal article · DOI 10.1002/chem.201102797Increased production of reactive oxygen species by the vacuolar-type (H(+))-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells.
Yokomakura A, Hong J, Ohuchi K, Oh SE, Lee JY, Mano N, Takahashi T, Hwang GW, Naganuma A.
J Toxicol Sci · journal article · DOI 10.2131/jts.37.1045Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria.
Zhdanov AV, Dmitriev RI, Papkovsky DB.
Cell Mol Life Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s00018-010-0502-8Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells.
Wu YC, Wu WK, Li Y, Yu L, Li ZJ, Wong CC, Li HT, Sung JJ, Cho CH.
Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2009.03.051Total synthesis of bafilomycin A1.
Kleinbeck F, Carreira EM.
Angew Chem Int Ed Engl · research support, non-u.s. gov't; journal article · DOI 10.1002/anie.200804645Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions.
Teplova VV, Tonshin AA, Grigoriev PA, Saris NE, Salkinoja-Salonen MS.
J Bioenerg Biomembr · research support, non-u.s. gov't; journal article · DOI 10.1007/s10863-007-9095-9Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins.
Tollefson AE, Toth K, Doronin K, Kuppuswamy M, Doronina OA, Lichtenstein DL, Hermiston TW, Smith CA, Wold WS.
J Virol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1128/jvi.75.19.8875-8887.2001Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase.
Gagliardi S, Rees M, Farina C.
Curr Med Chem · review; journal articleBafilomycin A1 inhibits bone resorption and tooth eruption in vivo.
Sundquist KT, Marks SC.
J Bone Miner Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1002/jbmr.5650091010Bafilomycin A1 inhibits Helicobacter pylori-induced vacuolization of HeLa cells.
Papini E, Bugnoli M, De Bernard M, Figura N, Rappuoli R, Montecucco C.
Mol Microbiol · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1365-2958.1993.tb01123.x