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Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för THZ1. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

7 hits

Bibliografisk träff 2024-07-01

Inhibition of cyclin-dependent kinase 7 mitigates doxorubicin cardiotoxicity and enhances anticancer efficacy.

Chen J, Wei J, Xia P, Liu Y, Belew MD, Toohill R, Wu BJ, Cheng Z.

Cardiovasc Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/cvr/cvae084

Bibliografisk träff 2024-01-09

Co-overexpression of BRD4 and CDK7 promotes cell proliferation and predicts poor prognosis in HCC.

Li X, Zheng C, Liu Y, Sun H, Qian Y, Fan H.

Heliyon · research-article; journal article · DOI 10.1016/j.heliyon.2024.e24389

Bibliografisk träff 2023-12-01

The suppressive efficacy of THZ1 depends on KRAS mutation subtype and is associated with super-enhancer activity and the PI3K/AKT/mTOR signalling in pancreatic ductal adenocarcinoma: A hypothesis-generating study.

Huang L, Yang H, Chen K, Yuan J, Li J, Dai G, Gu M, Shi Y.

Clin Transl Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/ctm2.1500

Bibliografisk träff 2023-08-01

Effect of CDK7 inhibitor on MYCN-amplified retinoblastoma.

Xu H, Xiao L, Chen Y, Liu Y, Zhang Y, Gao Y, Man S, Yan N, Zhang M.

Biochim Biophys Acta Gene Regul Mech · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbagrm.2023.194964

Bibliografisk träff 2023-06-25

Targeting transcriptional kinase of CDK7 halts proliferation of multiple myeloma cells by modulating the function of canonical NF-kB pathway and cell cycle regulatory proteins.

Dutta RP, Kumar R, Tembhare PR, Bagal B, Swain RK, Hasan SK.

Transl Oncol · research-article; journal article · DOI 10.1016/j.tranon.2023.101729

Bibliografisk träff 2023-05-05

Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.

van der Noord VE, van der Stel W, Louwerens G, Verhoeven D, Kuiken HJ, Lieftink C, Grandits M, Ecker GF, Beijersbergen RL, Bouwman P, Le Dévédec SE, van de Water B.

Breast Cancer Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s13058-023-01648-x

Bibliografisk träff 2015-06-06

Cyclin dependent kinase (CDK) inhibitors as anticancer drugs.

Sánchez-Martínez C, Gelbert LM, Lallena MJ, de Dios A.

Bioorg Med Chem Lett · review; journal article · DOI 10.1016/j.bmcl.2015.05.100