PUBLICATION REGISTRY

Go to research.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för AM6545. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

25 hits

Bibliografisk träff 2024-05-15

Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.

Wood CP, Alvarez C, DiPatrizio NV.

J Neurosci · research-article; journal article; research support, n.i.h., extramural · DOI 10.1523/jneurosci.0813-23.2024

Bibliografisk träff 2024-02-19

Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26, 866.

Eid BG, Neamatallah T, Hanafy A, El-Bassossy HM, Binmahfouz L, Aldawsari HM, Hasan A, Abd El-Aziz G, Vemuri K, Makriyannis A.

Molecules · published erratum; correction · DOI 10.3390/molecules29040902

Bibliografisk träff 2023-11-03

Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats.

Eid BG, Neamatallah T, Binmahfouz LS, Bagher AM, Alamoudi AJ, Aldawsari HM, Hanafy A, Hasan A, El-Bassossy HM, Abdel-Naim AB, Vemuri K, Makriyannis A.

Biomol Biomed · research-article; journal article · DOI 10.17305/bb.2023.9173

Bibliografisk träff 2023-10-29

Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201.

AlKhelb D, Burke EL, Zvonok A, Iliopoulos-Tsoutsouvas C, Georgiadis MO, Jiang S, Ho TC, Nikas SP, Makriyannis A, Desai RI.

Eur J Pharmacol · research-article; journal article · DOI 10.1016/j.ejphar.2023.176168

Bibliografisk träff 2023-01-20

The cannabinoid receptor 1 antagonist AM6545 stimulates the Akt-mTOR axis and in vivo muscle protein synthesis in a dexamethasone-induced muscle atrophy model.

Dalle S, Schouten M, Ramaekers M, Koppo K.

Mol Cell Endocrinol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.mce.2023.111854

Bibliografisk träff 2022-09-10

Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism.

Martínez-Torres S, Bergadà-Martínez A, Ortega JE, Galera-López L, Hervera A, de Los Reyes-Ramírez L, Ortega-Álvaro A, Remmers F, Muñoz-Moreno E, Soria G, Del Río JA, Lutz B, Ruíz-Ortega JÁ, Meana JJ, Maldonado R, Ozaita A.

Neuropsychopharmacology · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41386-022-01436-9

Bibliografisk träff 2022-07-05

Role of CB1 receptors in the acute regulation of small intestinal permeability: effects of high-fat diet.

Cuddihey H, Cavin JB, Keenan CM, Wallace LE, Vemuri K, Makriyannis A, MacNaughton WK, Sharkey KA.

Am J Physiol Gastrointest Liver Physiol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajpgi.00341.2021

Bibliografisk träff 2021-04-08

Cannabinoid Receptor Subtype-1 Regulates Allergic Airway Eosinophilia During Lung Helminth Infection.

Wiley MB, Bobardt SD, Nordgren TM, Nair MG, DiPatrizio NV.

Cannabis Cannabinoid Res · research-article; journal article; research support, n.i.h., extramural · DOI 10.1089/can.2020.0167

Bibliografisk träff 2021-02-06

Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome.

Eid BG, Neamatallah T, Hanafy A, El-Bassossy HM, Binmahfouz L, Aldawsari HM, Hasan A, El-Aziz GA, Vemuri K, Makriyannis A.

Molecules · research-article; journal article · DOI 10.3390/molecules26040866

Bibliografisk träff 2020-11-20

Peripherally restricted cannabinoid type 1 receptor (CB1R) antagonist, AM6545, potentiates stress-induced hypothalamic-pituitary-adrenal axis activation via a non-CB1R mechanism.

Roberts CJ, Hillard CJ.

Endocrine · letter; research support, non-u.s. gov't; research-article; research support, n.i.h., extramural · DOI 10.1007/s12020-020-02549-1

Bibliografisk träff 2020-10-29

Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome.

Eid BG, Neamatallah T, Hanafy A, El-Bassossy HM, Aldawsari HM, Vemuri K, Makriyannis A.

Medicina (Kaunas) · research-article; journal article · DOI 10.3390/medicina56110573

Bibliografisk träff 2020-09-26

Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARα dependent.

Azar S, Udi S, Drori A, Hadar R, Nemirovski A, Vemuri KV, Miller M, Sherill-Rofe D, Arad Y, Gur-Wahnon D, Li X, Makriyannis A, Ben-Zvi D, Tabach Y, Ben-Dov IZ, Tam J.

Mol Metab · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.molmet.2020.101087

Bibliografisk träff 2020-09-10

A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided.

Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms21186639

Bibliografisk träff 2020-01-01

Involvement of cannabinoid type 1 receptor in fasting-induced analgesia.

Lee JY, Lee GJ, Nakamura A, Lee PR, Kim Y, Won CH, Furue H, Oh SB.

Mol Pain · research support, non-u.s. gov't; research-article; journal article · DOI 10.1177/1744806920969476

Bibliografisk träff 2019-06-11

Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity.

Argueta DA, Perez PA, Makriyannis A, DiPatrizio NV.

Front Physiol · research-article; journal article · DOI 10.3389/fphys.2019.00704

Bibliografisk träff 2018-11-06

Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.

Barutta F, Bellini S, Mastrocola R, Gambino R, Piscitelli F, di Marzo V, Corbetta B, Vemuri VK, Makriyannis A, Annaratone L, Bruno G, Gruden G.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.14495

Bibliografisk träff 2018-03-20

Peripheral CB1 Receptor Neutral Antagonist, AM6545, Ameliorates Hypometabolic Obesity and Improves Adipokine Secretion in Monosodium Glutamate Induced Obese Mice.

Ma H, Zhang G, Mou C, Fu X, Chen Y.

Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2018.00156

Bibliografisk träff 2017-10-01

Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy.

Barutta F, Grimaldi S, Gambino R, Vemuri K, Makriyannis A, Annaratone L, di Marzo V, Bruno G, Gruden G.

Nephrol Dial Transplant · journal article · DOI 10.1093/ndt/gfx010

Bibliografisk träff 2017-02-01

Differential effects of cannabinoid CB1 inverse agonists and antagonists on impulsivity in male Sprague Dawley rats: identification of a possibly clinically relevant vulnerability involving the serotonin 5HT1A receptor.

McLaughlin PJ, Jagielo-Miller JE, Plyler ES, Schutte KK, Vemuri VK, Makriyannis A.

Psychopharmacology (Berl) · journal article · DOI 10.1007/s00213-017-4548-2

Bibliografisk träff 2015-10-01

Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1.

Bronova I, Smith B, Aydogan B, Weichselbaum RR, Vemuri K, Erdelyi K, Makriyannis A, Pacher P, Berdyshev EV.

Am J Respir Cell Mol Biol · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1165/rcmb.2014-0331oc

Bibliografisk träff 2015-03-15

Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist.

Tai S, Nikas SP, Shukla VG, Vemuri K, Makriyannis A, Järbe TU.

Psychopharmacology (Berl) · research-article; journal article; research support, n.i.h., extramural · DOI 10.1007/s00213-015-3907-0

Bibliografisk träff 2013-07-04

Peripherally restricted CB1 receptor blockers.

Chorvat RJ.

Bioorg Med Chem Lett · review; journal article · DOI 10.1016/j.bmcl.2013.06.066

Bibliografisk träff 2010-10-01

A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents.

Cluny NL, Vemuri VK, Chambers AP, Limebeer CL, Bedard H, Wood JT, Lutz B, Zimmer A, Parker LA, Makriyannis A, Sharkey KA.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/j.1476-5381.2010.00908.x

Bibliografisk träff 2010-08-14

The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior.

Randall PA, Vemuri VK, Segovia KN, Torres EF, Hosmer S, Nunes EJ, Santerre JL, Makriyannis A, Salamone JD.

Pharmacol Biochem Behav · comparative study; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.pbb.2010.07.021

Bibliografisk träff 2010-07-26

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.

Tam J, Vemuri VK, Liu J, Bátkai S, Mukhopadhyay B, Godlewski G, Osei-Hyiaman D, Ohnuma S, Ambudkar SV, Pickel J, Makriyannis A, Kunos G.

J Clin Invest · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1172/jci42551

Go to research.

Publications in the selection

Cholinergic Neurotransmission Controls Orexigenic Endocannabinoid Signaling in the Gut in Diet-Induced Obesity.

Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. <i>Molecules</i> 2021, <i>26</i>, 866.

Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats.

Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201.

The cannabinoid receptor 1 antagonist AM6545 stimulates the Akt-mTOR axis and in vivo muscle protein synthesis in a dexamethasone-induced muscle atrophy model.

Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism.

Role of CB<sub>1</sub> receptors in the acute regulation of small intestinal permeability: effects of high-fat diet.

Cannabinoid Receptor Subtype-1 Regulates Allergic Airway Eosinophilia During Lung Helminth Infection.

Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome.

Peripherally restricted cannabinoid type 1 receptor (CB1R) antagonist, AM6545, potentiates stress-induced hypothalamic-pituitary-adrenal axis activation via a non-CB1R mechanism.

Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome.

Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARα dependent.

A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided.

Involvement of cannabinoid type 1 receptor in fasting-induced analgesia.

Cannabinoid CB<sub>1</sub> Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity.

Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.

Peripheral CB1 Receptor Neutral Antagonist, AM6545, Ameliorates Hypometabolic Obesity and Improves Adipokine Secretion in Monosodium Glutamate Induced Obese Mice.

Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy.

Differential effects of cannabinoid CB1 inverse agonists and antagonists on impulsivity in male Sprague Dawley rats: identification of a possibly clinically relevant vulnerability involving the serotonin 5HT<sub>1A</sub> receptor.

Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1.

Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist.

Peripherally restricted CB1 receptor blockers.

A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents.

The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior.

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.