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Publikationer som ChEBI hänvisar till för BAM15. Visa hela publikationsregistret

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Publications in the selection

27 hits

Bibliografisk träff 2024-12-18

Unsymmetric hydroxylamine and hydrazine BAM15 derivatives as potent mitochondrial uncouplers.

Quinlan JE, Salamoun JM, Garcia CJ, Hargett S, Beretta M, Shrestha R, Li C, Hoehn KL, Santos WL.

Bioorg Med Chem · research-article; journal article · DOI 10.1016/j.bmc.2024.118045

Bibliografisk träff 2024-11-30

Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4-b]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Associated Steatohepatitis.

Foutz MA, Krinos EL, Beretta M, Hargett SR, Shrestha R, Murray JH, Duerre E, Salamoun JM, McCarter K, Shah DP, Hoehn KL, Santos WL.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.4c02366

Bibliografisk träff 2024-11-16

ATP Restoration by ATP-Deprived Cultured Primary Astrocytes.

Karger G, Willker JE, Harders AR, Watermann P, Dringen R.

Neurochem Res · research-article; journal article · DOI 10.1007/s11064-024-04276-9

Bibliografisk träff 2024-11-12

Correction to "Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease".

Författaruppgift saknas

Acta Physiol (Oxf) · published erratum · DOI 10.1111/apha.14250

Bibliografisk träff 2024-10-05

Design, synthesis, and biological evaluation of imidazo[4,5-b]pyridine mitochondrial uncouplers for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

Salamoun JM, Krinos EL, Foutz MA, Hargett SR, Beretta M, Shrestha R, Hoehn KL, Santos WL.

Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2024.116916

Bibliografisk träff 2024-08-20

Mitochondrial uncoupling caused by a wide variety of protonophores is differently sensitive to carboxyatractyloside in rat heart and liver mitochondria.

Khailova LS, Kirsanov RS, Rokitskaya TI, Krasnov VS, Korshunova GA, Kotova EA, Antonenko YN.

Biochim Biophys Acta Bioenerg · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbabio.2024.149506

Bibliografisk träff 2024-08-16

Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease.

Zhou M, Li C, Byrne FL, Vancuylenburg CS, Olzomer EM, Hargreaves A, Wu LE, Shackel NA, Santos WL, Hoehn KL.

Acta Physiol (Oxf) · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/apha.14217

Bibliografisk träff 2024-05-10

Characterization of an in vitro model to study CD4+ T cell metabolism in dairy cows.

Arshad U, Cid de la Paz M, White HM, Cangiano LR.

JDS Commun · brief-report; journal article · DOI 10.3168/jdsc.2024-0565

Bibliografisk träff 2024-03-01

Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice.

Beretta M, Dai Y, Olzomer EM, Vancuylenburg CS, Santiago-Rivera JA, Philp AM, Hargett SR, Li K, Shah DP, Chen SY, Alexopoulos SJ, Li C, Harris TE, Lee B, Wathier M, Cermak JM, Tucker SP, Turner N, Bayliss DA, Philp A, Byrne FL, Santos WL, Hoehn KL.

Diabetes · research-article; journal article · DOI 10.2337/db23-0233

Bibliografisk träff 2024-03-01

Effect of the mitochondrial uncoupling agent BAM15 against the Toxoplasma gondii RH strain and Prugniaud strain.

Liu Z, Mo J, Li Y, Liu S, Zeng Q, Zhang J.

Parasit Vectors · research-article; journal article · DOI 10.1186/s13071-024-06187-8

Bibliografisk träff 2024-02-11

Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster.

Taylor AL, Dubuisson O, Pandey P, Zunica ERM, Vandanmagsar B, Dantas WS, Johnson A, Axelrod CL, Kirwan JP.

Aging Cell · research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/acel.14107

Bibliografisk träff 2024-02-01

Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice.

Chen SY, Telfser AJ, Olzomer EM, Vancuylenberg CS, Zhou M, Beretta M, Li C, Alexopoulos SJ, Turner N, Byrne FL, Santos WL, Hoehn KL.

Clin Sci (Lond) · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1042/cs20231016

Bibliografisk träff 2023-11-28

Polymeric Particle BAM15 Targeting Macrophages Attenuates the Severity of LPS-Induced Sepsis: A Proof of Concept for Specific Immune Cell-Targeted Therapy.

Udompornpitak K, Bhunyakarnjanarat T, Saisorn W, Manipuntee C, Plengplang K, Sittichaitaweekul S, Jenphatanapong P, Udomkarnjananun S, Kaewduangduen W, Ariya-Anandech K, Samaeng A, Insin N, Ritprajak P, Leelahavanichkul A.

Pharmaceutics · research-article; journal article · DOI 10.3390/pharmaceutics15122695

Bibliografisk träff 2023-10-11

BAM15 as a mitochondrial uncoupler: a promising therapeutic agent for diverse diseases.

Xiong G, Zhang K, Ma Y, Song Y, Zhang W, Qi T, Qiu H, Shi J, Kan C, Zhang J, Sun X.

Front Endocrinol (Lausanne) · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.3389/fendo.2023.1252141

Bibliografisk träff 2023-10-02

Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice.

Chen SY, Beretta M, Olzomer EM, Alexopoulos SJ, Shah DP, Byrne FL, Salamoun JM, Garcia CJ, Smith GC, Larance M, Philp A, Turner N, Santos WL, Cantley J, Hoehn KL.

Biochim Biophys Acta Mol Basis Dis · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbadis.2023.166908

Bibliografisk träff 2023-04-03

BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils.

Tsuji N, Tsuji T, Yamashita T, Hayase N, Hu X, Yuen PS, Star RA.

J Clin Invest · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article · DOI 10.1172/jci152401

Bibliografisk träff 2023-03-14

Endogenous Energy Stores Maintain a High ATP Concentration for Hours in Glucose-Depleted Cultured Primary Rat Astrocytes.

Harders AR, Arend C, Denieffe SC, Berger J, Dringen R.

Neurochem Res · research-article; journal article · DOI 10.1007/s11064-023-03903-1

Bibliografisk träff 2022-11-17

BAM15 Relieves Neurodegeneration in Aged Caenorhabditis elegans and Extends Lifespan.

Cho I, Song HO, Ji HE, Yang S, Cho JH.

Metabolites · research-article; journal article · DOI 10.3390/metabo12111129

Bibliografisk träff 2022-05-13

Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice.

Hiengrach P, Visitchanakun P, Tongchairawewat P, Tangsirisatian P, Jungteerapanich T, Ritprajak P, Wannigama DL, Tangtanatakul P, Leelahavanichkul A.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms23105445

Bibliografisk träff 2022-02-19

The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia.

Gao ZX, Cui ZL, Zhou MR, Fu Y, Liu F, Zhang L, Ma S, Chen CY.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2022.114948

Bibliografisk träff 2021-10-09

Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15.

Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP.

Cancer Metab · research-article; journal article · DOI 10.1186/s40170-021-00274-5

Bibliografisk träff 2021-06-01

BAM15, a Mitochondrial Uncoupling Agent, Attenuates Inflammation in the LPS Injection Mouse Model: An Adjunctive Anti-Inflammation on Macrophages and Hepatocytes.

Dang CP, Issara-Amphorn J, Charoensappakit A, Udompornpitak K, Bhunyakarnjanarat T, Saisorn W, Sae-Khow K, Leelahavanichkul A.

J Innate Immun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1159/000516348

Bibliografisk träff 2020-09-12

Protonophoric action of BAM15 on planar bilayers, liposomes, mitochondria, bacteria and neurons.

Firsov AM, Popova LB, Khailova LS, Nazarov PA, Kotova EA, Antonenko YN.

Bioelectrochemistry · journal article · DOI 10.1016/j.bioelechem.2020.107673

Bibliografisk träff 2020-06-10

BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control.

Axelrod CL, King WT, Davuluri G, Noland RC, Hall J, Hull M, Dantas WS, Zunica ER, Alexopoulos SJ, Hoehn KL, Langohr I, Stadler K, Doyle H, Schmidt E, Nieuwoudt S, Fitzgerald K, Pergola K, Fujioka H, Mey JT, Fealy C, Mulya A, Beyl R, Hoppel CL, Kirwan JP.

EMBO Mol Med · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.15252/emmm.202012088

Bibliografisk träff 2020-05-14

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.

Alexopoulos SJ, Chen SY, Brandon AE, Salamoun JM, Byrne FL, Garcia CJ, Beretta M, Olzomer EM, Shah DP, Philp AM, Hargett SR, Lawrence RT, Lee B, Sligar J, Carrive P, Tucker SP, Philp A, Lackner C, Turner N, Cooney GJ, Santos WL, Hoehn KL.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-020-16298-2

Bibliografisk träff 2019-02-22

BAM15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.

Tang M, Luo Z, Wu Y, Zhuang J, Li K, Hu D, Rong H, Xian B, Ge J.

Stem Cell Res Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s13287-019-1151-y

Bibliografisk träff 2018-07-26

Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells.

Tai Y, Li L, Peng X, Zhu J, Mao X, Qin N, Ma M, Huo R, Bai Y, Dong D.

Acta Pharm Sin B · research-article; journal article · DOI 10.1016/j.apsb.2018.07.010

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Publications in the selection

Unsymmetric hydroxylamine and hydrazine BAM15 derivatives as potent mitochondrial uncouplers.

Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4-<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Associated Steatohepatitis.

ATP Restoration by ATP-Deprived Cultured Primary Astrocytes.

Correction to "Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease".

Design, synthesis, and biological evaluation of imidazo[4,5-b]pyridine mitochondrial uncouplers for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

Mitochondrial uncoupling caused by a wide variety of protonophores is differently sensitive to carboxyatractyloside in rat heart and liver mitochondria.

Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease.

Characterization of an in vitro model to study CD4<sup>+</sup> T cell metabolism in dairy cows.

Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice.

Effect of the mitochondrial uncoupling agent BAM15 against the Toxoplasma gondii RH strain and Prugniaud strain.

Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster.

Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice.

Polymeric Particle BAM15 Targeting Macrophages Attenuates the Severity of LPS-Induced Sepsis: A Proof of Concept for Specific Immune Cell-Targeted Therapy.

BAM15 as a mitochondrial uncoupler: a promising therapeutic agent for diverse diseases.

Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice.

BAM15 treats mouse sepsis and kidney injury, linking mortality, mitochondrial DNA, tubule damage, and neutrophils.

Endogenous Energy Stores Maintain a High ATP Concentration for Hours in Glucose-Depleted Cultured Primary Rat Astrocytes.

BAM15 Relieves Neurodegeneration in Aged <i>Caenorhabditis elegans</i> and Extends Lifespan.

Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice.

The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia.

Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15.

BAM15, a Mitochondrial Uncoupling Agent, Attenuates Inflammation in the LPS Injection Mouse Model: An Adjunctive Anti-Inflammation on Macrophages and Hepatocytes.

Protonophoric action of BAM15 on planar bilayers, liposomes, mitochondria, bacteria and neurons.

BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control.

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.

BAM15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.

Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells.