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Publikationer som ChEBI hänvisar till för DADLE. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

30 hits

Bibliografisk träff 2025-02-25

Delta opioid peptide [D-ala2, D-leu5]-Enkephalin's ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells.

Deng Z, Chen X, Zhang R, Kong L, Fang Y, Guo J, Shen B, Zhang L.

Stroke Vasc Neurol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1136/svn-2023-003080

Bibliografisk träff 2024-11-29

[Retracted] Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D‑Ala2, D‑Leu5)‑enkephalin through inhibition of the MKK7‑JNK signaling pathway.

Wang Z, Tang B, Tang F, Li Y, Zhang G, Zhong L, Dong C, He S.

Mol Med Rep · retraction of publication; retraction notice · DOI 10.3892/mmr.2024.13403

Bibliografisk träff 2024-09-23

Delta Opioid Peptide [d-Ala2, d-Leu5]-Enkephalin Improves Physical and Cognitive Function and Increases Lifespan in Aged Female Mice.

Huo L, Zhang H, Tang C, Cui G, Xue T, Guo H, Yao F, Zhang W, Feng W.

Mol Neurobiol · journal article · DOI 10.1007/s12035-024-04503-y

Bibliografisk träff 2024-02-19

[D-Ala2, D-Leu5]-enkephalin (DADLE) provides protection against myocardial ischemia reperfusion injury by inhibiting Wnt/β-Catenin pathway.

Liu L, Sun Y, Wang Y, Xin J, Chen W.

BMC Cardiovasc Disord · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s12872-024-03790-6

Bibliografisk träff 2022-12-23

Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury.

Zhang R, Chen M, Deng Z, Kong L, Shen B, Zhang L.

Pharmaceutics · research-article; journal article · DOI 10.3390/pharmaceutics15010046

Bibliografisk träff 2022-05-06

[D-Ala2, D-Leu5] Enkephalin Attenuates Hepatic Ischemia-Reperfusion Injury in Cirrhotic Rats.

Liu J, Wang Y, Pan Q, Chen X, Qu Y, Zhu H, Zheng L, Fan Y.

Front Surg · research-article; journal article · DOI 10.3389/fsurg.2022.839296

Bibliografisk träff 2021-02-12

[D-Ala2, D-Leu5] Enkephalin Inhibits TLR4/NF-κB Signaling Pathway and Protects Rat Brains against Focal Ischemia-Reperfusion Injury.

Fu D, Liu H, Zhu J, Xu H, Yao J.

Mediators Inflamm · research-article; journal article · DOI 10.1155/2021/6661620

Bibliografisk träff 2021-01-01

Delta Opioid Receptor Activation with Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin Contributes to Synaptic Improvement in Rat Hippocampus against Global Ischemia.

Zhang G, Lai Z, Gu L, Xu K, Wang Z, Duan Y, Chen H, Zhang M, Zhang J, Zhao Z, Wang S.

Cell Transplant · research support, non-u.s. gov't; research-article; journal article · DOI 10.1177/09636897211041585

Bibliografisk träff 2020-09-11

Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study.

Funcke S, Werner TR, Hein M, Ulmer BM, Hansen A, Eschenhagen T, Hirt MN.

Biomolecules · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/biom10091309

Bibliografisk träff 2020-06-15

Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia.

Lai Z, Gu L, Yu L, Chen H, Yu Z, Zhang C, Xu X, Zhang M, Zhang M, Ma M, Zhao Z, Zhang J.

Cell Biosci · research-article; journal article · DOI 10.1186/s13578-020-00441-z

Bibliografisk träff 2019-10-07

Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury.

Fu D, Liu H, Liu H, Yao J.

Mol Med Rep · research-article; journal article · DOI 10.3892/mmr.2019.10729

Bibliografisk träff 2019-05-06

[D-Ala2, D-Leu5] Enkephalin Improves Liver Preservation During Normothermic Ex Vivo Perfusion.

Beal EW, Kim JL, Reader BF, Akateh C, Maynard K, Washburn WK, Zweier JL, Whitson BA, Black SM.

J Surg Res · journal article; research support, n.i.h., extramural · DOI 10.1016/j.jss.2019.04.010

Bibliografisk träff 2019-01-22

Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin (DADLE) Exerts a Cytoprotective Effect in Astrocytes Exposed to Oxygen-Glucose Deprivation by Inducing Autophagy.

Wang S, Cao X, Duan Y, Zhang G.

Cell Transplant · research support, non-u.s. gov't; research-article; journal article · DOI 10.1177/0963689719825619

Bibliografisk träff 2016-07-01

Protective effect of delta opioid receptor agonist (D-Ala2, D-Leu5) enkephalin on permanent focal cerebral ischemia in rats.

Fu D, Liu H, Zhu H, Li S, Yao J.

Neuroreport · research support, non-u.s. gov't; journal article · DOI 10.1097/wnr.0000000000000604

Retracted publication 2015-06-24

Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D-Ala2, D-Leu5)-enkephalin through inhibition of the MKK7-JNK signaling pathway.

Wang Z, Tang B, Tang F, Li Y, Zhang G, Zhong L, Dong C, He S.

Mol Med Rep · retracted publication; research support, non-u.s. gov't; research-article; journal article · DOI 10.3892/mmr.2015.3991

Bibliografisk träff 2015-01-12

Dose-dependent neuroprotection of delta-opioid peptide [D-Ala(2), D-Leu(5)] enkephalin on spinal cord ischemia-reperfusion injury by regional perfusion into the abdominal aorta in rabbits.

Liu H, Chen B, Li S, Yao J.

J Vasc Surg · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jvs.2014.11.074

Bibliografisk träff 2014-10-08

Protective effect of delta opioid agonist [D-Ala2, D-Leu5] enkephalin on spinal cord ischemia reperfusion injury by regional perfusion into abdominal aorta in rabbits.

Liu H, Chen B, Zhang Y, Qiu Y, Xia Y, Li S, Yao J.

Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2014.09.048

Bibliografisk träff 2013-04-01

[D-Ala2,D-Leu5]-enkephalin (DADLE) and morphine-induced postconditioning by inhibition of mitochondrial permeability transition pore, in human myocardium.

Fuardo M, Lemoine S, Lo Coco C, Hanouz JL, Massetti M.

Exp Biol Med (Maywood) · journal article · DOI 10.1177/1535370212474602

Bibliografisk träff 2012-09-01

Protective effects of the delta opioid peptide [D-Ala2, D-Leu5]enkephalin in an ex vivo model of ischemia/reperfusion in brain slices.

Zheng YJ, Wang XR, Chen HZ, Wu XJ, Zhao YH, Su DS.

CNS Neurosci Ther · research-article; journal article · DOI 10.1111/j.1755-5949.2012.00360.x

Bibliografisk träff 2012-01-28

Genomic analysis of [d-Ala2, d-Leu5] enkephalin preconditioning in cortical neuron and glial cell injury after oxygen deprivation.

Kim H, Lee SW, Park JS, Min JH, Kim HK.

Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.brainres.2012.01.049

Bibliografisk träff 2011-09-08

Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells.

Ananth S, Thakkar SV, Gnana-Prakasam JP, Martin PM, Ganapathy PS, Smith SB, Ganapathy V.

J Pharm Sci · research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/jps.22733

Bibliografisk träff 2011-05-01

Delayed administration of D-Ala2-D-Leu5-enkephalin, a delta-opioid receptor agonist, improves survival in a rat model of sepsis.

Tang CW, Feng WM, Du HM, Bao Y, Zhu M.

Tohoku J Exp Med · research support, non-u.s. gov't; journal article · DOI 10.1620/tjem.224.69

Bibliografisk träff 2011-02-22

Delta opioid peptide [D-Ala2, D-Leu5] enkephalin (DADLE) triggers postconditioning against transient forebrain ischemia.

Wang S, Duan Y, Su D, Li W, Tan J, Yang D, Wang W, Zhao Z, Wang X.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2011.02.006

Bibliografisk träff 2004-09-01

Delta opioid peptide (D-Ala 2, D-Leu 5) enkephalin: linking hibernation and neuroprotection.

Borlongan CV, Wang Y, Su TP.

Front Biosci · review; journal article · DOI 10.2741/1490

Bibliografisk träff 2002-11-01

In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs.

Yang JZ, Chen W, Borchardt RT.

J Pharmacol Exp Ther · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/jpet.102.037135

Bibliografisk träff 2002-11-01

Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.

Chen W, Yang JZ, Andersen R, Nielsen LH, Borchardt RT.

J Pharmacol Exp Ther · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/jpet.102.037143

Bibliografisk träff 2002-01-01

Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells.

Hayashi T, Tsao LI, Su TP.

Synapse · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1002/syn.10019

Bibliografisk träff 2000-09-01

Blockade of dopamine transporter and tyrosine hydroxylase activity loss by [D-Ala(2), D-Leu(5)]enkephalin in methamphetamine-treated CD-1 mice.

Tsao LI, Hayashi T, Su TP.

Eur J Pharmacol · journal article · DOI 10.1016/s0014-2999(00)00616-6

Bibliografisk träff 2000-05-01

Delta opioid peptide[D- Ala(2),D-Leu(5)]enkephalin promotes cell survival.

Su TP.

J Biomed Sci · research support, u.s. gov't, p.h.s.; review; journal article · DOI 10.1007/bf02255466

Bibliografisk träff 2000-02-01

Buccal permeation of [D-Ala(2), D-Leu(5)]enkephalin from liquid crystalline phases of glyceryl monooleate.

Lee J, Kellaway IW.

Int J Pharm · journal article · DOI 10.1016/s0378-5173(99)00357-9

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Publications in the selection

Delta opioid peptide [D-ala2, D-leu5]-Enkephalin's ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells.

[Retracted] Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D‑Ala2, D‑Leu5)‑enkephalin through inhibition of the MKK7‑JNK signaling pathway.

Delta Opioid Peptide [d-Ala2, d-Leu5]-Enkephalin Improves Physical and Cognitive Function and Increases Lifespan in Aged Female Mice.

[D-Ala2, D-Leu5]-enkephalin (DADLE) provides protection against myocardial ischemia reperfusion injury by inhibiting Wnt/β-Catenin pathway.

Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury.

[D-Ala<sup>2</sup>, D-Leu<sup>5</sup>] Enkephalin Attenuates Hepatic Ischemia-Reperfusion Injury in Cirrhotic Rats.

[D-Ala<sup>2</sup>, D-Leu<sup>5</sup>] Enkephalin Inhibits TLR4/NF-<i>κ</i>B Signaling Pathway and Protects Rat Brains against Focal Ischemia-Reperfusion Injury.

Delta Opioid Receptor Activation with Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin Contributes to Synaptic Improvement in Rat Hippocampus against Global Ischemia.

Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study.

Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia.

Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury.

[D-Ala<sup>2</sup>, D-Leu<sup>5</sup>] Enkephalin Improves Liver Preservation During Normothermic Ex Vivo Perfusion.

Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin (DADLE) Exerts a Cytoprotective Effect in Astrocytes Exposed to Oxygen-Glucose Deprivation by Inducing Autophagy.

Protective effect of delta opioid receptor agonist (D-Ala2, D-Leu5) enkephalin on permanent focal cerebral ischemia in rats.

Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D-Ala2, D-Leu5)-enkephalin through inhibition of the MKK7-JNK signaling pathway.

Dose-dependent neuroprotection of delta-opioid peptide [D-Ala(2), D-Leu(5)] enkephalin on spinal cord ischemia-reperfusion injury by regional perfusion into the abdominal aorta in rabbits.

Protective effect of delta opioid agonist [D-Ala2, D-Leu5] enkephalin on spinal cord ischemia reperfusion injury by regional perfusion into abdominal aorta in rabbits.

[D-Ala2,D-Leu5]-enkephalin (DADLE) and morphine-induced postconditioning by inhibition of mitochondrial permeability transition pore, in human myocardium.

Protective effects of the delta opioid peptide [D-Ala2, D-Leu5]enkephalin in an ex vivo model of ischemia/reperfusion in brain slices.

Genomic analysis of [d-Ala2, d-Leu5] enkephalin preconditioning in cortical neuron and glial cell injury after oxygen deprivation.

Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells.

Delayed administration of D-Ala2-D-Leu5-enkephalin, a delta-opioid receptor agonist, improves survival in a rat model of sepsis.

Delta opioid peptide [D-Ala2, D-Leu5] enkephalin (DADLE) triggers postconditioning against transient forebrain ischemia.

Delta opioid peptide (D-Ala 2, D-Leu 5) enkephalin: linking hibernation and neuroprotection.

In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs.

Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.

Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells.

Blockade of dopamine transporter and tyrosine hydroxylase activity loss by [D-Ala(2), D-Leu(5)]enkephalin in methamphetamine-treated CD-1 mice.

Delta opioid peptide[D- Ala(2),D-Leu(5)]enkephalin promotes cell survival.

Buccal permeation of [D-Ala(2), D-Leu(5)]enkephalin from liquid crystalline phases of glyceryl monooleate.