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Publikationer som ChEBI hänvisar till för GSK-923295. Visa hela publikationsregistret

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Publications in the selection

24 hits

Bibliografisk träff 2025-01-12

Identifying potential prognosis markers in relapsed multiple myeloma via integrated bioinformatics analysis and biological experiments.

Xu Y, Cao X, Zhou H, Xu H, Chen B, Bai H.

Curr Res Transl Med · journal article · DOI 10.1016/j.retram.2025.103495

Bibliografisk träff 2024-12-30

CENP-E haploinsufficiency causes chromosome misalignment and spindle assembly checkpoint activation in the spermatogonia.

Chen J, He JJ, Wu S, Deng ZY, Liu YP, Chen JF, Xu Y, Fang HK, Wei YL, She ZY.

Andrology · research support, non-u.s. gov't; journal article · DOI 10.1111/andr.13834

Bibliografisk träff 2024-12-17

Identification of antimitotic sulfonamides inhibiting chromosome congression.

Sawada JI, Matsuno K, Ogo N, Asai A.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2024.116718

Bibliografisk träff 2024-09-01

PCGF2 Acts as an Oncogenic Driver in Colon Cancer through the Upregulation of CENPE.

Luo Q, Chen X, Tang J, Yan W, Li Z.

Discov Med · journal article · DOI 10.24976/discov.med.202436188.166

Bibliografisk träff 2023-12-29

Maximizing Anticancer Response with MPS1 and CENPE Inhibition Alongside Apoptosis Induction.

Pinto B, Silva JPN, Silva PMA, Barbosa DJ, Sarmento B, Tavares JC, Bousbaa H.

Pharmaceutics · research-article; journal article · DOI 10.3390/pharmaceutics16010056

Bibliografisk träff 2023-09-20

CTCF is essential for proper mitotic spindle structure and anaphase segregation.

Chiu K, Berrada Y, Eskndir N, Song D, Fong C, Naughton S, Chen T, Moy S, Gyurmey S, James L, Ezeiruaku C, Capistran C, Lowey D, Diwanji V, Peterson S, Parakh H, Burgess AR, Probert C, Zhu A, Anderson B, Levi N, Gerlitz G, Packard MC, Dorfman KA, Bahiru MS, Stephens AD.

Chromosoma · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1007/s00412-023-00810-w

Bibliografisk träff 2021-12-28

Functional Assessment of Kinesin-7 CENP-E in Spermatocytes using In Vivo Inhibition, Immunofluorescence and Flow Cytometry.

Xu MF, Yang YH, Wei YL, Zhang JL, Lin X, Lin XY, Chen H, She ZY.

J Vis Exp · video-audio media; research support, non-u.s. gov't; journal article · DOI 10.3791/63271

Bibliografisk träff 2021-03-01

CENPE Inhibition Leads to Mitotic Catastrophe and DNA Damage in Medulloblastoma Cells.

Iegiani G, Gai M, Di Cunto F, Pallavicini G.

Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers13051028

Bibliografisk träff 2020-11-25

Kinesin-7 CENP-E regulates the formation and structural maintenance of the acrosome.

She ZY, Yu KW, Wei YL, Zhong N, Lin Y.

Cell Tissue Res · journal article · DOI 10.1007/s00441-020-03341-3

Bibliografisk träff 2020-07-20

P14<sup>ARF</sup>: The Absence that Makes the Difference.

Cilluffo D, Barra V, Di Leonardo A.

Genes (Basel) · brief-report; research support, non-u.s. gov't; journal article · DOI 10.3390/genes11070824

Bibliografisk träff 2020-07-01

Ploidy Leads a Molecular Motor to Walk Different Paths to Drug Resistance.

Real AM, Marsiglia WM, Dar AC.

Cell Chem Biol · comment; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2020.06.019

Bibliografisk träff 2020-05-21

Distinct Mechanisms of Resistance to a CENP-E Inhibitor Emerge in Near-Haploid and Diploid Cancer Cells.

Pisa R, Phua DYZ, Kapoor TM.

Cell Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2020.05.003

Bibliografisk träff 2020-04-20

Kinesin-7 CENP-E regulates chromosome alignment and genome stability of spermatogenic cells.

She ZY, Yu KW, Zhong N, Xiao Y, Wei YL, Lin Y, Li YL, Lu MH.

Cell Death Discov · research-article; journal article · DOI 10.1038/s41420-020-0261-8

Bibliografisk träff 2019-09-14

Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors.

Yamane M, Sawada JI, Ogo N, Ohba M, Ando T, Asai A.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2019.09.028

Bibliografisk träff 2019-02-01

GSK923295 as a potential antihepatocellular carcinoma agent causing delay on liver regeneration after partial hepatectomy.

Tang JC, Wu K, Zheng X, Xu M, Dai Y, Wei SS, Cai XJ.

Chin Med J (Engl) · research-article; journal article · DOI 10.1097/cm9.0000000000000053

Bibliografisk träff 2018-07-05

Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells.

Sima N, Sun W, Gorshkov K, Shen M, Huang W, Zhu W, Xie X, Zheng W, Cheng X.

Transl Oncol · research-article; journal article · DOI 10.1016/j.tranon.2018.06.002

Bibliografisk träff 2016-07-01

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.

Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, Dane MA, Esch A, Feiler HS, Wang NJ, Hardwicke MA, Laquerre S, Jackson J, W Wood K, Weber B, Spellman PT, Aparicio S, Wooster R, Caldas C, Gray JW.

Breast Cancer Res · research-article; journal article · DOI 10.1186/s13058-016-0728-y

Bibliografisk träff 2015-08-01

Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy.

Bennett A, Bechi B, Tighe A, Thompson S, Procter DJ, Taylor SS.

Oncotarget · research support, non-u.s. gov't; research-article; journal article · DOI 10.18632/oncotarget.4879

Bibliografisk träff 2015-02-25

Pgp efflux pump decreases the cytostatic effect of CENP-E inhibitor GSK923295.

Tcherniuk SO, Oleinikov AV.

Cancer Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.canlet.2015.02.040

Bibliografisk träff 2012-09-28

Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.

Mayes PA, Degenhardt YY, Wood A, Toporovskya Y, Diskin SJ, Haglund E, Moy C, Wooster R, Maris JM.

Int J Cancer · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/ijc.27781

Bibliografisk träff 2011-10-22

First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer.

Chung V, Heath EI, Schelman WR, Johnson BM, Kirby LC, Lynch KM, Botbyl JD, Lampkin TA, Holen KD.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; clinical trial, phase i; journal article · DOI 10.1007/s00280-011-1756-z

Bibliografisk träff 2011-05-16

Initial testing of the CENP-E inhibitor GSK923295A by the pediatric preclinical testing program.

Lock RB, Carol H, Morton CL, Keir ST, Reynolds CP, Kang MH, Maris JM, Wozniak AW, Gorlick R, Kolb EA, Houghton PJ, Smith MA.

Pediatr Blood Cancer · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/pbc.23176

Bibliografisk träff 2010-02-18

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.

Wood KW, Lad L, Luo L, Qian X, Knight SD, Nevins N, Brejc K, Sutton D, Gilmartin AG, Chua PR, Desai R, Schauer SP, McNulty DE, Annan RS, Belmont LD, Garcia C, Lee Y, Diamond MA, Faucette LF, Giardiniere M, Zhang S, Sun CM, Vidal JD, Lichtsteiner S, Cornwell WD, Greshock JD, Wooster RF, Finer JT, Copeland RA, Huang PS, Morgans DJ, Dhanak D, Bergnes G, Sakowicz R, Jackson JR.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.0915068107

Bibliografisk träff 2010-01-19

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.

Qian X, McDonald A, Zhou HJ, Adams ND, Parrish CA, Duffy KJ, Fitch DM, Tedesco R, Ashcraft LW, Yao B, Jiang H, Huang JK, Marin MV, Aroyan CE, Wang J, Ahmed S, Burgess JL, Chaudhari AM, Donatelli CA, Darcy MG, Ridgers LH, Newlander KA, Schmidt SJ, Chai D, Colón M, Zimmerman MN, Lad L, Sakowicz R, Schauer S, Belmont L, Baliga R, Pierce DW, Finer JT, Wang Z, Morgan BP, Morgans DJ, Auger KR, Sung CM, Carson JD, Luo L, Hugger ED, Copeland RA, Sutton D, Elliott JD, Jackson JR, Wood KW, Dhanak D, Bergnes G, Knight SD.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml900018m