A Drug Screening Platform for Podocytopathies in Drosophila Nephrocytes.
Spitz D, Wiggering J, Prakash C, Ulbrich MH, Schneider R, Hermle T.
J Am Soc Nephrol · research-article; journal article · DOI 10.1681/asn.0000000677 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för zacopride. Visa hela publikationsregistret
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23 hitsZacopride stimulates 5-HT<sub>4</sub> serotonin receptors in the human atrium.
Neumann J, Hesse C, Hofmann B, Gergs U.
Naunyn Schmiedebergs Arch Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s00210-024-03051-5Activation of Kir2.1 improves myocardial fibrosis by inhibiting Ca <sup>2+</sup> overload and the TGF-β1/Smad signaling pathway.
Rong Y, Zhou X, Guo Z, Zhang Y, Qin W, Li L, Si J, Yang R, Li X, Ma K.
Acta Biochim Biophys Sin (Shanghai) · research-article; journal article · DOI 10.3724/abbs.2023083α<sub>1</sub> -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Chen L, Wang W, Peng X, Liu L, Zhang A, Li X, Ma K, Wang L.
Exp Physiol · research support, non-u.s. gov't; journal article · DOI 10.1113/ep090243The Agonist of Inward Rectifier Potassium Channel (I<sub>K1</sub>) Attenuates Rat Reperfusion Arrhythmias Linked to CaMKII Signaling.
Liu Q, Sun J, Zhang L, Xu Y, Wu B, Cao J.
Int Heart J · journal article · DOI 10.1536/ihj.21-379Zacopride Exerts an Antiarrhythmic Effect by Specifically Stimulating the Cardiac Inward Rectifier Potassium Current in Rabbits: Exploration of a New Antiarrhythmic Strategy.
Lin Y, Li J, Zhu B, Liu Q, Bai X, Chang B, Guo Y, Feng Q, Li X, Wu B, Cao J.
Curr Pharm Des · research support, non-u.s. gov't; journal article · DOI 10.2174/1381612826666200701135508I<sub>K1</sub> channel agonist zacopride suppresses ventricular arrhythmias in conscious rats with healing myocardial infarction.
Zhai X, Qiao X, Zhang L, Wang D, Zhang L, Feng Q, Wu B, Cao J, Liu Q.
Life Sci · journal article · DOI 10.1016/j.lfs.2019.117075I<sub>K1</sub> Channel Agonist Zacopride Alleviates Cardiac Hypertrophy and Failure <i>via</i> Alterations in Calcium Dyshomeostasis and Electrical Remodeling in Rats.
Liu QH, Qiao X, Zhang LJ, Wang J, Zhang L, Zhai XW, Ren XZ, Li Y, Cao XN, Feng QL, Cao JM, Wu BW.
Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2019.00929The IK1/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat.
Zhai XW, Zhang L, Guo YF, Yang Y, Wang DM, Zhang Y, Li P, Niu YF, Feng QL, Wu BW, Cao JM, Liu QH.
PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0177600Effects of zacopride, a moderate I<sub>K1</sub> channel agonist, on triggered arrhythmia and contractility in human ventricular myocardium.
Elnakish MT, Canan BD, Kilic A, Mohler PJ, Janssen PM.
Pharmacol Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.phrs.2016.11.033Pharmacological profile of zacopride and new quaternarized fluorobenzamide analogues on mammalian α7 nicotinic acetylcholine receptor.
Bourdin CM, Lebreton J, Mathé-Allainmat M, Thany SH.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2015.05.094Activation of I(K1) channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction: Retraction.
Författaruppgift saknas
J Cardiovasc Pharmacol · retraction notice · DOI 10.1097/01.fjc.0000462727.05737.2cActivation of IK1 by zacopride: amelioration of left ventricular remodeling, but at what risk?
Curtis MJ.
J Cardiovasc Pharmacol · comment; journal article · DOI 10.1097/fjc.0000000000000140On the risk concerns of zacopride, a moderate IK1 channel agonist with cardiac protective action.
Wu BW, Cao JM.
J Cardiovasc Pharmacol · letter · DOI 10.1097/fjc.0000000000000148Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction.
Liu CF, Liu QH, Liu EL, Zhai XW, Zhang L, Luo TE, Zhang WF, Feng QL, Cui XL, Zhao ZQ, Cao JM, Wu BW.
J Cardiovasc Pharmacol · retracted publication; research support, non-u.s. gov't; journal article · DOI 10.1097/fjc.0000000000000127Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes.
Zhang L, Liu Q, Liu C, Zhai X, Feng Q, Xu R, Cui X, Zhao Z, Cao J, Wu B.
Sci China Life Sci · research support, non-u.s. gov't; journal article · DOI 10.1007/s11427-013-4531-zThe protective effect of St. Thomas cardioplegia enriched with zacopride on the isolated rat heart.
Wu B, Long C, Hei F, Wang S.
Artif Organs · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1525-1594.2012.01547.xA novel discovery of IK1 channel agonist: zacopride selectively enhances IK1 current and suppresses triggered arrhythmias in the rat.
Liu QH, Li XL, Xu YW, Lin YY, Cao JM, Wu BW.
J Cardiovasc Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/fjc.0b013e3182350bccInhibitory effect of zacopride on Cisplatin-induced delayed emesis in ferrets.
Yamakuni H, Nakayama H, Matsui S, Imazumi K, Matsuo M, Mutoh S.
J Pharmacol Sci · comparative study; journal article · DOI 10.1254/jphs.scj05007xZacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats.
Meyer LC, Fuller A, Mitchell D.
Am J Physiol Regul Integr Comp Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajpregu.00440.2005Distribution of S(-)-zacopride-insensitive [125I]R(+)-zacopride binding sites in the rat brain and peripheral tissues.
Ge J, Barnes JM, Towers P, Barnes NM.
Eur J Pharmacol · journal article · DOI 10.1016/s0014-2999(97)01091-1The enantiomers of zacopride: an intra-species comparison of their potencies in functional and anxiolytic models.
Bill DJ, Coleman J, Hallett I, Middlefell VC, Rhodes KF, Fletcher A.
Br J Pharmacol · comparative study; research-article; journal article · DOI 10.1111/j.1476-5381.1995.tb15000.xThe emetic activity of centrally administered cisplatin in cats and its antagonism by zacopride.
Smith WL, Callaham EM, Alphin RS.
J Pharm Pharmacol · journal article · DOI 10.1111/j.2042-7158.1988.tb05202.x