R-zacopride, a 5-HT3 antagonist/5-HT4 agonist, reduces sleep apneas in rats.
Carley DW, Depoortere H, Radulovacki M.
Pharmacol Biochem Behav · journal article · DOI 10.1016/s0091-3057(01)00535-4 PUBLICATION REGISTRY
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10 hitsDistribution of S(-)-zacopride-insensitive [125I]R(+)-zacopride binding sites in the rat brain and peripheral tissues.
Ge J, Barnes JM, Towers P, Barnes NM.
Eur J Pharmacol · journal article · DOI 10.1016/s0014-2999(97)01091-1Stereoselective effects of (R)- and (S)-zacopride on cognitive performance in a spatial navigation task in rats.
Fontana DJ, Daniels SE, Eglen RM, Wong EH.
Neuropharmacology · comparative study; journal article · DOI 10.1016/0028-3908(96)00191-8The enantiomers of zacopride: an intra-species comparison of their potencies in functional and anxiolytic models.
Bill DJ, Coleman J, Hallett I, Middlefell VC, Rhodes KF, Fletcher A.
Br J Pharmacol · comparative study; research-article; journal article · DOI 10.1111/j.1476-5381.1995.tb15000.xCharacterisation of the non-5-HT3 high-affinity 'R' binding site for (R)-zacopride in brain and other tissues.
Kidd FJ, Levy JC, Nielsen M, Hamon M, Gozlan H.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/0922-4106(93)90136-wDifferential modulation of extracellular levels of 5-hydroxytryptamine in the rat frontal cortex by (R)- and (S)-zacopride.
Barnes NM, Cheng CH, Costall B, Ge J, Naylor RJ.
Br J Pharmacol · research-article; journal article · DOI 10.1111/j.1476-5381.1992.tb14492.xThe potent 5-HT3 receptor antagonist (R)-zacopride labels an additional high affinity site in the central nervous system.
Kidd E, Bouchelet de Vendegies I, Levy JC, Hamon M, Gozlan H.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/0014-2999(92)90276-aAnxiolytic-like activity of R(+)- and S(-)-zacopride in mice.
Young R, Johnson DN.
Eur J Pharmacol · comparative study; journal article · DOI 10.1016/0014-2999(91)90338-q5-HT3 receptor agonism may be responsible for the emetic effects of zacopride in the ferret.
Middlefell VC, Price TL.
Br J Pharmacol · research-article; journal article · DOI 10.1111/j.1476-5381.1991.tb12292.xThe differential activities of R (+)- and S(-)-zacopride as 5-HT3 receptor antagonists.
Barnes JM, Barnes NM, Costall B, Domeney AM, Johnson DN, Kelly ME, Munson HR, Naylor RJ, Young R.
Pharmacol Biochem Behav · comparative study; journal article · DOI 10.1016/0091-3057(90)90554-u