Beyond fludarabine: pentostatin plus cyclophosphamide are a well-tolerated alternative in reduced intensity conditioning.
Dimitrova D, Kanakry JA.
Bone Marrow Transplant · letter · DOI 10.1038/s41409-022-01819-y PUBLICATION REGISTRY
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29 hitsTemperature-dependent hydrogen deuterium exchange shows impact of analog binding on adenosine deaminase flexibility but not embedded thermal networks.
Gao S, Zhang W, Barrow SL, Iavarone AT, Klinman JP.
J Biol Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jbc.2022.102350Understanding the mode of inhibition and molecular interaction of taxifolin with human adenosine deaminase.
Rawat RS, Kumar S.
J Biomol Struct Dyn · research support, non-u.s. gov't; journal article · DOI 10.1080/07391102.2021.2006087[Advances in the biosynthesis of pentostatin].
Song Z, Liu H, Duan X, Yang H, Wang C, Lu X, Tian Y.
Sheng Wu Gong Cheng Xue Bao · review; journal article · DOI 10.13345/j.cjb.210066Epitranscriptomics modifier pentostatin indirectly triggers Toll-like receptor 3 and can enhance immune infiltration in tumors.
Tusup M, Kündig TM, Pascolo S.
Mol Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.ymthe.2021.09.022[Simultaneous determination of pentostatin and 2'-amino-2'-deoxyadenosine in fermentation broth by high performance liquid chromatography-tandem mass spectrometry].
Zhao M, Zhang H, Lou T, Zhao K, Wang S.
Se Pu · research-article; journal article · DOI 10.3724/sp.j.1123.2020.09018Pentostatin antagonizes the antiviral activity of MBX-2168 by inhibiting the biosynthesis of the active compound.
Hagen NR, Nguyen ML, Williams JD, Bowlin TL, Gentry BG.
Antiviral Res · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.antiviral.2021.105018Complete remission of aggressive T-cell LGL leukemia with pentostatin therapy: first case report.
Krackeler ML, Broome C, Lai C.
Stem Cell Investig · journal article; case reports; case-report · DOI 10.21037/sci-2020-035Pentostatin
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Journal missing · reviewA <i>BRAF</i>-Negative Classic Hairy Cell Leukemia Patient with Long-Lasting Complete Remission after Rituximab and Pentostatin
Gozzetti A, Sammartano V, Bacchiarri F, Raspadori D, Bocchia M.
Turk J Haematol · letter · DOI 10.4274/tjh.galenos.2020.2020.0204First report of clinical response to venetoclax combination with pentostatin in T-cell-prolymphocytic leukemia (T-PLL).
Alfayez M, Thakral B, Jain P, Ravandi F, Ferrajoli A, Jain N, Pemmaraju N, Wierda W, Kadia T.
Leuk Lymphoma · letter; research support, non-u.s. gov't; research-article; research support, n.i.h., extramural · DOI 10.1080/10428194.2019.1660967Pentostatin, Cyclophosphamide, and Rituximab Followed by Alemtuzumab for Relapsed or Refractory Chronic Lymphocytic Leukemia: A Phase 2 Trial of the ECOG-Acrin Cancer Research Group (E2903).
Kempin S, Sun Z, Kay NE, Paietta EM, Mazza JJ, Ketterling RP, Frankfurt O, Claxton DF, Saltzman JN, Srkalovic G, Callander NS, Gross G, Tallman MS.
Acta Haematol · clinical trial, phase ii; research-article; multicenter study; journal article; research support, n.i.h., extramural · DOI 10.1159/000500164Coupled biosynthesis of cordycepin and pentostatin in <i>Cordyceps militaris</i>: implications for fungal biology and medicinal natural products.
Wellham PAD, Kim DH, Brock M, de Moor CH.
Ann Transl Med · comment; editorial · DOI 10.21037/atm.2019.04.25Long-term overall- and progression-free survival after pentostatin, cyclophosphamide and rituximab therapy for indolent non-Hodgkin lymphoma.
Khashab T, Hagemeister F, Romaguera JE, Fanale MA, Pro B, McLaughlin P, Rodriguez MA, Neelapu SS, Fayad L, Younes A, Feng L, Vega F, Kwak LW, Samaniego F.
Br J Haematol · clinical trial, phase ii; research support, non-u.s. gov't; randomized controlled trial; journal article; research support, n.i.h., extramural · DOI 10.1111/bjh.15814Cordycepin (3'-deoxyadenosine) and pentostatin (deoxycoformycin) against Trypanosoma cruzi.
do Carmo GM, de Sá MF, Grando TH, Gressler LT, Baldissera MD, Monteiro SG, Henker LC, Mendes RE, Stefani LM, Da Silva AS.
Exp Parasitol · journal article · DOI 10.1016/j.exppara.2019.02.016Cordycepin and pentostatin biosynthesis gene identified through transcriptome and proteomics analysis of Cordyceps kyushuensis Kob.
Zhao X, Zhang G, Li C, Ling J.
Microbiol Res · journal article · DOI 10.1016/j.micres.2018.09.005Cumulative experience and long term follow-up of pentostatin-based chemoimmunotherapy trials for patients with chronic lymphocytic leukemia.
Kay NE, LaPlant BR, Pettinger AM, Call TG, Leis JF, Ding W, Parikh SA, Conte MJ, Bowen DA, Shanafelt TD.
Expert Rev Hematol · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; journal article · DOI 10.1080/17474086.2018.1442716Pentostatin therapy for steroid-refractory acute graft versus host disease: identifying those who may benefit.
Ragon BK, Mehta RS, Gulbis AM, Saliba RM, Chen J, Rondon G, Popat UR, Nieto Y, Oran B, Olson AL, Patel K, Hosing CM, Qazilbash MH, Shah N, Kebriaei P, Shpall EJ, Champlin RE, Alousi AM.
Bone Marrow Transplant · research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41409-017-0034-zDurable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia: A Case Report.
Alsuliman T, Lassoued K, Belghoul M, Debbache K, Choufi B.
Dermatol Ther (Heidelb) · journal article; case-report · DOI 10.1007/s13555-017-0216-zFungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin.
Xia Y, Luo F, Shang Y, Chen P, Lu Y, Wang C.
Cell Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.chembiol.2017.09.001Treatment with 3'-deoxyadenosine and deoxycoformycin in mice infected by Trypanosoma cruzi and its side effect on purinergic enzymes.
do Carmo GM, Doleski PH, de Sá MF, Grando TH, Azevedo MI, Manzoni AG, Leal DBR, Gressler LT, Henker LC, Mendes RE, Baldissera MD, Monteiro SG, Stefani LM, Da Silva AS.
Microb Pathog · journal article · DOI 10.1016/j.micpath.2017.10.030Reversal of Low Donor Chimerism after Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion: A Prospective Phase II Multicenter Trial.
Bar M, Flowers MED, Storer BE, Chauncey TR, Pulsipher MA, Thakar MS, Bethge W, Storb R, Maloney DG, Sandmaier BM.
Biol Blood Marrow Transplant · clinical trial, phase ii; research-article; multicenter study; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbmt.2017.10.016Pentostatin, Cyclophosphamide and Rituximab (PCR) Regimen.
Solimando DA, Waddell JA.
Hosp Pharm · research-article; journal article · DOI 10.1310/hpj5111-888Cordycepin (3'-deoxyadenosine) pentostatin (deoxycoformycin) combination treatment of mice experimentally infected with Trypanosoma evansi.
Dalla Rosa L, da Silva AS, Gressler LT, Oliveira CB, Dambrós MG, Miletti LC, França RT, Lopes ST, Samara YN, da Veiga ML, Monteiro SG.
Parasitology · journal article · DOI 10.1017/s0031182012001990Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
Larson ET, Deng W, Krumm BE, Napuli A, Mueller N, Van Voorhis WC, Buckner FS, Fan E, Lauricella A, DeTitta G, Luft J, Zucker F, Hol WG, Verlinde CL, Merritt EA.
J Mol Biol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jmb.2008.06.048Refractory Hodgkin lymphoma responds to pentostatin (2'-deoxycoformycin).
Braiteh F, Ng C, Kurzrock R.
Leuk Lymphoma · letter; case reports · DOI 10.1080/10428190500282019Pentostatin (Nipent) in the treatment of chronic lymphocyte leukemia and hairy cell leukemia.
Dillman RO.
Expert Rev Anticancer Ther · review; journal article · DOI 10.1586/14737140.4.1.27Pentostatin (Nipent) in T-cell lymphomas.
Kurzrock R.
Semin Oncol · research support, non-u.s. gov't; journal article; case reportsComplexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
Wang Z, Quiocho FA.
Biochemistry · comparative study; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/bi980324o