A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers.
Millard M, Gallagher JD, Olenyuk BZ, Neamati N.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm4012438 PUBLICATION REGISTRY
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12 hitsNew potential therapeutic approach for the treatment of B-Cell malignancies using chlorambucil/hydroxychloroquine-loaded anti-CD20 nanoparticles.
Mezzaroba N, Zorzet S, Secco E, Biffi S, Tripodo C, Calvaruso M, Mendoza-Maldonado R, Capolla S, Granzotto M, Spretz R, Larsen G, Noriega S, Lucafò M, Mansilla E, Garrovo C, Marín GH, Baj G, Gattei V, Pozzato G, Núñez L, Macor P.
PLoS One · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0074216Primary uveal lymphoma effectively managed with oral chlorambucil: a case report.
Rospond-Kubiak I, Kocięcki J, Stopa M.
J Med Case Rep · journal article; case-report · DOI 10.1186/1752-1947-7-173Metronomic administration of chlorambucil for treatment of dogs with urinary bladder transitional cell carcinoma.
Schrempp DR, Childress MO, Stewart JC, Leach TN, Tan KM, Abbo AH, de Gortari AE, Bonney PL, Knapp DW.
J Am Vet Med Assoc · clinical trial; journal article · DOI 10.2460/javma.242.11.1534Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007-2010).
Dandrieux JR, Noble PJ, Scase TJ, Cripps PJ, German AJ.
J Am Vet Med Assoc · journal article · DOI 10.2460/javma.242.12.1705Chlorambucil plus Rituximab as Front-Line Therapy in Elderly/Unfit Patients Affected by B-Cell Chronic Lymphocytic Leukemia: Results of a Single-Centre Experience.
Laurenti L, Vannata B, Innocenti I, Autore F, Santini F, Piccirillo N, Za T, Bellesi S, Marietti S, Sica S, Efremov DG, Leone G.
Mediterr J Hematol Infect Dis · research-article; journal article · DOI 10.4084/mjhid.2013.031Immune thrombocytopenia in patients with chronic lymphocytic leukemia treated with cladribine-based regiments or chlorambucil--follow-up of PALG-CLL randomized trials.
Blonski JZ, Robak T, Chojnowski K, Gora-Tybor J, Warzocha K, Ceglarek B, Seferynska I, Calbecka M, Kostyra A, Stella-Holowiecka B, Kloczko J, Dmoszynska A, Kowal M, Lewandowski K, Dwilewicz-Trojaczek J, Wiater E, Kuliczkowski K, Potoczek S, Hellmann A, Mital A, Skotnicki A, Nowak W, Sulek K, Zawilska K, Trelinski J.
Eur J Haematol · research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1111/ejh.12112Synthesis and preliminary in vitro biological evaluation of 7α-testosterone-chlorambucil hybrid designed for the treatment of prostate cancer.
Bastien D, Hanna R, Leblanc V, Asselin É, Bérubé G.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.04.027Addition of rituximab to chlorambucil produces superior event-free survival in the treatment of patients with extranodal marginal-zone B-cell lymphoma: 5-year analysis of the IELSG-19 Randomized Study.
Zucca E, Conconi A, Laszlo D, López-Guillermo A, Bouabdallah R, Coiffier B, Sebban C, Jardin F, Vitolo U, Morschhauser F, Pileri SA, Copie-Bergman C, Campo E, Jack A, Floriani I, Johnson P, Martelli M, Cavalli F, Martinelli G, Thieblemont C.
J Clin Oncol · clinical trial, phase iii; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1200/jco.2011.40.6272Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma.
Leblond V, Johnson S, Chevret S, Copplestone A, Rule S, Tournilhac O, Seymour JF, Patmore RD, Wright D, Morel P, Dilhuydy MS, Willoughby S, Dartigeas C, Malphettes M, Royer B, Ewings M, Pratt G, Lejeune J, Nguyen-Khac F, Choquet S, Owen RG.
J Clin Oncol · research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1200/jco.2012.44.7920Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study.
Lévy M, Copie-Bergman C, Amiot A, Dupuis J, Le Baleur Y, Belhadj K, Hémery F, Sobhani I, Delfau-Larue MH, Leroy K, Haioun C, Delchier JC.
Leuk Lymphoma · journal article · DOI 10.3109/10428194.2012.729832Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins.
Efthimiou M, Stephanou G, Demopoulos NA, Nikolaropoulos SS.
J Appl Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1002/jat.1743