Betulinic acid, a natural compound with potent anticancer effects.
Mullauer FB, Kessler JH, Medema JP.
Anticancer Drugs · research support, non-u.s. gov't; review; journal article · DOI 10.1097/cad.0b013e3283357c62 PUBLICATION REGISTRY
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5 hitsBetulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.
Sawada N, Kataoka K, Kondo K, Arimochi H, Fujino H, Takahashi Y, Miyoshi T, Kuwahara T, Monden Y, Ohnishi Y.
Br J Cancer · research-article; journal article · DOI 10.1038/sj.bjc.6601746Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection.
Cichewicz RH, Kouzi SA.
Med Res Rev · research support, u.s. gov't, p.h.s.; review; journal article · DOI 10.1002/med.10053Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis.
Pisha E, Chai H, Lee IS, Chagwedera TE, Farnsworth NR, Cordell GA, Beecher CW, Fong HH, Kinghorn AD, Brown DM.
Nat Med · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1038/nm1095-1046Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
Fujioka T, Kashiwada Y, Kilkuskie RE, Cosentino LM, Ballas LM, Jiang JB, Janzen WP, Chen IS, Lee KH.
J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np50104a008