Single-step production of the simvastatin precursor monacolin J by engineering of an industrial strain of Aspergillus terreus.
Huang X, Liang Y, Yang Y, Lu X.
Metab Eng · journal article · DOI 10.1016/j.ymben.2017.06.005 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för compactin diol lactone. Visa hela publikationsregistret
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10 hitsCompetitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. 1976.
Endo A, Kuroda M, Tanzawa K.
Atheroscler Suppl · historical article; biography; seminal article; journal article · DOI 10.1016/j.atherosclerosissup.2004.08.021Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes.
Sorensen JL, Auclair K, Kennedy J, Hutchinson CR, Vederas JC.
Org Biomol Chem · research support, non-u.s. gov't; journal article · DOI 10.1039/b207721cComparison of the effect of six compactin-related compounds on cholesterol synthesis in five human cell types.
Sviridov DD, Sviridov DD, Endo A, Pavlov MYu, Repin VS, Smirnov VN.
Lipids · comparative study; journal article · DOI 10.1007/bf02544034Biochemical aspect of HMG CoA reductase inhibitors.
Endo A, Hasumi K.
Adv Enzyme Regul · review; journal article · DOI 10.1016/0065-2571(89)90063-0Microbial conversion of compactin (ML-236B) to ML-236A.
Komagata D, Yamashita H, Endo A.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.39.15746 alpha-Hydroxy-iso-ML-236B (6 alpha-hydroxy-iso-compactin) and ML-236A, microbial transformation products of ML-236B.
Serizawa N, Nakagawa K, Tsujita Y, Terahara A, Kuwano H, Tanaka M.
J Antibiot (Tokyo) · comparative study; journal article · DOI 10.7164/antibiotics.36.918Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Endo A, Tsujita Y, Kuroda M, Tanzawa K.
Eur J Biochem · journal article · DOI 10.1111/j.1432-1033.1977.tb11637.xML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium.
Endo A, Kuroda M, Tsujita Y.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.29.1346Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity.
Endo A, Kuroda M, Tanzawa K.
FEBS Lett · journal article · DOI 10.1016/0014-5793(76)80996-9