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Publications in the selection

13 hits

Bibliografisk träff 2024-01-13

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG.

iScience · research-article; journal article · DOI 10.1016/j.isci.2024.108907

Bibliografisk träff 2021-09-21

Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.

Yokoyama T, Kashihara M, Mizuguchi M.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c00823

Bibliografisk träff 2019-05-20

A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.

Ambrose AJ, Zerio CJ, Sivinski J, Schmidlin CJ, Shi T, Ross AB, Widrick KJ, Johnson SM, Zhang DD, Chapman E.

Bioorg Med Chem Lett · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2019.05.041

Bibliografisk träff 2019-02-28

HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.

Stevens M, Abdeen S, Salim N, Ray AM, Washburn A, Chitre S, Sivinski J, Park Y, Hoang QQ, Chapman E, Johnson SM.

Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2019.02.028

Bibliografisk träff 2017-08-09

Discovery of novel inhibitors of multidrug-resistant Acinetobacter baumannii.

Soojhawon I, Pattabiraman N, Tsang A, Roth AL, Kang E, Noble SM.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2017.08.014

Bibliografisk träff 2017-03-15

Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).

Chen EC, Khuri N, Liang X, Stecula A, Chien HC, Yee SW, Huang Y, Sali A, Giacomini KM.

J Med Chem · journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.6b01317

Bibliografisk träff 2012-07-18

Inhibitors of bacterial tubulin target bacterial membranes <i>in vivo.</i>

Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB.

Medchemcomm · research-article; journal article · DOI 10.1039/c2md20127e

Bibliografisk träff 2010-06-21

Oligochlorophens are potent inhibitors of Bacillus anthracis.

Foss MH, Weibel DB.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1128/aac.00067-10

Bibliografisk träff 2010-02-01

Rational design of indoleamine 2,3-dioxygenase inhibitors.

Röhrig UF, Awad L, Grosdidier A, Larrieu P, Stroobant V, Colau D, Cerundolo V, Simpson AJ, Vogel P, Van den Eynde BJ, Zoete V, Michielin O.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm9014718

Bibliografisk träff 2009-01-26

Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.

Yeh JR, Munson KM, Elagib KE, Goldfarb AN, Sweetser DA, Peterson RT.

Nat Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.147

Bibliografisk träff 2008-11-27

Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes.

Oh KB, Lee JH, Lee JW, Yoon KM, Chung SC, Jeon HB, Shin J, Lee HS.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2008.11.089

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 2003-04-01

Novel openers of Ca2+-dependent large-conductance potassium channels: symmetrical pharmacophore and electrophysiological evaluation of bisphenols.

Li Y, Johnson G, Romine JL, Meanwell NA, Martin SW, Dworetzky SI, Boissard CG, Gribkoff VK, Starrett JE.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(03)00156-2