The potassium channel opener NS1619 modulates calcium homeostasis in muscle cells by inhibiting SERCA.
Wrzosek A.
Cell Calcium · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ceca.2014.03.005 PUBLICATION REGISTRY
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10 hitsBkca opener, NS1619 pretreatment protects against shock-induced vascular hyporeactivity through PDZ-Rho GEF-RhoA-Rho kinase pathway in rats.
Hu Y, Yang G, Xiao X, Liu L, Li T.
J Trauma Acute Care Surg · research support, non-u.s. gov't; journal article · DOI 10.1097/ta.0b013e3182aa2d98Inhalation of the BK(Ca)-opener NS1619 attenuates right ventricular pressure and improves oxygenation in the rat monocrotaline model of pulmonary hypertension.
Revermann M, Neofitidou S, Kirschning T, Schloss M, Brandes RP, Hofstetter C.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0086636Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans.
Crisford A, Murray C, O'Connor V, Edwards RJ, Kruger N, Welz C, von Samson-Himmelstjerna G, Harder A, Walker RJ, Holden-Dye L.
Mol Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1124/mol.111.071043Cytoprotective action of the potassium channel opener NS1619 under conditions of disrupted calcium homeostasis.
Chmielewska L, Malińska D.
Pharmacol Rep · research support, non-u.s. gov't; journal article · DOI 10.1016/s1734-1140(11)70413-3The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells.
Han X, Xi L, Wang H, Huang X, Ma X, Han Z, Wu P, Ma X, Lu Y, Wang G, Zhou J, Ma D.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2008.07.161The K+-channel opener NS1619 increases endothelial NO-synthesis involving p42/p44 MAP-kinase.
Kuhlmann CR, Trümper JR, Abdallah Y, Wiebke Lüdders D, Schaefer CA, Most AK, Backenköhler U, Neumann T, Walther S, Piper HM, Tillmanns H, Erdogan A.
Thromb Haemost · journal article · DOI 10.1160/th04-03-0196NS 1619 activates Ca2+-activated K+ currents in rat vas deferens.
Huang Y, Lau CW, Ho IH.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0014-2999(97)00102-7NS 1619 activates BKCa channel activity in rat cortical neurones.
Lee K, Rowe IC, Ashford ML.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/0014-2999(95)00251-fIon channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle.
Edwards G, Niederste-Hollenberg A, Schneider J, Noack T, Noack T, Weston AH.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.1994.tb17171.x