A review of the anticancer potential of the antimalarial herbal cryptolepis sanguinolenta and its major alkaloid cryptolepine.
Ansah C, Mensah KB.
Ghana Med J · research-article; review; journal article PUBLICATION REGISTRY
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12 hitsInhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine.
Olajide OA, Bhatia HS, de Oliveira AC, Wright CW, Fiebich BL.
Evid Based Complement Alternat Med · research-article; journal article · DOI 10.1155/2013/459723Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: possible involvement of NF-κB and p38 MAPK inhibition.
Olajide OA, Bhatia HS, de Oliveira AC, Wright CW, Fiebich BL.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.02.004Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.
Rocha e Silva LF, Montoia A, Amorim RC, Melo MR, Henrique MC, Nunomura SM, Costa MR, Andrade Neto VF, Costa DS, Dantas G, Lavrado J, Moreira R, Paulo A, Pinto AC, Tadei WP, Zacardi RS, Eberlin MN, Pohlit AM.
Phytomedicine · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2012.09.008Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives.
Lavrado J, Mackey Z, Hansell E, McKerrow JH, Paulo A, Moreira R.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2012.07.104Design and in vitro haemolytic evaluation of cryptolepine hydrochloride-loaded gelatine nanoparticles as a novel approach for the treatment of malaria.
Kuntworbe N, Al-Kassas R.
AAPS PharmSciTech · comparative study; research-article; evaluation study; journal article · DOI 10.1208/s12249-012-9775-6Determination of pKa and forced degradation of the indoloquinoline antimalarial compound cryptolepine hydrochloride.
Kuntworbe N, Alany RG, Brimble M, Al-Kassas R.
Pharm Dev Technol · journal article · DOI 10.3109/10837450.2012.668554Metabolism of cryptolepine and 2-fluorocryptolepine by aldehyde oxidase.
Stell JG, Wheelhouse RT, Wright CW.
J Pharm Pharmacol · journal article · DOI 10.1111/j.2042-7158.2011.01408.xEffects of the anti-malarial compound cryptolepine and its analogues in human lymphocytes and sperm in the Comet assay.
Gopalan RC, Emerce E, Wright CW, Karahalil B, Karakaya AE, Anderson D.
Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2011.09.010Probing ¹³C chemical shielding tensors in cryptolepine and two bromo-substituted analogs for antiplasmodial activity.
Behzadi H, Olyai MR, van der Spoel D.
J Mol Model · journal article · DOI 10.1007/s00894-011-1009-4Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy.
Sengupta S, Chowdhury S, Bosedasgupta S, Wright CW, Majumder HK.
Mol Biol Int · research-article; journal article · DOI 10.4061/2011/187850Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis.
Ahmed F, Toume K, Ohtsuki T, Rahman M, Sadhu SK, Ishibashi M.
Phytother Res · research support, non-u.s. gov't; journal article · DOI 10.1002/ptr.3219