Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line <i>in vitro.</i>
Zhou Y, Xu Y, Wang H, Niu J, Hou H, Jiang Y.
Oncol Lett · research-article; journal article · DOI 10.3892/ol.2013.1666 PUBLICATION REGISTRY
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20 hitsValproic acid, but not levetiracetam, selectively decreases HDAC7 and HDAC2 expression in human ovarian cancer cells.
Kwiecińska P, Wróbel A, Taubøll E, Gregoraszczuk EŁ.
Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2013.10.035Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study.
Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB.
J Surg Res · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.jss.2013.09.016Valproic Acid attenuates disease symptoms and increases endogenous myelin repair by recruiting neural stem cells and oligodendrocyte progenitors in experimental autoimmune encephalomyelitis.
Pazhoohan S, Satarian L, Asghari AA, Salimi M, Kiani S, Mani AR, Javan M.
Neurodegener Dis · research support, non-u.s. gov't; journal article · DOI 10.1159/000352021Adverse drug reactions induced by valproic acid.
Nanau RM, Neuman MG.
Clin Biochem · systematic review; journal article · DOI 10.1016/j.clinbiochem.2013.06.012Valproic acid promotes human hair growth in in vitro culture model.
Jo SJ, Choi SJ, Yoon SY, Lee JY, Park WS, Park PJ, Kim KH, Eun HC, Kwon O.
J Dermatol Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jdermsci.2013.05.007Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC.
Munster P, Marchion D, Bicaku E, Lacevic M, Kim J, Centeno B, Daud A, Neuger A, Minton S, Sullivan D.
Clin Cancer Res · clinical trial, phase ii; research support, non-u.s. gov't; clinical trial, phase i; journal article; research support, n.i.h., extramural · DOI 10.1158/1078-0432.ccr-08-1930Carnitine in the treatment of valproic acid-induced toxicity.
Lheureux PE, Hantson P.
Clin Toxicol (Phila) · review; journal article · DOI 10.1080/15563650902752376Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines.
Schwartz C, Palissot V, Aouali N, Wack S, Brons NH, Leners B, Bosseler M, Berchem G.
Int J Oncol · research support, non-u.s. gov't; journal article · DOI 10.3892/ijo.30.3.573Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B.
Chen J, Ghazawi FM, Bakkar W, Li Q.
Mol Cancer · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1476-4598-5-71The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum.
Boeckeler K, Adley K, Xu X, Jenkins A, Jin T, Williams RS.
Eur J Cell Biol · research support, n.i.h., intramural; research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejcb.2006.04.013Neuroteratogens in man: an overview with special emphasis on the teratogenicity of antiepileptic drugs in pregnancy.
Ornoy A.
Reprod Toxicol · review; journal article · DOI 10.1016/j.reprotox.2006.03.014Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex.
Gobbi G, Janiri L.
Psychopharmacology (Berl) · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1007/s00213-006-0317-3Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid.
Camphausen K, Cerna D, Scott T, Sproull M, Burgan WE, Cerra MA, Fine H, Tofilon PJ.
Int J Cancer · journal article · DOI 10.1002/ijc.20774Schizophrenia, epigenetics and ligand-activated nuclear receptors: a framework for chromatin therapeutics.
Sharma RP.
Schizophr Res · review; journal article · DOI 10.1016/j.schres.2004.03.001Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases.
Göttlicher M.
Ann Hematol · review; journal article · DOI 10.1007/s00277-004-0850-2Valproic acid toxicity: overview and management.
Sztajnkrycer MD.
J Toxicol Clin Toxicol · review; journal article · DOI 10.1081/clt-120014645Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives.
Lampen A, Carlberg C, Nau H.
Eur J Pharmacol · comparative study; journal article · DOI 10.1016/s0014-2999(01)01423-6Effect of L-carnitine supplementation on acute valproate intoxication.
Murakami K, Sugimoto T, Woo M, Nishida N, Muro H.
Epilepsia · research support, non-u.s. gov't; journal article; case reports · DOI 10.1111/j.1528-1157.1996.tb00634.xMethionine reduces the valproic acid-induced spina bifida rate in mice without altering valproic acid kinetics.
Ehlers K, Elmazar MM, Nau H.
J Nutr · research support, non-u.s. gov't; journal article · DOI 10.1093/jn/126.1.67