Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations.
Mayhoub AS.
Bioorg Med Chem · review; journal article · DOI 10.1016/j.bmc.2012.03.049 PUBLICATION REGISTRY
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Publications in the selection
14 hitsStructure of human PNP complexed with ligands.
Canduri F, Silva RG, dos Santos DM, Palma MS, Basso LA, Santos DS, de Azevedo WF.
Acta Crystallogr D Biol Crystallogr · research support, non-u.s. gov't; journal article · DOI 10.1107/s0907444905005421Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.
Traverso JM, Donnay I, Lequarre AS.
Mol Reprod Dev · research support, non-u.s. gov't; journal article · DOI 10.1002/mrd.20247Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
Prakash TP, Prhavc M, Eldrup AB, Cook PD, Carroll SS, Olsen DB, Stahlhut MW, Tomassini JE, MacCoss M, Galloway SM, Hilliard C, Bhat B.
J Med Chem · journal article · DOI 10.1021/jm0495172Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
Eldrup AB, Allerson CR, Bennett CF, Bera S, Bhat B, Bhat N, Bosserman MR, Brooks J, Burlein C, Carroll SS, Cook PD, Getty KL, MacCoss M, McMasters DR, Olsen DB, Prakash TP, Prhavc M, Song Q, Tomassini JE, Xia J.
J Med Chem · journal article · DOI 10.1021/jm030424eThe regiospecific one-pot phosphorylation of either the 5'- or 2'-hydroxyl in 3'-deoxycytidines without protection: critical role of the base.
Howes PD, Slater MJ, Wareing K.
Nucleosides Nucleotides Nucleic Acids · journal article · DOI 10.1081/ncn-120022610Chemo-enzymatic synthesis of 3-deoxy-beta-D-ribofuranosyl purines and study of their biological properties.
Barai VN, Zinchenko AI, Eroshevskaya LA, Zhernosek EV, Balzarini J, De Clercq E, Mikhailopulo IA.
Nucleosides Nucleotides Nucleic Acids · research support, non-u.s. gov't; journal article · DOI 10.1081/ncn-120022626Acquisition of transcriptional competence in the 1-cell mouse embryo: requirement for recruitment of maternal mRNAs.
Aoki F, Hara KT, Schultz RM.
Mol Reprod Dev · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1002/mrd.10227Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3'-deoxycytidine.
King RW, Zecher M, Jefferies MW.
Antivir Chem Chemother · comparative study; journal article · DOI 10.1177/0956320202013006043'-Deoxyribonucleotides inhibit eukaryotic DNA primase.
Izuta S, Kohsaka-Ichikawa M, Yamaguchi T, Saneyoshi M.
J Biochem · journal article · DOI 10.1093/oxfordjournals.jbchem.a021345The effects of purine nucleoside analogs on the response of the RIF-1 tumor to melphalan in vivo.
Horsman MR, Brown DM, Hirst DG, Brown JM.
Int J Radiat Oncol Biol Phys · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/0360-3016(86)90039-8The role in cancer therapy of inhibiting recovery from PLD induced by radiation or bleomycin.
Nakatsugawa S, Dewey WC.
Int J Radiat Oncol Biol Phys · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/0360-3016(84)90362-6Effects of inhibitors of radiation-induced potentially lethal damage repair on chemotherapy in murine tumors.
Nakatsugawa S, Sugahara T.
Int J Radiat Oncol Biol Phys · journal article · DOI 10.1016/0360-3016(82)90616-23'-DEOXYNUCLEOSIDES. 3. ('-DEOXYGUANOSINE.
JENKINS SR, HOLLY FW, WALTON E.
J Org Chem · journal article · DOI 10.1021/jo01019a516