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Publikationer som ChEBI hänvisar till för (Z)-PUGNAc. Visa hela publikationsregistret

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Publications in the selection

22 hits

Bibliografisk träff 2024-11-12

Sevoflurane postconditioning mitigates neuronal hypoxic-ischemic injury via regulating reactive astrocytic STAT3 protein modification.

Jia Y, Song Y, Xue H, Li X, Zhang Y, Fan S, Yang X, Ding Z, Qiu Y, Wu Z, Zhao P.

Chem Biol Interact · journal article · DOI 10.1016/j.cbi.2024.111308

Bibliografisk träff 2021-07-06

The Hexosamine Biosynthetic Pathway as a Therapeutic Target after Cartilage Trauma: Modification of Chondrocyte Survival and Metabolism by Glucosamine Derivatives and PUGNAc in an Ex Vivo Model.

Riegger J, Baumert J, Zaucke F, Brenner RE.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms22147247

Bibliografisk träff 2019-04-12

Computational Studies on the Potency and Selectivity of PUGNAc Derivatives Against GH3, GH20, and GH84 β-N-acetyl-D-hexosaminidases.

Dong L, Shen S, Xu Y, Wang L, Feng R, Zhang J, Lu H.

Front Chem · research-article; journal article · DOI 10.3389/fchem.2019.00235

Bibliografisk träff 2017-04-06

PUGNAc treatment provokes globotetraosylceramide accumulation in human umbilical vein endothelial cells.

Okuda T.

Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2017.04.019

Bibliografisk träff 2016-04-12

Dissecting PUGNAc-mediated inhibition of the pro-survival action of insulin.

Teo CF, El-Karim EG, Wells L.

Glycobiology · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/glycob/cww043

Bibliografisk träff 2016-03-01

Modifying the phenyl group of PUGNAc: reactivity tuning to deliver selective inhibitors for N-acetyl-D-glucosaminidases.

Hattie M, Cekic N, Debowski AW, Vocadlo DJ, Stubbs KA.

Org Biomol Chem · research support, non-u.s. gov't; journal article · DOI 10.1039/c6ob00297h

Bibliografisk träff 2015-11-04

PUGNAc induces protein ubiquitination in C2C12 myotube cells.

Park JH, Lee JE, Moon PG, Baek MC.

Cell Biochem Funct · research support, non-u.s. gov't; journal article · DOI 10.1002/cbf.3150

Bibliografisk träff 2013-10-01

Identification of differentially expressed proteins by treatment with PUGNAc in 3T3-L1 adipocytes through analysis of ATP-binding proteome.

Lee JE, Park JH, Moon PG, Baek MC.

Proteomics · research support, non-u.s. gov't; journal article · DOI 10.1002/pmic.201200549

Bibliografisk träff 2012-09-18

Computational analysis of human OGA structure in complex with PUGNAc and NAG-thiazoline derivatives.

de Alencar NA, Sousa PR, Silva JR, Lameira J, Alves CN, Martí S, Moliner V.

J Chem Inf Model · research support, non-u.s. gov't; journal article · DOI 10.1021/ci2006005

Bibliografisk träff 2012-02-15

PUGNAc treatment leads to an unusual accumulation of free oligosaccharides in CHO cells.

Mehdy A, Morelle W, Rosnoblet C, Legrand D, Lefebvre T, Duvet S, Foulquier F.

J Biochem · journal article · DOI 10.1093/jb/mvs012

Bibliografisk träff 2010-06-01

An improved route to PUGNAc and its galacto-configured congener.

Goddard-Borger ED, Stubbs KA.

J Org Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jo100614b

Bibliografisk träff 2010-05-01

Quantum mechanical/molecular mechanical molecular dynamics simulation of wild-type and seven mutants of CpNagJ in complex with PUGNAc.

Lameira J, Alves CN, Moliner V, Martí S, Castillo R, Tuñón I.

J Phys Chem B · research support, non-u.s. gov't; journal article · DOI 10.1021/jp9115673

Bibliografisk träff 2008-08-15

The synthesis and biological evaluation of some carbocyclic analogues of PUGNAc.

Scaffidi A, Stubbs KA, Vocadlo DJ, Stick RV.

Carbohydr Res · research support, non-u.s. gov't; evaluation study; journal article · DOI 10.1016/j.carres.2008.08.012

Bibliografisk träff 2007-04-01

The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels.

Zou L, Yang S, Hu S, Chaudry IH, Marchase RB, Chatham JC.

Shock · journal article; research support, n.i.h., extramural · DOI 10.1097/01.shk.0000245031.31859.29

Bibliografisk träff 2007-01-01

Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.

Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ.

J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/ja065697o

Bibliografisk träff 2006-04-27

Akt1 is dynamically modified with O-GlcNAc following treatments with PUGNAc and insulin-like growth factor-1.

Gandy JC, Rountree AE, Bijur GN.

FEBS Lett · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.febslet.2006.04.051

Bibliografisk träff 2005-10-07

Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry.

Perreira M, Kim EJ, Thomas CJ, Hanover JA.

Bioorg Med Chem · research support, n.i.h., intramural; journal article · DOI 10.1016/j.bmc.2005.09.013

Bibliografisk träff 2005-06-01

O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.

Park SY, Ryu J, Lee W.

Exp Mol Med · research support, non-u.s. gov't; journal article · DOI 10.1038/emm.2005.30

Bibliografisk träff 2005-03-01

Relationship between protein O-linked glycosylation and insulin-stimulated glucose transport in rat skeletal muscle following calorie restriction or exposure to O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate.

Arias EB, Cartee GD.

Acta Physiol Scand · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1111/j.1365-201x.2004.01403.x

Bibliografisk träff 2004-04-01

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle.

Arias EB, Kim J, Cartee GD.

Diabetes · research support, u.s. gov't, p.h.s.; journal article · DOI 10.2337/diabetes.53.4.921

Bibliografisk träff 1998-02-01

Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate.

Haltiwanger RS, Grove K, Philipsberg GA.

J Biol Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.273.6.3611

Bibliografisk träff 1991-05-01

N-acetylglucosaminono-1,5-lactone oxime and the corresponding (phenylcarbamoyl)oxime. Novel and potent inhibitors of beta-N-acetylglucosaminidase.

Horsch M, Hoesch L, Vasella A, Rast DM.

Eur J Biochem · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1432-1033.1991.tb15976.x