Parapyruvate Induces Neurodegeneration in C57BL/6JNarl Mice via Inhibition of the α-Ketoglutarate Dehydrogenase Complex.
Lee I, Song TY, Chen CL, Yang JJ, Yang NC.
ACS Omega · research-article; journal article · DOI 10.1021/acsomega.3c09469 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för 4-hydroxy-4-methyl-2-oxoglutarate(2-). Visa hela publikationsregistret
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Publications in the selection
8 hitsUsing Taguchi Method to Determine the Optimum Conditions for Synthesizing Parapyruvate.
Lee I, Yang NC.
Molecules · research-article; journal article · DOI 10.3390/molecules27061870Parapyruvate, an Impurity in Pyruvate Supplements, Induces Senescence in Human Fibroblastic Hs68 Cells via Inhibition of the α-Ketoglutarate Dehydrogenase Complex.
Chang SC, Lee I, Ting H, Chang YJ, Yang NC.
J Agric Food Chem · journal article · DOI 10.1021/acs.jafc.8b01138Investigation into the Mode of Phosphate Activation in the 4-Hydroxy-4-Methyl-2-Oxoglutarate/4-Carboxy-4-Hydroxy-2-Oxoadipate Aldolase from Pseudomonas putida F1.
Mazurkewich S, Seah SY.
PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0164556Biochemical and structural analysis of RraA proteins to decipher their relationships with 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolases.
Mazurkewich S, Wang W, Seah SY.
Biochemistry · research support, non-u.s. gov't; journal article · DOI 10.1021/bi401486gStructural and kinetic characterization of 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolase, a protocatechuate degradation enzyme evolutionarily convergent with the HpaI and DmpG pyruvate aldolases.
Wang W, Mazurkewich S, Kimber MS, Seah SY.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m110.159509Cloning, sequencing, and expression of the gene encoding 4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas ochraceae NGJ1.
Maruyama K, Miwa M, Tsujii N, Nagai T, Tomita N, Harada T, Sobajima H, Sugisaki H.
Biosci Biotechnol Biochem · journal article · DOI 10.1271/bbb.65.2701Purification and properties of 4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas ochraceae grown on phthalate.
Maruyama K.
J Biochem · journal article · DOI 10.1093/oxfordjournals.jbchem.a123201