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Publikationer som ChEBI hänvisar till för 4'-hydroxydiclofenac. Visa hela publikationsregistret

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Publications in the selection

13 hits

Bibliografisk träff 2008-06-12

Relationship between CYP2C8 genotypes and diclofenac 5-hydroxylation in healthy Spanish volunteers.

Dorado P, Cavaco I, Cáceres MC, Piedade R, Ribeiro V, Llerena A, Llerena A.

Eur J Clin Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00228-008-0508-4

Bibliografisk träff 2006-11-10

Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

Naisbitt DJ, Sanderson LS, Meng X, Stachulski AV, Clarke SE, Park BK.

Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2006.10.014

Bibliografisk träff 2004-09-29

Diclofenac systemic exposure is not increased when topical diclofenac is applied to ultraviolet-induced erythema.

Magnette JL, Kienzler JL, Sallin D, Ménart C, Nollevaux F, Knops A.

Eur J Clin Pharmacol · clinical trial; journal article · DOI 10.1007/s00228-004-0832-2

Bibliografisk träff 2004-08-01

Diclofenac-induced antibodies against red blood cells are heterogeneous and recognize different epitopes.

Sachs UJ, Santoso S, Röder L, Smart E, Bein G, Kroll H.

Transfusion · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1537-2995.2004.04025.x

Bibliografisk träff 2004-05-01

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.

Kenny JR, Maggs JL, Meng X, Sinnott D, Clarke SE, Park BK, Stachulski AV.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm030891w

Bibliografisk träff 2003-12-01

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

Gómez-Lechón MJ, Ponsoda X, O'Connor E, Donato T, Castell JV, Jover R.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2003.08.003

Bibliografisk träff 2003-09-01

Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.

Hinz B, Rau T, Auge D, Werner U, Ramer R, Rietbrock S, Brune K.

Clin Pharmacol Ther · clinical trial; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1016/s0009-9236(03)00167-x

Bibliografisk träff 2000-03-01

Pharmacokinetics of diclofenac sodium in chronic active hepatitis and alcoholic cirrhosis.

Lill JS, O'Sullivan T, Bauer LA, Horn JR, Carithers R, Strandness DE, Lau H, Chan K, Thakker K.

J Clin Pharmacol · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1177/00912700022008919

Bibliografisk träff 2000-03-01

A major metabolite of aceclofenac, 4'-hydroxy aceclofenac, suppresses the production of interstitial pro-collagenase/proMMP-1 and pro-stromelysin-1/proMMP-3 by human rheumatoid synovial cells.

Yamazaki R, Kawai S, Mizushima Y, Matsuzaki T, Hashimoto S, Yokokura T, Ito A.

Inflamm Res · journal article · DOI 10.1007/s000110050571

Bibliografisk träff 1999-02-01

Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.

Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.

Chem Res Toxicol · journal article · DOI 10.1021/tx9802217

Bibliografisk träff 1999-01-01

Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity.

Bort R, Ponsoda X, Jover R, Gómez-Lechón MJ, Castell JV.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1016/s0022-3565(24)37925-x

Bibliografisk träff 1997-06-01

Aceclofenac blocks prostaglandin E2 production following its intracellular conversion into cyclooxygenase inhibitors.

Yamazaki R, Kawai S, Matsuzaki T, Kaneda N, Hashimoto S, Yokokura T, Okamoto R, Koshino T, Mizushima Y.

Eur J Pharmacol · comparative study; journal article · DOI 10.1016/s0014-2999(97)89179-0

Bibliografisk träff 1990-09-01

Synthesis and quantitative structure-activity relationships of diclofenac analogues.

Moser P, Sallmann A, Wiesenberg I.

J Med Chem · journal article · DOI 10.1021/jm00171a008