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Publikationer som ChEBI hänvisar till för 2-methyl-6-(phenylethynyl)pyridine. Visa hela publikationsregistret

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Publications in the selection

13 hits

Bibliografisk träff 2012-01-20

Structure-activity relationships for negative allosteric mGluR5 modulators.

Kaae BH, Harpsøe K, Kvist T, Mathiesen JM, Mølck C, Gloriam D, Jimenez HN, Uberti MA, Nielsen SM, Nielsen B, Bräuner-Osborne H, Sauerberg P, Clausen RP, Madsen U.

ChemMedChem · research support, non-u.s. gov't; journal article · DOI 10.1002/cmdc.201100578

Bibliografisk träff 2012-01-12

The mGlu5 receptor antagonist MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug.

Inta D, Filipovic D, Lima-Ojeda JM, Dormann C, Pfeiffer N, Gasparini F, Gass P.

Neuropharmacology · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuropharm.2011.12.035

Bibliografisk träff 2011-12-07

Counteracting roles of metabotropic glutamate receptor subtypes 1 and 5 in regulation of pain-related spatial and temporal synaptic plasticity in rat entorhinal-hippocampal pathways.

Liu MG, Lu D, Wang Y, Chen XF, Li Z, Xu Y, Jin JH, Wang RR, Chen J.

Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2011.11.046

Bibliografisk träff 2011-12-01

Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain.

Picker MJ, Daugherty D, Henry FE, Miller LL, Dykstra LA.

Behav Pharmacol · comparative study; research-article; journal article; research support, n.i.h., extramural · DOI 10.1097/fbp.0b013e32834d13a2

Bibliografisk träff 2011-11-10

Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear.

Toth I, Dietz M, Peterlik D, Huber SE, Fendt M, Neumann ID, Flor PJ, Slattery DA.

Neuropharmacology · journal article · DOI 10.1016/j.neuropharm.2011.10.021

Bibliografisk träff 2011-10-27

mGluR5 is involved in proliferation of rat neural progenitor cells exposed to hypoxia with activation of mitogen-activated protein kinase signaling pathway.

Zhao L, Jiao Q, Chen X, Yang P, Zhao B, Zheng P, Liu Y.

J Neurosci Res · research support, non-u.s. gov't; journal article · DOI 10.1002/jnr.22751

Bibliografisk träff 2011-09-22

Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity.

Zhu JW, Yuan JF, Yang HM, Wang ST, Zhang CG, Sun LL, Yang H, Zhang H.

Biochimie · research support, non-u.s. gov't; journal article · DOI 10.1016/j.biochi.2011.09.013

Bibliografisk träff 2011-08-31

Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats.

D'Souza MS, Markou A.

Neuropharmacology · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuropharm.2011.08.028

Bibliografisk träff 2011-08-11

Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes.

Vinkers CH, Hendriksen H, van Oorschot R, Cook JM, Rallipalli S, Huang S, Millan MJ, Olivier B, Groenink L.

Psychopharmacology (Berl) · research-article; journal article · DOI 10.1007/s00213-011-2423-0

Bibliografisk träff 2011-06-10

Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome.

Thomas AM, Bui N, Perkins JR, Yuva-Paylor LA, Paylor R.

Psychopharmacology (Berl) · comparative study; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1007/s00213-011-2375-4

Bibliografisk träff 2011-01-19

Chronic, systemic treatment with a metabotropic glutamate receptor 5 antagonist produces anxiolytic-like effects and reverses abnormal firing activity of projection neurons in the basolateral nucleus of the amygdala in rats with bilateral 6-OHDA lesions.

Chen L, Liu J, Ali U, Gui ZH, Hou C, Fan LL, Wang Y, Wang T.

Brain Res Bull · research support, non-u.s. gov't; journal article · DOI 10.1016/j.brainresbull.2011.01.005

Bibliografisk träff 2011-01-01

The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats.

Rutten K, Van Der Kam EL, De Vry J, Bruckmann W, Tzschentke TM.

Addict Biol · journal article · DOI 10.1111/j.1369-1600.2010.00235.x

Bibliografisk träff 2010-11-10

A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons.

Edwards JG, Gibson HE, Jensen T, Nugent F, Walther C, Blickenstaff J, Kauer JA.

Hippocampus · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/hipo.20884