Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats.
Ishihara Y, Ishii S, Sakai Y, Yamamura N, Onishi Y, Shimamoto N.
J Appl Toxicol · journal article · DOI 10.1002/jat.1578 PUBLICATION REGISTRY
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4 hitsPivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress.
Parry JD, Pointon AV, Lutz U, Teichert F, Charlwood JK, Chan PH, Athersuch TJ, Taylor EL, Singh R, Luo J, Phillips KM, Vetillard A, Lyon JJ, Keun HC, Lutz WK, Gant TW.
Chem Res Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1021/tx800472zOrthovanadate and 2,3-dimethoxy-1,4-naphthoquinone augment growth factor-induced cell proliferation and c-fos gene expression in 3T3-L1 cells.
Chen Y, Chan TM.
Arch Biochem Biophys · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1006/abbi.1993.1387Extracellular glutathione and gamma-glutamyl transpeptidase prevent H2O2-induced injury by 2,3-dimethoxy-1,4-naphthoquinone.
Shi M, Gozal E, Choy HA, Forman HJ.
Free Radic Biol Med · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/0891-5849(93)90125-e