Protease-Mediated Maturation of HIV: Inhibitors of Protease and the Maturation Process.
Adamson CS.
Mol Biol Int · research-article; journal article · DOI 10.1155/2012/604261 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för bevirimat. Visa hela publikationsregistret
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10 hitsThe prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.
Nguyen AT, Feasley CL, Jackson KW, Nitz TJ, Salzwedel K, Air GM, Sakalian M.
Retrovirology · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1742-4690-8-101Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV- 1 maturation inhibitor bevirimat.
Adamson CS, Sakalian M, Salzwedel K, Freed EO.
Retrovirology · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1742-4690-7-36Can the further clinical development of bevirimat be justified?
Wainberg MA, Albert J.
AIDS · editorial · DOI 10.1097/qad.0b013e328331c83bImpact of human immunodeficiency virus type 1 resistance to protease inhibitors on evolution of resistance to the maturation inhibitor bevirimat (PA-457).
Adamson CS, Waki K, Ablan SD, Salzwedel K, Freed EO.
J Virol · research support, n.i.h., intramural; research-article; journal article · DOI 10.1128/jvi.02659-08The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain.
Dafonseca S, Coric P, Gay B, Hong SS, Bouaziz S, Boulanger P.
Virol J · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1743-422x-5-162Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection.
Martin DE, Salzwedel K, Allaway GP.
Antivir Chem Chemother · review; journal article · DOI 10.1177/095632020801900301The maturation inhibitor bevirimat (PA-457) can be active in patients carrying HIV type-1 non-B subtypes and recombinants.
Yebra G, Holguín A.
Antivir Ther · research support, non-u.s. gov't; journal article · DOI 10.1177/135965350801300805Determinants of activity of the HIV-1 maturation inhibitor PA-457.
Li F, Zoumplis D, Matallana C, Kilgore NR, Reddick M, Yunus AS, Adamson CS, Salzwedel K, Martin DE, Allaway GP, Freed EO, Wild CT.
Virology · journal article; research support, n.i.h., extramural · DOI 10.1016/j.virol.2006.07.023Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
Fujioka T, Kashiwada Y, Kilkuskie RE, Cosentino LM, Ballas LM, Jiang JB, Janzen WP, Chen IS, Lee KH.
J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np50104a008