Total synthesis of manzamine A and related alkaloids.
Jakubec P, Hawkins A, Felzmann W, Dixon DJ.
J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/ja308826x PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för manzamine A. Visa hela publikationsregistret
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Publications in the selection
8 hitsManzamine A as a novel inhibitor of herpes simplex virus type-1 replication in cultured corneal cells.
Palem JR, Bedadala GR, El Sayed KA, Hsia SC.
Planta Med · research-article; journal article; research support, n.i.h., extramural · DOI 10.1055/s-0030-1250093A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis.
Guzmán EA, Johnson JD, Linley PA, Gunasekera SE, Wright AE.
Invest New Drugs · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1007/s10637-010-9422-6Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
Peng J, Kudrimoti S, Prasanna S, Odde S, Doerksen RJ, Pennaka HK, Choo YM, Rao KV, Tekwani BL, Madgula V, Khan SI, Wang B, Mayer AM, Jacob MR, Tu LC, Gertsch J, Hamann MT.
J Med Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/jm900672tNeuritogenic activity-guided isolation of a free base form manzamine A from a marine sponge, Acanthostrongylophora aff. ingens (Thiele, 1899).
Zhang B, Higuchi R, Miyamoto T, Van Soest RW.
Chem Pharm Bull (Tokyo) · research support, non-u.s. gov't; journal article · DOI 10.1248/cpb.56.866Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease.
Hamann M, Alonso D, Martín-Aparicio E, Fuertes A, Pérez-Puerto MJ, Castro A, Morales S, Navarro ML, Del Monte-Millán M, Medina M, Pennaka H, Balaiah A, Peng J, Cook J, Wahyuono S, Martínez A.
J Nat Prod · journal article · DOI 10.1021/np060092rIn vivo antimalarial activity of the beta-carboline alkaloid manzamine A.
Ang KK, Holmes MJ, Higa T, Hamann MT, Kara UA.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.44.6.1645-1649.20008-Hydroxymanzamine A, a beta-carboline alkaloid from a sponge, Pachypellina sp.
Ichiba T, Corgiat JM, Scheuer PJ, Kelly-Borges M.
J Nat Prod · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/np50103a027