Ginsenoside Rd for acute ischemic stroke: translating from bench to bedside.
Ye R, Zhao G, Liu X.
Expert Rev Neurother · research support, non-u.s. gov't; review; journal article · DOI 10.1586/ern.13.51 PUBLICATION REGISTRY
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26 hitsProduction of ginsenoside Rd from ginsenoside Rc by α-L-arabinofuranosidase from Caldicellulosiruptor saccharolyticus.
Shin KC, Lee GW, Oh DK.
J Microbiol Biotechnol · research support, non-u.s. gov't; journal article · DOI 10.4014/jmb.1211.11012Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells.
Kim BJ.
J Ginseng Res · research-article; journal article · DOI 10.5142/jgr.2013.37.201Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-κB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats.
Hu G, Wu Z, Yang F, Zhao H, Liu X, Deng Y, Shi M, Zhao G.
Neurol Sci · research support, non-u.s. gov't; journal article · DOI 10.1007/s10072-013-1344-6Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver.
Kim DH, Chung JH, Yoon JS, Ha YM, Bae S, Lee EK, Jung KJ, Kim MS, Kim YJ, Kim MK, Chung HY.
J Ginseng Res · research-article; journal article · DOI 10.5142/jgr.2013.37.54Wound-healing effect of ginsenoside Rd from leaves of Panax ginseng via cyclic AMP-dependent protein kinase pathway.
Kim WK, Song SY, Oh WK, Kaewsuwan S, Tran TL, Kim WS, Sung JH.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2013.01.048Ginsenoside Rd attenuates beta-amyloid-induced tau phosphorylation by altering the functional balance of glycogen synthase kinase 3beta and protein phosphatase 2A.
Li L, Liu Z, Liu J, Tai X, Hu X, Liu X, Wu Z, Zhang G, Shi M, Zhao G.
Neurobiol Dis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.nbd.2013.01.002Ginsenoside Rd maintains adult neural stem cell proliferation during lead-impaired neurogenesis.
Wang B, Feng G, Tang C, Wang L, Cheng H, Zhang Y, Ma J, Shi M, Zhao G.
Neurol Sci · research support, non-u.s. gov't; journal article · DOI 10.1007/s10072-012-1215-6Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis.
Yang XL, Guo TK, Wang YH, Gao MT, Qin H, Wu YJ.
Arch Pharm Res · research support, non-u.s. gov't; journal article · DOI 10.1007/s12272-012-0714-6Promotive effect of ginsenoside Rd on proliferation of neural stem cells in vivo and in vitro.
Lin T, Liu Y, Shi M, Liu X, Li L, Liu Y, Zhao G.
J Ethnopharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jep.2012.05.057Inhibitory effect of ginsenoside-Rd on carrageenan-induced inflammation in rats.
Wang L, Zhang Y, Wang Z, Li S, Min G, Wang L, Chen J, Cheng J, Wu Y.
Can J Physiol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1139/y11-127Ginsenoside-Rd potentiates apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through the mitochondrial pathway.
Li SY, Wang XG, Ma MM, Liu Y, Du YH, Lv XF, Zhou JG, Tang YB, Guan YY.
Apoptosis · research support, non-u.s. gov't; journal article · DOI 10.1007/s10495-011-0671-4Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia.
Zhang Y, Zhou L, Zhang X, Bai J, Shi M, Zhao G.
Neurol Sci · research support, non-u.s. gov't; journal article · DOI 10.1007/s10072-011-0916-6Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial.
Liu X, Wang L, Wen A, Yang J, Yan Y, Song Y, Liu X, Ren H, Wu Y, Li Z, Chen W, Xu Y, Li L, Xia J, Zhao G.
Eur J Neurol · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1111/j.1468-1331.2011.03634.xGinsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis.
Yang XL, Guo TK, Wang YH, Huang YH, Liu X, Wang XX, Li W, Zhao X, Wang LP, Yan S, Wu D, Wu YJ.
Int Immunopharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.intimp.2011.12.014Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway.
Kim DY, Park YG, Quan HY, Kim SJ, Jung MS, Chung SH.
Fitoterapia · research support, non-u.s. gov't; journal article · DOI 10.1016/j.fitote.2011.10.017Anti-metastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation.
Yoon JH, Choi YJ, Cha SW, Lee SG.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2011.08.069Protective effects of ginsenoside Rd against okadaic acid-induced neurotoxicity in vivo and in vitro.
Li L, Liu J, Yan X, Qin K, Shi M, Lin T, Zhu Y, Kang T, Zhao G.
J Ethnopharmacol · journal article · DOI 10.1016/j.jep.2011.08.068Pharmacokinetic, tissue distribution and excretion of ginsenoside-Rd in rodents.
Sun D, Wang B, Shi M, Zhang YX, Zhou LF, Liu ZR, Wu ZL, Jiang W, Han JL, Xiong LZ, Zhao G.
Phytomedicine · journal article · DOI 10.1016/j.phymed.2011.08.061Ginsenoside Rd protects neurons against glutamate-induced excitotoxicity by inhibiting ca(2+) influx.
Zhang C, Du F, Shi M, Ye R, Cheng H, Han J, Ma L, Cao R, Rao Z, Zhao G.
Cell Mol Neurobiol · research-article; evaluation study; journal article · DOI 10.1007/s10571-011-9742-xImmunosuppressive effects of ginsenoside-Rd on skin allograft rejection in rats.
Wang L, Zhang Y, Chen J, Li S, Wang Y, Hu L, Wang L, Wu Y.
J Surg Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jss.2011.06.038Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice.
Ye R, Kong X, Yang Q, Zhang Y, Han J, Zhao G.
Neuropharmacology · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuropharm.2011.05.029Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.
Chan HH, Hwang TL, Reddy MV, Li DT, Qian K, Bastow KF, Lee KH, Wu TS.
J Nat Prod · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/np100851sGinsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia.
Ye R, Zhang X, Kong X, Han J, Yang Q, Zhang Y, Chen Y, Li P, Liu J, Shi M, Xiong L, Zhao G.
Neuroscience · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuroscience.2011.01.007Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats.
Ye R, Yang Q, Kong X, Han J, Zhang X, Zhang Y, Li P, Liu J, Shi M, Xiong L, Zhao G.
Neurochem Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuint.2010.12.015Purification method improvement and characterization of a novel ginsenoside-hydrolyzing beta-glucosidase from Paecilomyces Bainier sp. 229.
Yan Q, Zhou W, Li X, Feng M, Zhou P.
Biosci Biotechnol Biochem · research support, non-u.s. gov't; journal article · DOI 10.1271/bbb.70425