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Publikationer som ChEBI hänvisar till för omacetaxine mepesuccinate. Visa hela publikationsregistret

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Publications in the selection

26 hits

Bibliografisk träff 2013-06-01

The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.

Beranova L, Pombinho AR, Spegarova J, Koc M, Klanova M, Molinsky J, Klener P, Bartunek P, Andera L.

Apoptosis · research support, non-u.s. gov't; journal article · DOI 10.1007/s10495-013-0823-9

Bibliografisk träff 2012-10-11

Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor.

Lindqvist LM, Vikström I, Chambers JM, McArthur K, Ann Anderson M, Henley KJ, Happo L, Cluse L, Johnstone RW, Roberts AW, Kile BT, Croker BA, Burns CJ, Rizzacasa MA, Strasser A, Huang DC.

Cell Death Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/cddis.2012.149

Bibliografisk träff 2012-10-04

Pharmacokinetic study of omacetaxine mepesuccinate administered subcutaneously to patients with advanced solid and hematologic tumors.

Nemunaitis J, Mita A, Stephenson J, Mita MM, Sarantopoulos J, Padmanabhan-Iyer S, Nanda N, Gleich L, Benichou AC, Craig A.

Cancer Chemother Pharmacol · clinical trial; research-article; multicenter study; journal article · DOI 10.1007/s00280-012-1963-2

Bibliografisk träff 2012-09-07

Characterization of 15 polymorphic microsatellite loci for Cephalotaxus oliveri (Cephalotaxaceae), a conifer of medicinal importance.

Miao Y, Lang X, Li S, Su J, Wang Y.

Int J Mol Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/ijms130911165

Bibliografisk träff 2012-09-01

[Cytotoxicity of homoharringtonine on leukemic stem-like cells in AML cell line KG-1].

Shen JP, Yang H, Ni WM, Qian WB.

Zhejiang Da Xue Xue Bao Yi Xue Ban · research support, non-u.s. gov't; journal article

Bibliografisk träff 2012-08-23

Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines.

Kulkarni H, Göring HH, Diego V, Cole S, Walder KR, Collier GR, Blangero J, Carless MA.

BMC Med Genomics · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1186/1755-8794-5-37

Bibliografisk träff 2012-08-17

Homoharringtonine is an effective therapy for patients with polycythemia vera or essential thrombocythemia who have failed or were intolerant to hydroxycarbamide or interferon-α therapy.

Li Y, Zhu J, Ding B.

Int J Clin Oncol · journal article · DOI 10.1007/s10147-012-0453-1

Bibliografisk träff 2012-08-15

Phase 2 study of subcutaneous omacetaxine mepesuccinate after TKI failure in patients with chronic-phase CML with T315I mutation.

Cortes J, Lipton JH, Rea D, Digumarti R, Chuah C, Nanda N, Benichou AC, Craig AR, Michallet M, Nicolini FE, Kantarjian H, Omacetaxine 202 Study Group.

Blood · clinical trial, phase ii; research support, non-u.s. gov't; research-article; multicenter study; journal article · DOI 10.1182/blood-2012-03-415307

Bibliografisk träff 2012-06-20

Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects.

Abdelkafi H, Nay B.

Nat Prod Rep · research support, non-u.s. gov't; journal article · DOI 10.1039/c2np20037f

Bibliografisk träff 2012-06-01

[Establishment of human homoharringtonine-resistant SKM-1 cell line and its biological characteristics].

Zhou F, Tan W, Ma Y, Chen BB, Zhu P, Xu XP, Lin GW.

Zhonghua Xue Ye Xue Za Zhi · research support, u.s. gov't, non-p.h.s.; journal article

Bibliografisk träff 2012-05-13

Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34+ cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine.

Wu L, Li X, Xu F, Chang C, He Q, Zhang Z, Zhang Y.

Ann Hematol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00277-012-1486-2

Bibliografisk träff 2012-02-01

[Effects of interferon-α combined with homoharringtonine on K562 cell proliferation and β-catenin expression].

Shi YY, Cao WK, Liu XN, Deng ZK, Guo H, Feng WT, Ye LL, Zhu JB, Li YF.

Zhongguo Shi Yan Xue Ye Xue Za Zhi · research support, u.s. gov't, non-p.h.s.; journal article

Bibliografisk träff 2012-01-13

Omacetaxine mepesuccinate prevents cytokine-dependent resistance to nilotinib in vitro: potential role of the common β-subunit c of cytokine receptors.

Klag T, Härtel N, Erben P, Schwaab J, Schnetzke U, Schenk T, Hochhaus A, La Rosée P.

Leukemia · research support, non-u.s. gov't; journal article · DOI 10.1038/leu.2011.380

Bibliografisk träff 2011-12-06

Effect of homoharringtonine on bone marrow CD34 + CD117 + cells in patients with chronic myelogenous leukemia.

Li YF, Deng Z, Din BH, Zhu JB.

Leuk Lymphoma · clinical trial; journal article · DOI 10.3109/10428194.2011.635859

Bibliografisk träff 2011-11-10

De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome.

Min X, Na Z, Yanan L, Chunrui L.

J Hematol Oncol · research support, non-u.s. gov't; research-article; journal article; case reports · DOI 10.1186/1756-8722-4-45

Bibliografisk träff 2011-10-01

Omacetaxine mepesuccinate for the treatment of leukemia.

Kim TD, Frick M, le Coutre P.

Expert Opin Pharmacother · journal article · DOI 10.1517/14656566.2011.613378

Bibliografisk träff 2011-10-01

[Effect of homoharringtonine combined with AG490 on JAK2-STAT5 associated signal pathway in HEL cells].

Ren YL, Tong HY.

Zhongguo Shi Yan Xue Ye Xue Za Zhi · journal article

Bibliografisk träff 2011-08-04

Efficacy and safety of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as induction chemotherapy for elderly patients with high-risk MDS or AML transformed from MDS.

Wu L, Li X, Su J, He Q, Zhang X, Chang C, Pu Q.

J Cancer Res Clin Oncol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s00432-011-1020-2

Bibliografisk träff 2011-04-21

Homoharringtonine as a backbone drug for the treatment of newly diagnosed pediatric acute myeloid leukemia: a report from a single institution in China.

Tang J, Liu Y, Chen J, Xue H, Pan C, Gu L.

Int J Hematol · research support, non-u.s. gov't; journal article · DOI 10.1007/s12185-011-0837-4

Bibliografisk träff 2011-04-05

Omacetaxine may have a role in chronic myeloid leukaemia eradication through downregulation of Mcl-1 and induction of apoptosis in stem/progenitor cells.

Allan EK, Holyoake TL, Craig AR, Jørgensen HG.

Leukemia · research support, non-u.s. gov't; journal article · DOI 10.1038/leu.2011.55

Bibliografisk träff 2011-03-17

Bcl-xL is a dominant antiapoptotic protein that inhibits homoharringtonine-induced apoptosis in leukemia cells.

Yin S, Wang R, Zhou F, Zhang H, Jing Y.

Mol Pharmacol · journal article · DOI 10.1124/mol.110.068528

Bibliografisk träff 2011-01-22

High-dose homoharringtonine versus standard-dose daunorubicin is effective and safe as induction and post-induction chemotherapy for elderly patients with acute myeloid leukemia: a multicenter experience from China.

Huang BT, Zeng QC, Yu J, Liu XL, Xiao Z, Zhu HQ.

Med Oncol · clinical trial; research support, non-u.s. gov't; multicenter study; journal article · DOI 10.1007/s12032-011-9820-4

Bibliografisk träff 2011-01-01

Omacetaxine as an anticancer therapeutic: what is old is new again.

Wetzler M, Segal D.

Curr Pharm Des · research support, non-u.s. gov't; review; journal article; research support, n.i.h., extramural · DOI 10.2174/138161211795049778

Bibliografisk träff 2011-01-01

[The efficacy and safety of HAA regimen as induction chemotherapy in 150 newly diagnosed acute myeloid leukemia].

Song YP, Tong Y, Qian WB, Mai WY, Meng HT, Qian JJ, Tong HY, Huang J, Mao LP, Xu WL, Jin J.

Zhonghua Nei Ke Za Zhi · research support, non-u.s. gov't; evaluation study; journal article

Bibliografisk träff 2010-12-09

Low dose of homoharringtonine and cytarabine combined with granulocyte colony-stimulating factor priming on the outcome of relapsed or refractory acute myeloid leukemia.

Gu LF, Zhang WG, Wang FX, Cao XM, Chen YX, He AL, Liu J, Ma XR.

J Cancer Res Clin Oncol · research-article; journal article · DOI 10.1007/s00432-010-0947-z

Bibliografisk träff 2010-10-22

Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.

Chen R, Guo L, Chen Y, Jiang Y, Wierda WG, Plunkett W.

Blood · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1182/blood-2010-01-262808