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Publications in the selection

9 hits

Bibliografisk träff 2023-05-29

Design, synthesis and anti-NASH effect evaluation of novel GFT505 derivatives in vitro and in vivo.

Xiang C, Chen X, Yao J, Yang N, Yu J, Qiu Q, Zhang S, Kong X, Zhao L, Fan ZC, Yu P, Teng YO.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115510

Bibliografisk träff 2022-01-21

Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis.

Feng Z, Xiang J, Liu H, Li J, Xu X, Sun G, Zheng R, Zhang S, Liu J, Yang S, Xu Q, Wen X, Yuan H, Sun H, Dai L.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c02002

Bibliografisk träff 2021-08-25

Discovery of the first-in-class dual PPARδ/γ partial agonist for the treatment of metabolic syndrome.

Li Z, Ren Q, Zhou Z, Cai Z, Wang B, Han J, Zhang L.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113807

Bibliografisk träff 2021-07-06

Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening.

Hernandez-Olmos V, Heering J, Bischoff-Kont I, Kaps A, Rajkumar R, Liu T, Fürst R, Steinhilber D, Proschak E.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.1c00240

Bibliografisk träff 2021-04-01

Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities.

Zhang C, Yue H, Sun P, Hua L, Liang S, Ou Y, Wu D, Wu X, Chen H, Hao Y, Hu W, Yang Z.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113417

Bibliografisk träff 2021-03-20

Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.

Liu K, Zhao X, Qi X, Hou DL, Li HB, Gu YH, Xu QL.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113388

Bibliografisk träff 2020-04-18

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.

Yang Y, Zhao Y, Li W, Wu Y, Wang X, Wang Y, Liu T, Ye T, Xie Y, Cheng Z, He J, Bai P, Zhang Y, Ouyang L.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2020.112311

Bibliografisk träff 2020-01-29

The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.

Romero FA, Jones CT, Xu Y, Fenaux M, Halcomb RL.

J Med Chem · review; journal article · DOI 10.1021/acs.jmedchem.9b01701

Bibliografisk träff 2019-06-24

Discovery of a Novel Selective Dual Peroxisome Proliferator-Activated Receptor α/δ Agonist for the Treatment of Primary Biliary Cirrhosis.

Jiang Z, Liu X, Yuan Z, He H, Wang J, Zhang X, Gong Z, Hou L, Shen L, Guo F, Zhang J, Wang J, Xu D, Liu Z, Li H, Chen X, Long C, Li J, Chen S.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.9b00189