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Publications in the selection

13 hits

Bibliografisk träff 2024-08-21

Discovery of Novel Antiosteoporosis Leads with Bone Resorption Inhibition and Anabolic Promotion through a Chemotype-Assembly Approach.

Huang D, Zhao C, Li R, Yao N, Xu J, Gu Q.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.4c00909

Bibliografisk träff 2023-01-20

Efficacy, Mechanism, and Structure-Activity Relationship of 6-Methoxy Benzofuran Derivatives as a Useful Tool for Senile Osteoporosis.

Zhou ZY, Sun LQ, Han XY, Wang YJ, Xie ZS, Xue ST, Li ZR.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.2c01377

Bibliografisk träff 2022-09-26

Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases.

Alhayek A, Abdelsamie AS, Schönauer E, Camberlein V, Hutterer E, Posselt G, Serwanja J, Blöchl C, Huber CG, Haupenthal J, Brandstetter H, Wessler S, Hirsch AKH.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.2c00785

Bibliografisk träff 2021-02-26

<i>Agaricus bisporus</i>-Derived Glucosamine Hydrochloride Facilitates Skeletal Injury Repair through Bmp Signaling in Zebrafish Osteoporosis Model.

Peng W, Zhang W, Wu Q, Cai S, Jia T, Sun J, Lin Z, Alitongbieke G, Chen Y, Su Y, Lin J, Cai L, Sun Y, Pan Y, Xue Y.

J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jnatprod.1c00002

Bibliografisk träff 2021-01-13

Synthesis and evaluation of andrographolide derivatives as potent anti-osteoporosis agents in vitro and in vivo.

Zhang S, Zhang Y, Fang Y, Chen H, Hao M, Tan Q, Hu C, Zhou H, Xu J, Gu Q.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113185

Bibliografisk träff 2020-04-19

Synthesis and biological activities of drugs for the treatment of osteoporosis.

Zhou S, Huang G, Chen G.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2020.112313

Bibliografisk träff 2019-07-01

Benzylideneacetone Derivatives Inhibit Osteoclastogenesis and Activate Osteoblastogenesis Independently Based on Specific Structure-Activity Relationship.

Pativada T, Kim MH, Lee JH, Hong SS, Choi CW, Choi YH, Kim WJ, Song DW, Park SI, Lee EJ, Seo BY, Kim H, Kim HK, Lee KH, Ahn SK, Ku JM, Park GH.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.9b00270

Bibliografisk träff 2015-08-12

Synthesis of new indole-based bisphosphonates and evaluation of their chelating ability in PE/CA-PJ15 cells.

Palmerini CA, Tartacca F, Mazzoni M, Granieri L, Goracci L, Scrascia A, Lepri S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.08.019

Bibliografisk träff 2015-06-08

Novel Pyrazole Derivatives Effectively Inhibit Osteoclastogenesis, a Potential Target for Treating Osteoporosis.

Kuo TH, Lin TH, Yang RS, Kuo SC, Fu WM, Hung HY.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm502014h

Bibliografisk träff 2013-08-16

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.

Toxicol Sci · journal article · DOI 10.1093/toxsci/kft176

Bibliografisk träff 2009-03-26

A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells.

Kasser J, Nazarov AA, Hartinger CG, Wdziekonski B, Dani C, Kuznetsov ML, Arion VB, Keppler BK.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.03.039

Bibliografisk träff 2008-12-31

Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity.

Li JF, Zhao Y, Cai MM, Li XF, Li JX.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2008.12.024

Bibliografisk träff 2003-04-01

Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism.

Reichenberg A, Hintz M, Kletschek Y, Kuhl T, Haug C, Engel R, Moll J, Ostrovsky DN, Jomaa H, Eberl M.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(03)00138-0