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Publikationer som ChEBI hänvisar till för mitozolomide. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

7 hits

Bibliografisk träff 2013-08-16

Synthesis and quantitative structure-activity relationship of imidazotetrazine prodrugs with activity independent of O6-methylguanine-DNA-methyltransferase, DNA mismatch repair, and p53.

Pletsas D, Garelnabi EA, Li L, Phillips RM, Wheelhouse RT.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/jm401121k

Bibliografisk träff 2012-09-18

Strategy for Imidazotetrazine Prodrugs with Anticancer Activity Independent of MGMT and MMR.

Garelnabi EA, Pletsas D, Li L, Kiakos K, Karodia N, Hartley JA, Phillips RM, Wheelhouse RT.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml300132t

Bibliografisk träff 2002-12-01

Antitumor imidazotetrazines. 41. Conjugation of the antitumor agents mitozolomide and temozolomide to peptides and lexitropsins bearing DNA major and minor groove-binding structural motifs.

Arrowsmith J, Jennings SA, Clark AS, Stevens MF.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm020936d

Bibliografisk träff 1995-04-01

Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drug temozolomide.

Clark AS, Deans B, Stevens MF, Tisdale MJ, Wheelhouse RT, Denny BJ, Hartley JA.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00009a010

Bibliografisk träff 1990-05-01

Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agents.

Horspool KR, Stevens MF, Newton CG, Lunt E, Walsh RJ, Pedgrift BL, Baig GU, Lavelle F, Fizames C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00167a018

Bibliografisk träff 1987-02-01

Antitumor imidazotetrazines. 14. Synthesis and antitumor activity of 6- and 8-substituted imidazo[5,1-d]-1,2,3,5-tetrazinones and 8-substituted pyrazolo[5,1-d]-1,2,3,5-tetrazinones.

Lunt E, Newton CG, Smith C, Stevens GP, Stevens MF, Straw CG, Walsh RJ, Warren PJ, Fizames C, Lavelle F.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00385a018

Bibliografisk träff 1984-02-01

Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.

Stevens MF, Hickman JA, Stone R, Gibson NW, Baig GU, Lunt E, Newton CG.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00368a016