Metabolically programmed iron chelators.
Bergeron RJ, Bharti N, McManis JS, Wiegand J.
Bioorg Med Chem · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.bmc.2015.06.059 PUBLICATION REGISTRY
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8 hitsDesign, synthesis, and testing of non-nephrotoxic desazadesferrithiocin polyether analogues.
Bergeron RJ, Wiegand J, McManis JS, Bharti N, Singh S.
J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm800154mThe design, synthesis, and evaluation of organ-specific iron chelators.
Bergeron RJ, Wiegand J, McManis JS, Bharti N.
J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm0608816(S)-4,5-dihydro-2-(2-hydroxy-4-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid polyethers: a solution to nephrotoxicity.
Bergeron RJ, Wiegand J, McManis JS, Vinson JR, Yao H, Bharti N, Rocca JR.
J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm0508944Polyamine-vectored iron chelators: the role of charge.
Bergeron RJ, Bharti N, Wiegand J, McManis JS, Yao H, Prokai L.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1021/jm048974fPartition-variant desferrithiocin analogues: organ targeting and increased iron clearance.
Bergeron RJ, Wiegand J, McManis JS, Weimar WR, Park JH, Eiler-McManis E, Bergeron J, Brittenham GM.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm049306xMethoxylation of desazadesferrithiocin analogues: enhanced iron clearing efficiency.
Bergeron RJ, Wiegand J, McManis JS, Bussenius J, Smith RE, Weimar WR.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm020412dEffects of C-4 stereochemistry and C-4' hydroxylation on the iron clearing efficiency and toxicity of desferrithiocin analogues.
Bergeron RJ, Wiegand J, McManis JS, McCosar BH, Weimar WR, Brittenham GM, Smith RE.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm990058s