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Publications in the selection

17 hits

Bibliografisk träff 2024-04-02

Design, docking optimization, and evaluation of biotin-PEG4-1,8-naphthalimide as a potent and safe antitumor agent with dual targeting of ferroptosis and DNA.

Wang Q, Liang SM, Mao ZC, Ma XL, Wei JH, Huang RZ, Zhang Y.

RSC Med Chem · research-article; journal article · DOI 10.1039/d4md00134f

Bibliografisk träff 2023-11-10

Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance.

Liang SM, Liang GB, Wang HL, Jiang H, Ma XL, Wei JH, Huang RZ, Zhang Y.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115937

Bibliografisk träff 2023-10-11

Novel 1,8-Naphthalimide Derivatives As Antitumor Agents and Potent Demethylase Inhibitors.

Ge C, Liu L, Wang Y, Di X, Luo X, Liu H, Qian Y.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.3c00353

Bibliografisk träff 2023-03-07

Design, synthesis, and antitumor evaluation of morpholine substituted bisnaphthalimides as DNA targeting agents.

Chen XM, Zhou JY, Liu SQ, Song LH, Wang HL, Wang Q, Liang SM, Lu L, Wei JH, Huang R, Zhang Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2023.129218

Bibliografisk träff 2020-10-17

Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.

Liang GB, Wei JH, Jiang H, Huang RZ, Qin JT, Wang HL, Wang HS, Zhang Y.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112951

Bibliografisk träff 2020-02-19

Design, synthesis and biological evaluation of 3-nitro-1,8-naphthalimides as potential antitumor agents.

Xin M, Wei JH, Yang CH, Liang GB, Su D, Ma XL, Zhang Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2020.127051

Bibliografisk träff 2018-09-24

l,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017.

Tomczyk MD, Walczak KZ.

Eur J Med Chem · systematic review; journal article · DOI 10.1016/j.ejmech.2018.09.055

Bibliografisk träff 2017-04-21

Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.

Karelia DN, Sk UH, Singh P, Gowda ASP, Pandey MK, Ramisetti SR, Amin S, Sharma AK.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.04.052

Bibliografisk träff 2015-04-17

Effect of intercalator substituent and nucleotide sequence on the stability of DNA- and RNA-naphthalimide complexes.

Johnson CA, Hudson GA, Hardebeck LK, Jolley EA, Ren Y, Lewis M, Znosko BM.

Bioorg Med Chem · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bmc.2015.04.030

Bibliografisk träff 2009-12-01

Design, synthesis, and biological evaluation of substituted naphthalene imides and diimides as anticancer agent.

Tumiatti V, Milelli A, Minarini A, Micco M, Gasperi Campani A, Roncuzzi L, Baiocchi D, Marinello J, Capranico G, Zini M, Stefanelli C, Melchiorre C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm901131m

Bibliografisk träff 2008-08-15

Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs.

Antonini I, Volpini R, Dal Ben D, Lambertucci C, Cristalli G.

Bioorg Med Chem · evaluation study; journal article · DOI 10.1016/j.bmc.2008.08.027

Bibliografisk träff 2007-07-21

2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.

Van Quaquebeke E, Mahieu T, Dumont P, Dewelle J, Ribaucour F, Simon G, Sauvage S, Gaussin JF, Tuti J, El Yazidi M, Van Vynckt F, Mijatovic T, Lefranc F, Darro F, Kiss R.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm070315q

Bibliografisk träff 2007-02-09

Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation.

Yin H, Xu Y, Qian X, Li Y, Liu J.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.02.015

Bibliografisk träff 2006-11-01

Synthesis and biological evaluation of new asymmetrical bisintercalators as potential antitumor drugs.

Antonini I, Santoni G, Lucciarini R, Amantini C, Sparapani S, Magnano A.

J Med Chem · journal article · DOI 10.1021/jm0606793

Bibliografisk träff 2005-06-01

A new synthetic agent with potent but selective cytotoxic activity against cancer.

Cholody WM, Kosakowska-Cholody T, Hollingshead MG, Hariprakasha HK, Michejda CJ.

J Med Chem · journal article · DOI 10.1021/jm048946x

Bibliografisk träff 1997-02-01

Chromophore-modified bis-naphthalimides: synthesis and antitumor activity of bis-dibenz[de,h]isoquinoline-1,3-diones.

Braña MF, Castellano JM, Perron D, Maher C, Conlon D, Bousquet PF, George J, Qian XD, Robinson SP.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm960295k

Bibliografisk träff 1984-04-01

Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.

Feigon J, Denny WA, Leupin W, Kearns DR.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00370a007