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Publikationer som ChEBI hänvisar till för zidovudine triphosphate. Visa hela publikationsregistret

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Publications in the selection

23 hits

Bibliografisk träff 2016-07-07

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors.

Elgaher WA, Sharma KK, Haupenthal J, Saladini F, Pires M, Real E, Mély Y, Hartmann RW.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.6b00730

Bibliografisk träff 2013-10-28

Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus.

Sirivolu VR, Vernekar SK, Ilina T, Myshakina NS, Parniak MA, Wang Z.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm401232v

Bibliografisk träff 2011-05-30

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.

Zhang HW, Detorio M, Herman BD, Solomon S, Bassit L, Nettles JH, Obikhod A, Tao SJ, Mellors JW, Sluis-Cremer N, Coats SJ, Schinazi RF.

Eur J Med Chem · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ejmech.2011.05.051

Bibliografisk träff 2010-04-03

Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility.

Nieman JA, Nair SK, Heasley SE, Schultz BL, Zerth HM, Nugent RA, Chen K, Stephanski KJ, Hopkins TA, Knechtel ML, Oien NL, Wieber JL, Wathen MW.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2010.03.115

Bibliografisk träff 2010-01-25

The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.

Tanis SP, Strohbach JW, Parker TT, Moon MW, Thaisrivongs S, Perrault WR, Hopkins TA, Knechtel ML, Oien NL, Wieber JL, Stephanski KJ, Wathen MW.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2010.01.094

Bibliografisk träff 2009-07-13

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.

Sluis-Cremer N, Koontz D, Bassit L, Hernandez-Santiago BI, Detorio M, Rapp KL, Amblard F, Bondada L, Grier J, Coats SJ, Schinazi RF, Mellors JW.

Antimicrob Agents Chemother · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00392-09

Bibliografisk träff 2008-06-20

Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.

Schnute ME, Brideau RJ, Collier SA, Cudahy MM, Hopkins TA, Knechtel ML, Oien NL, Sackett RS, Scott A, Stephan ML, Wathen MW, Wieber JL.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.06.060

Bibliografisk träff 2007-10-29

Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.

Zelina S, Sheen CW, Radzio J, Mellors JW, Sluis-Cremer N.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00904-07

Bibliografisk träff 2007-05-21

Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir.

Marchand B, White KL, Ly JK, Margot NA, Wang R, McDermott M, Miller MD, Götte M.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00314-07

Bibliografisk träff 2007-05-10

7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.

Larsen SD, Zhang Z, DiPaolo BA, Manninen PR, Rohrer DC, Hageman MJ, Hopkins TA, Knechtel ML, Oien NL, Rush BD, Schwende FJ, Stefanski KJ, Wieber JL, Wilkinson KF, Zamora KM, Wathen MW, Brideau RJ.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2007.05.010

Bibliografisk träff 2007-04-30

Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.

Shi M, Wang X, De Clercq E, Takao S, Baba M.

Antimicrob Agents Chemother · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00212-07

Bibliografisk träff 2007-04-05

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.

Schnute ME, Anderson DJ, Brideau RJ, Ciske FL, Collier SA, Cudahy MM, Eggen M, Genin MJ, Hopkins TA, Judge TM, Kim EJ, Knechtel ML, Nair SK, Nieman JA, Oien NL, Scott A, Tanis SP, Vaillancourt VA, Wathen MW, Wieber JL.

Bioorg Med Chem Lett · comparative study; journal article · DOI 10.1016/j.bmcl.2007.03.102

Bibliografisk träff 2007-04-02

Biochemical studies on the mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to 1-(beta-D-dioxolane)thymine triphosphate.

Lennerstrand J, Chu CK, Schinazi RF.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00119-07

Bibliografisk träff 2006-12-15

HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.

Grobler JA, Dornadula G, Rice MR, Simcoe AL, Hazuda DJ, Miller MD.

J Biol Chem · journal article · DOI 10.1074/jbc.m608274200

Bibliografisk träff 2005-09-01

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.

Schnute ME, Cudahy MM, Brideau RJ, Homa FL, Hopkins TA, Knechtel ML, Oien NL, Pitts TW, Poorman RA, Wathen MW, Wieber JL.

J Med Chem · journal article · DOI 10.1021/jm050162b

Bibliografisk träff 2005-04-01

Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Boyle NA, Rajwanshi VK, Prhavc M, Wang G, Fagan P, Chen F, Ewing GJ, Brooks JL, Hurd T, Leeds JM, Bruice TW, Cook PD.

J Med Chem · journal article · DOI 10.1021/jm040101y

Bibliografisk träff 2005-02-01

4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase.

Summerer D, Marx A.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2004.12.072

Bibliografisk träff 2004-12-01

Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase.

Wang G, Boyle N, Chen F, Rajappan V, Fagan P, Brooks JL, Hurd T, Leeds JM, Rajwanshi VK, Jin Y, Prhavc M, Bruice TW, Cook PD.

J Med Chem · journal article · DOI 10.1021/jm040116w

Bibliografisk träff 1996-09-01

Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii.

Pengsuparp T, Serit M, Hughes SH, Soejarto DD, Pezzuto JM.

J Nat Prod · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/np960399y

Bibliografisk träff 1996-05-01

Discovery of novel, non-peptide HIV-1 protease inhibitors by pharmacophore searching.

Wang S, Milne GW, Yan X, Posey IJ, Nicklaus MC, Graham L, Rice WG.

J Med Chem · journal article · DOI 10.1021/jm950874+

Bibliografisk träff 1994-10-01

The synthesis of nucleoside 5'-O-(1,1-dithiotriphosphates).

Okruszek A, Olesiak M, Balzarini J.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00048a021

Bibliografisk träff 1989-07-01

Anti-AIDS agents, 1. Isolation and characterization of four new tetragalloylquinic acids as a new class of HIV reverse transcriptase inhibitors from tannic acid.

Nishizawa M, Yamagishi T, Dutschman GE, Parker WB, Bodner AJ, Kilkuskie RE, Cheng YC, Lee KH.

J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np50064a016

Bibliografisk träff 1989-02-01

1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.

Mansuri MM, Starrett JE, Ghazzouli I, Hitchcock MJ, Sterzycki RZ, Brankovan V, Lin TS, August EM, Prusoff WH, Sommadossi JP.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00122a029