Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.
Yang L, Wang Z.
Eur J Med Chem · research-article; review; journal article · DOI 10.1016/j.ejmech.2023.115503 PUBLICATION REGISTRY
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8 hitsNovel Betulinic Acid-Nucleoside Hybrids with Potent Anti-HIV Activity.
Wang Q, Li Y, Zheng L, Huang X, Wang Y, Chen CH, Cheng YY, Morris-Natschke SL, Lee KH.
ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.0c00414Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention.
Sun L, Peng Y, Yu W, Zhang Y, Liang L, Song C, Hou J, Qiao Y, Qiao Y, Wang Q, Chen J, Wu M, Zhang D, Li E, Han Z, Zhao Q, Jin X, Zhang B, Huang Z, Chai J, Wang JH, Chang J.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c00940Design, synthesis, and biological evaluation of new 1,2,3-triazolo-2'-deoxy-2'-fluoro- 4'-azido nucleoside derivatives as potent anti-HBV agents.
Liu Y, Peng Y, Lu J, Wang J, Ma H, Song C, Liu B, Qiao Y, Yu W, Wu J, Chang J.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.11.028Synthesis and biological evaluation of 4-substituted fluoronucleoside analogs for the treatment of hepatitis B virus infection.
Yang Q, Kang J, Zheng L, Wang XJ, Wan N, Wu J, Qiao Y, Niu P, Wang SQ, Peng Y, Wang Q, Yu W, Chang J.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm5012963Design, synthesis, and biological evaluation of new 2'-deoxy-2'-fluoro-4'-triazole cytidine nucleosides as potent antiviral agents.
Wu J, Yu W, Fu L, He W, Wang Y, Chai B, Song C, Chang J.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.02.042Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents.
Wang Q, Hu W, Wang S, Pan Z, Tao L, Guo X, Qian K, Chen CH, Lee KH, Chang J.
Eur J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ejmech.2011.06.020The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
Smith DB, Kalayanov G, Sund C, Winqvist A, Maltseva T, Leveque VJ, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Kaiser AC, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M.
J Med Chem · journal article · DOI 10.1021/jm801595c