PUBLICATION REGISTRY

Go to research.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för baloxavir. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

11 hits

Bibliografisk träff 2024-07-01

Design and synthesis of 7-membered lactam fused hydroxypyridinones as potent metal binding pharmacophores (MBPs) for inhibiting influenza virus PA<sub>N</sub> endonuclease.

Zhang L, Ke D, Li Y, Zhang H, Zhang X, Wang S, Ni S, Peng B, Zeng H, Hou T, Du Y, Pan P, Yu Y, Chen W.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2024.116639

Bibliografisk träff 2024-05-22

Novel Acyl Thiourea-Based Hydrophobic Tagging Degraders Exert Potent Anti-Influenza Activity through Two Distinct Endonuclease Polymerase Acidic-Targeted Degradation Pathways.

Ma X, Wang X, Chen F, Zou W, Ren J, Xin L, He P, Liang J, Xu Z, Dong C, Lan K, Wu S, Zhou HB.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.4c00131

Bibliografisk träff 2024-02-01

Discovery of a Macrocyclic Influenza Cap-Dependent Endonuclease Inhibitor.

Feng J, Guo F, Li P, Zhang J, Jiang K, Zhu Z, Yin S, Lin X, Lin F, Xiao F, Xue X, He H, Chen S.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.3c01715

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2023-06-10

Nine-valent oleanolic acid conjugates as potent inhibitors blocking the entry of influenza A virus.

Shao L, Su Y, Zhang Y, Yang F, Zhang J, Tang T, Yu F.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115562

Bibliografisk träff 2022-12-15

Identification of N- and C-3-Modified Laudanosoline Derivatives as Novel Influenza PA<sub>N</sub> Endonuclease Inhibitors.

Liao Y, Ye Y, Liu M, Liu Z, Wang J, Li B, Huo L, Zhuang Y, Chen L, Chen J, Gao Y, Ning X, Li S, Liu S, Song G.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.2c00857

Bibliografisk träff 2021-12-14

Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction.

Mizuta S, Otaki H, Ishikawa T, Makau JN, Yamaguchi T, Fujimoto T, Takakura N, Sakauchi N, Kitamura S, Nono H, Nishi R, Tanaka Y, Takeda K, Nishida N, Watanabe K.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c01527

Bibliografisk träff 2021-07-02

Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.

Wu YJ, Meanwell NA.

J Med Chem · review; journal article · DOI 10.1021/acs.jmedchem.1c00790

Bibliografisk träff 2020-08-22

Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.

Zima V, Radilová K, Kožíšek M, Albiñana CB, Karlukova E, Brynda J, Fanfrlík J, Flieger M, Hodek J, Weber J, Majer P, Konvalinka J, Machara A.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112754

Bibliografisk träff 2020-08-17

Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses.

Ivashchenko AA, Mitkin OD, Jones JC, Nikitin AV, Koryakova AG, Ryakhovskiy A, Karapetian RN, Kravchenko DV, Aladinskiy V, Leneva IA, Falynskova IN, Glubokova EA, Govorkova EA, Ivachtchenko AV.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c00565

Bibliografisk träff 2019-10-17

SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease.

Credille CV, Morrison CN, Stokes RW, Dick BL, Feng Y, Sun J, Chen Y, Cohen SM.

J Med Chem · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.9b00747