Germacrone improves liver fibrosis by regulating the PI3K/AKT/mTOR signalling pathway.
Ji, Zhao Q, Qin Y, Tong H, Wang Q, Yu M, Mao C, Lu T, Qiu J, Jiang C.
Cell Biol Int · journal article · DOI 10.1002/cbin.11607 PUBLICATION REGISTRY
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Publications in the selection
34 hitsTerpenoids from Curcumae Rhizoma: Their anticancer effects and clinical uses on combination and versus drug therapies.
Chen Y, Zhu Z, Chen J, Zheng Y, Limsila B, Lu M, Gao T, Yang Q, Fu C, Liao W.
Biomed Pharmacother · comparative study; review; journal article · DOI 10.1016/j.biopha.2021.111350Insecticidal and acetylcholine esterase inhibition activity of <i>Rhododendron thymifolium</i> essential oil and its main constituent against two stored product insects.
Liang JY, Yang YY, An Y, Shao YZ, He CY, Zhang J, Jia LY.
J Environ Sci Health B · journal article · DOI 10.1080/03601234.2021.1894888Fast discrimination and quantification analysis of Curcumae Radix from four botanical origins using NIR spectroscopy coupled with chemometrics tools.
Wang L, Wang X, Liu X, Wang Y, Ren X, Dong Y, Song R, Ma J, Fan Q, Wei J, Yu A, Zhang L, She G.
Spectrochim Acta A Mol Biomol Spectrosc · journal article · DOI 10.1016/j.saa.2021.119626Study on Quality Standards and Hepatoprotective Effect of <i>Curcuma phaeocaulis</i> Radix.
Chen Z, Liao Y, Ao M, Peng Y, Yang Z, Hu C, Yu L.
Evid Based Complement Alternat Med · research-article; journal article · DOI 10.1155/2021/6617009Cucurbituril and zwitterionic surfactant-based matrix solid-phase dispersion microextraction to simultaneously determine terpenoids from Radix Curcumae.
Chen Y, Zhen XT, Yu YL, Shi MZ, Cao J, Zheng H, Ye LH.
J Sep Sci · journal article · DOI 10.1002/jssc.202001067Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress.
Zhuang S, Liu B, Guo S, Xue Y, Wu L, Liu S, Zhang C, Ni X.
BMC Complement Med Ther · research-article; journal article · DOI 10.1186/s12906-020-03175-0Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells.
Fang X, Tan T, Gao B, Zhao Y, Liu T, Xia Q.
Front Oncol · research-article; journal article · DOI 10.3389/fonc.2020.537322Inhibitory activities of curzerenone, curdione, furanodienone, curcumol and germacrone on Ca<sup>2+</sup>-activated chloride channels.
Zhu X, Zhang W, Jin L, Zhang G, Yang H, Yu B.
Fitoterapia · journal article · DOI 10.1016/j.fitote.2020.104736Thai <i>Curcuma</i> Species: Antioxidant and Bioactive Compounds.
Burapan S, Kim M, Paisooksantivatana Y, Eser BE, Han J.
Foods · research-article; journal article · DOI 10.3390/foods9091219Co-delivery of miR-29b and germacrone based on cyclic RGD-modified nanoparticles for liver fibrosis therapy.
Ji, Wang Q, Zhao Q, Tong H, Yu M, Wang M, Lu T, Jiang C.
J Nanobiotechnology · research-article; journal article · DOI 10.1186/s12951-020-00645-yThe Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells.
Zárybnický T, Matoušková P, Skálová L, Boušová I.
Nutrients · research-article; journal article · DOI 10.3390/nu12061720Germacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells.
Yu Z, Xu J, Shao M, Zou J.
Cancer Manag Res · research-article; journal article · DOI 10.2147/cmar.s250522Germacrone protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy processes in PC12 cells.
Zhang J, Yuan L, Wang S, Liu J, Bi H, Chen G, Li J, Chen L.
BMC Complement Med Ther · research-article; journal article · DOI 10.1186/s12906-020-2865-1Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.
Zhang R, Hao J, Guo K, Liu W, Yao F, Wu Q, Liu C, Wang Q, Yang X.
Biomed Res Int · research-article; journal article · DOI 10.1155/2020/7643248Anti-H1N1 viral activity of three main active ingredients from zedoary oil.
Li L, Xie Q, Bian G, Zhang B, Wang M, Wang Y, Chen Z, Li Y.
Fitoterapia · journal article · DOI 10.1016/j.fitote.2020.104489Germacrone exerts anti-cancer effects on gastric cancer through induction of cell cycle arrest and promotion of apoptosis.
Wu L, Wang L, Tian X, Zhang J, Feng H.
BMC Complement Med Ther · research-article; journal article · DOI 10.1186/s12906-019-2810-3Germacrone: A Potent Secondary Metabolite with Therapeutic Potential in Metabolic Diseases, Cancer and Viral Infections.
Riaz A, Rasul A, Kanwal N, Hussain G, Shah MA, Sarfraz I, Ishfaq R, Batool R, Rukhsar F, Adem Ş.
Curr Drug Metab · review; journal article · DOI 10.2174/1389200221999200728144801Germacrone Reduces Cisplatin-Induced Toxicity of Renal Proximal Tubular Cells via Inhibition of Organic Cation Transporter.
Soodvilai S, Meetam P, Siangjong L, Chokchaisiri R, Suksamrarn A, Soodvilai S.
Biol Pharm Bull · journal article · DOI 10.1248/bpb.b20-00392Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro.
He W, Zhai X, Su J, Ye R, Zheng Y, Su S.
Pathogens · research-article; journal article · DOI 10.3390/pathogens8040258Germacrone cooperates with dexmedetomidine to alleviate high-fat diet-induced type 2 diabetes mellitus via upregulating AMPKα1 expression.
Sun Y, Li L, Wu J, Gong B, Liu H.
Exp Ther Med · retracted publication; research-article; journal article · DOI 10.3892/etm.2019.7990Germacrone alleviates collagen-induced arthritis via regulating Th1/Th2 balance and NF-κB activation.
Wang Z, Zhuo F, Chu P, Yang X, Zhao G.
Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2019.08.084Germacrone Derivatives as new Insecticidal and Acaricidal Compounds: A Structure-Activity Relationship.
Galisteo Pretel A, Pérez Del Pulgar H, Guerrero de León E, López-Pérez JL, Olmeda AS, Gonzalez-Coloma A, F Barrero A, Quílez Del Moral JF.
Molecules · research-article; journal article · DOI 10.3390/molecules24162898Improved self-assembled micelles based on supercritical fluid technology as a novel oral delivery system for enhancing germacrone oral bioavailability.
Hou X, Cao B, He Y, Guo T, Li Z, Liu Y, Zhang Y, Feng N.
Int J Pharm · journal article · DOI 10.1016/j.ijpharm.2019.118586Germacrone attenuates cerebral ischemia/reperfusion injury in rats via antioxidative and antiapoptotic mechanisms.
Wu T, Yin F, Kong H, Peng J.
J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/jcb.29210Germacrone reverses adriamycin resistance in human chronic myelogenous leukemia K562/ADM cells by suppressing MDR1 gene/P-glycoprotein expression.
Pan J, Miao D, Chen L.
Chem Biol Interact · journal article · DOI 10.1016/j.cbi.2018.04.012Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter.
Srivilai J, Waranuch N, Tangsumranjit A, Khorana N, Ingkaninan K.
Drug Deliv Transl Res · research support, non-u.s. gov't; journal article · DOI 10.1007/s13346-017-0447-7Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach.
Kong Q, Ma Y, Yu J, Chen X.
Sci Rep · research-article; journal article · DOI 10.1038/s41598-017-15812-9[Effect of germacrone in alleviating HUVECs damaged by H2O2-induced oxidative stress].
Chen QF, Wang G, Tang LQ, Yu XW, Li ZF, Yang XF.
Zhongguo Zhong Yao Za Zhi · journal article · DOI 10.19540/j.cnki.cjcmm.20170731.006Germacrone derivatives: synthesis, biological activity, molecular docking studies and molecular dynamics simulations.
Wu J, Feng Y, Han C, Huang W, Shen Z, Yang M, Chen W, Ye L.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.14832