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Publikationer som ChEBI hänvisar till för MDL-28170. Visa hela publikationsregistret

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Publications in the selection

29 hits

Bibliografisk träff 2024-10-31

Susceptibility of <i>Leishmania amazonensis</i> Axenic Amastigotes to the Calpain Inhibitor MDL28170.

Oliveira SSC, Marinho FA, Sangenito LS, Seabra SH, Menna-Barreto RF, d'Avila CM, Santos ALS, Branquinha MH.

Trop Med Infect Dis · research-article; journal article · DOI 10.3390/tropicalmed9110259

Bibliografisk träff 2024-09-24

Calpain-1 Up-Regulation Promotes Bleomycin-Induced Pulmonary Fibrosis by Activating Ferroptosis.

Wei S, Liu Y, Ran C, Li Y, Tang B, Lu M, Wang H.

Am J Pathol · journal article · DOI 10.1016/j.ajpath.2024.09.004

Bibliografisk träff 2023-07-06

Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway.

Lai R, Fang Q, Wu F, Pan S, Haque K, Sha SH.

Front Cell Neurosci · research-article; journal article · DOI 10.3389/fncel.2023.1199656

Bibliografisk träff 2023-03-17

Calpain inhibitor MDL28170 alleviates cerebral ischemia‑reperfusion injury by suppressing inflammation and autophagy in a rat model of cardiac arrest.

Wang WY, Shi JX, Chen MH, Zhuge XZ, Dai CG, Xie L.

Exp Ther Med · research-article; journal article · DOI 10.3892/etm.2023.11895

Bibliografisk träff 2022-02-16

Antileishmanial Efficacy of the Calpain Inhibitor MDL28170 in Combination with Amphotericin B.

Branquinha MH, Araújo PSS, Oliveira SSC, Sangenito LS, Gonçalves DS, Seabra SH, d'Avila-Levy CM, Santos ALS.

Trop Med Infect Dis · research-article; journal article · DOI 10.3390/tropicalmed7020029

Bibliografisk träff 2019-11-01

Investigation of the relationships between different enzymes and postmortem duck muscle tenderization.

He J, Deng F, Pan D, Zeng X.

Poult Sci · journal article · DOI 10.3382/ps/pez301

Bibliografisk träff 2019-10-15

Analysis of Resistance of Ebola Virus Glycoprotein-Driven Entry Against MDL28170, An Inhibitor of Cysteine Cathepsins.

Hoffmann M, Kaufmann SV, Fischer C, Maurer W, Moldenhauer AS, Pöhlmann S.

Pathogens · research-article; journal article · DOI 10.3390/pathogens8040192

Bibliografisk träff 2019-03-15

Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury.

Hu J, Chen L, Huang X, Wu K, Ding S, Wang W, Wang B, Smith C, Ren C, Ni H, ZhuGe Q, Yang J.

Stem Cell Res Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s13287-019-1210-4

Bibliografisk träff 2018-12-05

Local application of MDL28170-loaded PCL film improves functional recovery by preserving survival of motor neurons after traumatic spinal cord injury.

Shi D, He T, Tang W, Li H, Wang C, Zheng M, Hu J, Song X, Ding Y, Chen YY, Shen Y, Jin H, Wang LL.

Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2018.12.006

Bibliografisk träff 2018-05-04

Susceptibility of promastigotes and intracellular amastigotes from distinct Leishmania species to the calpain inhibitor MDL28170.

de Sousa Araújo PS, de Oliveira SSC, d'Avila-Levy CM, Dos Santos ALS, Branquinha MH.

Parasitol Res · journal article · DOI 10.1007/s00436-018-5894-7

Bibliografisk träff 2017-10-17

In vitro selection of Phytomonas serpens cells resistant to the calpain inhibitor MDL28170: alterations in fitness and expression of the major peptidases and efflux pumps.

Oliveira SSC, Gonçalves IC, Ennes-Vidal V, Lopes AHCS, Menna-Barreto RFS, D'Ávila-Levy CM, Santos ALS, Branquinha MH.

Parasitology · research support, non-u.s. gov't; journal article · DOI 10.1017/s0031182017001561

Bibliografisk träff 2017-06-27

The potent cell permeable calpain inhibitor MDL28170 affects the interaction of Leishmania amazonensis with macrophages and shows anti-amastigote activity.

Marinho FA, Sangenito LS, Oliveira SSC, De Arruda LB, D'Ávila-Levy CM, Santos ALS, Branquinha MH.

Parasitol Int · journal article · DOI 10.1016/j.parint.2017.06.010

Bibliografisk träff 2015-06-15

Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy.

Kharatmal SB, Singh JN, Sharma SS.

Neuropharmacology · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuropharm.2015.05.040

Bibliografisk träff 2012-04-01

Calpain inhibitor MDL 28170 protects against the Ca2+ paradox in rat hearts.

Bi SH, Jin ZX, Zhang JY, Chen T, Zhang SL, Yang Y, Duan WX, Yi DH, Zhou JJ, Ren J.

Clin Exp Pharmacol Physiol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1111/j.1440-1681.2012.05683.x

Bibliografisk träff 2012-01-12

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans.

Etheridge T, Oczypok EA, Lehmann S, Fields BD, Shephard F, Jacobson LA, Szewczyk NJ.

PLoS Genet · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pgen.1002471

Bibliografisk träff 2012-01-06

Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury.

Ma M, Li L, Wang X, Bull DL, Shofer FS, Meaney DF, Neumar RW.

J Neurotrauma · research-article; journal article; research support, n.i.h., extramural · DOI 10.1089/neu.2011.2060

Bibliografisk träff 2010-12-01

A pharmacological analysis of the neuroprotective efficacy of the brain- and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model.

Thompson SN, Carrico KM, Mustafa AG, Bains M, Hall ED.

J Neurotrauma · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1089/neu.2010.1474

Bibliografisk träff 2010-04-27

MDL-28170 has no analgesic effect on CCI induced neuropathic pain in mice.

Uçeyler N, Biko L, Sommer C.

Molecules · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/molecules15053038

Bibliografisk träff 2007-06-01

Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury.

Ai J, Liu E, Wang J, Chen Y, Yu J, Baker AJ.

J Neurotrauma · research support, non-u.s. gov't; journal article · DOI 10.1089/neu.2006.0224

Bibliografisk träff 2006-07-13

Antileishmanial activity of MDL 28170, a potent calpain inhibitor.

d'Avila-Levy CM, Marinho FA, Santos LO, Martins JL, Santos AL, Branquinha MH.

Int J Antimicrob Agents · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.ijantimicag.2006.03.021

Bibliografisk träff 2006-05-01

The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures.

Lopez-Picon FR, Kukko-Lukjanov TK, Holopainen IE.

Eur J Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1460-9568.2006.04793.x

Bibliografisk träff 2005-03-01

Calpain inhibitor MDL 28170 protects hypoxic-ischemic brain injury in neonatal rats by inhibition of both apoptosis and necrosis.

Kawamura M, Nakajima W, Ishida A, Ohmura A, Miura S, Takada G.

Brain Res · journal article · DOI 10.1016/j.brainres.2004.12.050

Bibliografisk träff 2004-09-01

Epimerization study of the L,L- and L,D-diastereoisomers of the calpain inhibitor MDL 28170 by capillary electrophoresis.

Chen TM, Jones HK.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2004.05.031

Bibliografisk träff 2004-07-01

The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia.

Kunz S, Niederberger E, Ehnert C, Coste O, Pfenninger A, Kruip J, Wendrich TM, Schmidtko A, Tegeder I, Geisslinger G.

Pain · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.pain.2004.04.031

Bibliografisk träff 2003-03-01

Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury.

Buki A, Farkas O, Doczi T, Povlishock JT.

J Neurotrauma · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1089/089771503321532842

Bibliografisk träff 2002-01-01

MDL 28170.

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Drugs R D · journal article · DOI 10.2165/00126839-200203020-00007

Bibliografisk träff 1998-05-01

Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia.

Li PA, Howlett W, He QP, Miyashita H, Siddiqui M, Shuaib A.

Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0304-3940(98)00266-3

Bibliografisk träff 1997-07-01

MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKC epsilon proteolysis in reperfused ferret hearts.

Urthaler F, Wolkowicz PE, Digerness SB, Harris KD, Walker AA.

Cardiovasc Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/s0008-6363(97)00099-0

Bibliografisk träff 1988-12-01

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain.

Mehdi S, Angelastro MR, Wiseman JS, Bey P.

Biochem Biophys Res Commun · comparative study; journal article · DOI 10.1016/s0006-291x(88)80989-6