Clinical potential of naloxegol in the management of opioid-induced bowel dysfunction.
Poulsen JL, Brock C, Olesen AE, Nilsson M, Drewes AM.
Clin Exp Gastroenterol · review-article; review; journal article · DOI 10.2147/ceg.s52097 PUBLICATION REGISTRY
Go to research.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för naloxegol. Visa hela publikationsregistret
A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publications in the selection
9 hitsNaloxegol for the treatment of opioid-induced constipation.
Tack J, Corsetti M.
Expert Rev Gastroenterol Hepatol · review; journal article · DOI 10.1586/17474124.2014.939629Naloxegol increases frequency of bowel movements and combats inadequate response to laxatives.
Holzer P.
Evid Based Med · comment; journal article · DOI 10.1136/ebmed-2014-110071Randomised clinical trial: the long-term safety and tolerability of naloxegol in patients with pain and opioid-induced constipation.
Webster L, Chey WD, Tack J, Lappalainen J, Diva U, Sostek M.
Aliment Pharmacol Ther · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1111/apt.12899The effects of renal impairment on the pharmacokinetics, safety, and tolerability of naloxegol.
Bui K, She F, Sostek M.
J Clin Pharmacol · controlled clinical trial; research support, non-u.s. gov't; multicenter study; journal article · DOI 10.1002/jcph.349The effects of mild or moderate hepatic impairment on the pharmacokinetics, safety, and tolerability of naloxegol.
Bui K, She F, Sostek M.
J Clin Pharmacol · controlled clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1002/jcph.348Naloxegol for opioid-induced constipation in patients with noncancer pain.
Chey WD, Webster L, Sostek M, Lappalainen J, Barker PN, Tack J.
N Engl J Med · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1056/nejmoa1310246Evaluation of the effect of Naloxegol on cardiac repolarization: a randomized, placebo- and positive-controlled crossover thorough QT/QTc study in healthy volunteers.
Gottfridsson C, Carlson G, Lappalainen J, Sostek M.
Clin Ther · research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1016/j.clinthera.2013.09.019A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation.
Webster L, Dhar S, Eldon M, Masuoka L, Lappalainen J, Sostek M.
Pain · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1016/j.pain.2013.04.024