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Publikationer som ChEBI hänvisar till för remikiren. Visa hela publikationsregistret

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Publications in the selection

25 hits

Bibliografisk träff 2015-09-25

Elucidation of the binding mechanism of renin using a wide array of computational techniques and biological assays.

Tzoupis H, Leonis G, Avramopoulos A, Reis H, Czyżnikowska Ż, Zerva S, Vergadou N, Peristeras LD, Papavasileiou KD, Alexis MN, Mavromoustakos T, Papadopoulos MG.

J Mol Graph Model · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jmgm.2015.09.015

Bibliografisk träff 2011-12-23

Aliskiren displays long-lasting interactions with human renin.

Gossas T, Vrang L, Henderson I, Sedig S, Sahlberg C, Lindström E, Danielson UH.

Naunyn Schmiedebergs Arch Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00210-011-0718-7

Bibliografisk träff 2000-05-01

Renal and systemic effects of continued treatment with renin inhibitor remikiren in hypertensive patients with normal and impaired renal function.

van Paassen P, de Zeeuw D, Navis G, de Jong PE.

Nephrol Dial Transplant · clinical trial; journal article · DOI 10.1093/ndt/15.5.637

Bibliografisk träff 1997-04-01

Dose effects of human renin in rats transgenic for human angiotensinogen.

Bohlender J, Ménard J, Luft FC, Ganten D.

Hypertension · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1161/01.hyp.29.4.1031

Bibliografisk träff 1996-06-01

Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system.

Himmelmann A, Bergbrant A, Svensson A, Hansson L, Aurell M.

Am J Hypertens · clinical trial; randomized controlled trial; journal article · DOI 10.1016/0895-7061(95)00340-1

Bibliografisk träff 1996-03-01

Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals.

Richter WF, Whitby BR, Chou RC.

Xenobiotica · comparative study; journal article · DOI 10.3109/00498259609046705

Bibliografisk träff 1996-03-01

Excretion and metabolism of remikiren, a potent orally active inhibitor of primate renin.

Jauch R, Schmid P, Fischli W, Meister W, Maurer R, Wendt G.

Xenobiotica · comparative study; journal article · DOI 10.3109/00498259609046708

Bibliografisk träff 1996-03-01

Pharmacokinetics of remikiren, a potent orally active inhibitor of human renin, in rat, dog and primates.

Coassolo P, Fischli W, Clozel JP, Chou RC.

Xenobiotica · comparative study; journal article · DOI 10.3109/00498259609046712

Bibliografisk träff 1996-03-01

Assessment of the role of the renin-angiotensin system in cardiac contractility utilizing the renin inhibitor remikiren.

van Kats JP, Sassen LM, Danser AH, Polak MP, Soei LK, Derkx FH, Schalekamp MA, Verdouw PD.

Br J Pharmacol · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.1996.tb15277.x

Bibliografisk träff 1996-02-01

Recombinant human renin produced in different expression systems: biochemical properties and 3D structure.

Mathews S, Döbeli H, Pruschy M, Bosser R, D'Arcy A, Oefner C, Zulauf M, Gentz R, Breu V, Matile H, Schlaeger J, Fischli W.

Protein Expr Purif · journal article · DOI 10.1006/prep.1996.0012

Bibliografisk träff 1995-07-01

Renal and systemic effects of the renin inhibitor remikiren in patients with essential hypertension.

van Paassen P, de Zeeuw D, de Jong PE.

J Cardiovasc Pharmacol · clinical trial; randomized controlled trial; journal article · DOI 10.1097/00005344-199507000-00007

Bibliografisk träff 1995-03-01

Responses to an orally active renin inhibitor, remikiren (Ro 42-5892), after controlled salt depletion in humans.

MacFadyen RJ, Jones CR, Doig JK, Birnbock H, Reid JL.

J Cardiovasc Pharmacol · clinical trial; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1097/00005344-199503000-00001

Bibliografisk träff 1995-03-01

Determination of the renin inhibitor Ro 42-5892 in human plasma by automated pre-column derivatization, reversed-phase high-performance liquid chromatographic separation and electrochemical detection after post-column irradiation.

Leube J, Fischer G.

J Chromatogr B Biomed Appl · journal article · DOI 10.1016/0378-4347(94)00542-d

Bibliografisk träff 1994-06-01

Vascular renin in the guinea pig. Suppression by the renin inhibitor remikiren.

Hilgers KF, Fischli W, Veelken R, Mann JF.

Hypertension · journal article · DOI 10.1161/01.hyp.23.6.861

Bibliografisk träff 1994-02-01

Time dependency of the antihypertensive efficacy of the new renin inhibitor Ro 42-5892.

Viskoper RJ, Charlon V, Laszt A, Yosefy C, Bock J, Landau M, Kobrin I.

J Hum Hypertens · clinical trial; randomized controlled trial; journal article

Bibliografisk träff 1993-12-01

Multiple dose pharmacokinetics and concentration effect relationship of the orally active renin inhibitor remikiren (Ro 42-5892) in hypertensive patients.

Weber C, Birnböck H, Leube J, Kobrin I, Kleinbloesem CH, Van Brummelen P.

Br J Clin Pharmacol · clinical trial; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1111/j.1365-2125.1993.tb00413.x

Bibliografisk träff 1993-11-01

Efficacy and tolerability of the renin inhibitor Ro 42-5892 in patients with hypertension.

Rongen GA, Lenders JW, Kleinbloesem CH, Weber C, Welker H, Fahrner E, Pozenel H, Woittiez AJ, Haug G, Buchmann MS.

Clin Pharmacol Ther · clinical trial; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1038/clpt.1993.189

Bibliografisk träff 1993-08-01

Effects of blocking the angiotensin II receptor, converting enzyme, and renin activity on the renal hemodynamics of normotensive guinea pigs.

el Amrani AI, Menard J, Gonzales MF, Michel JB.

J Cardiovasc Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/00005344-199308000-00010

Bibliografisk träff 1993-08-01

Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension.

van den Meiracker AH, Admiraal PJ, Derkx FH, Kleinbloesem C, Man in 't Veld AJ, van Brummelen P, Mulder P, Schalekamp MA.

J Hypertens · comparative study; clinical trial; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1097/00004872-199308000-00010

Bibliografisk träff 1993-05-01

Hemodynamics, biochemical effects, and pharmacokinetics of the renin inhibitor remikiren in healthy human subjects.

Kleinbloesem CH, Weber C, Fahrner E, Dellenbach M, Welker H, Schröter V, Belz GG.

Clin Pharmacol Ther · clinical trial; clinical trial, phase i; randomized controlled trial; journal article · DOI 10.1038/clpt.1993.74

Bibliografisk träff 1993-05-01

Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension.

Kobrin I, Viskoper RJ, Laszt A, Bock J, Weber C, Charlon V.

Am J Hypertens · clinical trial; randomized controlled trial; journal article · DOI 10.1093/ajh/6.5.349

Bibliografisk träff 1993-02-01

Renin inhibitors as an example of presumptive irrelevant positive findings in the Salmonella/mammalian microsome assay (Ames test).

Albertini S, Gocke E.

Mutat Res · journal article · DOI 10.1016/0165-1218(93)90002-u

Bibliografisk träff 1993-02-01

Discovery of remikiren as the first orally active renin inhibitor.

Clozel JP, Fischli W.

Arzneimittelforschung · review; journal article

Bibliografisk träff 1992-12-01

Neurohormonal and blood pressure responses to low-dose infusion of an orally active renin inhibitor, Ro 42-5892, in salt-replete men.

Doig JK, MacFadyen RJ, Meredith PA, Fischli W, Reid JL.

J Cardiovasc Pharmacol · clinical trial; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1097/00005344-199212000-00005

Bibliografisk träff 1992-02-01

A comparison of the effects of renin inhibition and angiotensin converting enzyme inhibition upon bradykinin potentiation.

Véniant M, Clozel JP, Fischli W.

J Hypertens · comparative study; journal article · DOI 10.1097/00004872-199202000-00008