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Publikationer som ChEBI hänvisar till för ZSTK-474. Visa hela publikationsregistret

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Publications in the selection

19 hits

Bibliografisk träff 2015-06-17

Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells.

Bertazza L, Barollo S, Radu CM, Cavedon E, Simioni P, Faggian D, Plebani M, Pelizzo MR, Rubin B, Boscaro M, Pezzani R, Mian C.

J Cell Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/jcmm.12612

Bibliografisk träff 2015-01-16

Basal expression of insulin-like growth factor 1 receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474.

Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S.

Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/cas.12582

Bibliografisk träff 2014-05-22

ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis.

Xue Z, Li W, Wang H, Huang B, Ge Z, Gu C, Liu Y, Zhang K, Yang J, Han R, Peng M, Li Y, Zhang D, Da Y, Yao Z, Zhang R.

J Mol Med (Berl) · research support, non-u.s. gov't; journal article · DOI 10.1007/s00109-014-1158-x

Bibliografisk träff 2014-05-13

The combination of RAF265, SB590885, ZSTK474 on thyroid cancer cell lines deeply impact on proliferation and MAPK and PI3K/Akt signaling pathways.

Barollo S, Bertazza L, Baldini E, Ulisse S, Cavedon E, Boscaro M, Pezzani R, Mian C.

Invest New Drugs · research support, non-u.s. gov't; journal article · DOI 10.1007/s10637-014-0108-3

Bibliografisk träff 2013-12-02

Dual targeting of glioblastoma multiforme with a proteasome inhibitor (Velcade) and a phosphatidylinositol 3-kinase inhibitor (ZSTK474).

Lin L, Gaut D, Hu K, Yan H, Yin D, Koeffler HP.

Int J Oncol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.3892/ijo.2013.2205

Bibliografisk träff 2013-10-01

Combination of the PI3K inhibitor ZSTK474 with a PSMA-targeted immunotoxin accelerates apoptosis and regression of prostate cancer.

Baiz D, Hassan S, Choi YA, Flores A, Karpova Y, Yancey D, Pullikuth A, Sui G, Sadelain M, Debinski W, Kulik G.

Neoplasia · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1593/neo.13986

Bibliografisk träff 2013-06-28

In vitro antimetastatic effect of phosphatidylinositol 3-kinase inhibitor ZSTK474 on prostate cancer PC3 cells.

Zhao W, Guo W, Zhou Q, Ma SN, Wang R, Qiu Y, Jin M, Duan HQ, Kong D.

Int J Mol Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/ijms140713577

Bibliografisk träff 2012-02-15

Inhibitory effects of ZSTK474, a phosphatidylinositol 3-kinase inhibitor, on adjuvant-induced arthritis in rats.

Haruta K, Mori S, Tamura N, Sasaki A, Nagamine M, Yaguchi S, Kamachi F, Enami J, Kobayashi S, Yamori T, Takasaki Y.

Inflamm Res · journal article · DOI 10.1007/s00011-012-0444-8

Bibliografisk träff 2011-11-14

ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo.

Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T.

Eur J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejca.2011.10.006

Bibliografisk träff 2011-10-12

ZSTK474, a PI3K inhibitor, suppresses proliferation and sensitizes human pancreatic adenocarcinoma cells to gemcitabine.

Duong HQ, Kim HJ, Kang HJ, Seong YS, Bae I.

Oncol Rep · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.3892/or.2011.1503

Bibliografisk träff 2011-04-04

Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.

Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi S, Enami J, Yamori T, Okayasu R.

Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1349-7006.2011.01916.x

Bibliografisk träff 2010-08-23

ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor identified using the JFCR39 drug discovery system.

Kong DX, Yamori T.

Acta Pharmacol Sin · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1038/aps.2010.150

Bibliografisk träff 2010-05-18

Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice.

Toyama S, Tamura N, Haruta K, Karakida T, Mori S, Watanabe T, Yamori T, Takasaki Y.

Arthritis Res Ther · research-article; journal article · DOI 10.1186/ar3019

Bibliografisk träff 2010-02-01

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL.

Nat Chem Biol · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1038/nchembio.293

Bibliografisk träff 2009-02-01

Effect of ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor, on DNA-dependent protein kinase.

Kong D, Yaguchi S, Yamori T.

Biol Pharm Bull · research support, non-u.s. gov't; journal article · DOI 10.1248/bpb.32.297

Bibliografisk träff 2009-01-12

Antiangiogenic effect of ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor.

Kong D, Okamura M, Yoshimi H, Yamori T.

Eur J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejca.2008.12.007

Bibliografisk träff 2008-12-16

Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest.

Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2008.12.015

Bibliografisk träff 2007-08-16

ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.

Kong D, Yamori T.

Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1349-7006.2007.00580.x

Bibliografisk träff 2006-04-01

Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor.

Yaguchi S, Fukui Y, Koshimizu I, Yoshimi H, Matsuno T, Gouda H, Hirono S, Yamazaki K, Yamori T.

J Natl Cancer Inst · research support, non-u.s. gov't; journal article · DOI 10.1093/jnci/djj133