p38 MAP Kinase Inhibition Reduces Propionibacterium acnes-Induced Inflammation in Vitro.
Li WH, Zhang L, Lyte P, Rodriguez K, Cavender D, Southall MD.
Dermatol Ther (Heidelb) · research-article; journal article · DOI 10.1007/s13555-015-0072-7 PUBLICATION REGISTRY
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6 hitsSignal transduction inhibitors in treatment of myelodysplastic syndromes.
Bachegowda L, Gligich O, Mantzaris I, Schinke C, Wyville D, Carrillo T, Braunschweig I, Steidl U, Verma A.
J Hematol Oncol · review-article; review; journal article · DOI 10.1186/1756-8722-6-50Randomized, dose-escalation study of the p38α MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome.
Sokol L, Cripe L, Kantarjian H, Sekeres MA, Parmar S, Greenberg P, Goldberg SL, Bhushan V, Shammo J, Hohl R, Verma A, Garcia-Manero G, Li YP, Lowe A, Zhu J, List AF.
Leukemia · letter; clinical trial, phase ii; research support, non-u.s. gov't; clinical trial, phase i; randomized controlled trial · DOI 10.1038/leu.2012.264X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors.
Azevedo R, van Zeeland M, Raaijmakers H, Kazemier B, de Vlieg J, Oubrie A.
Acta Crystallogr D Biol Crystallogr · comparative study; journal article · DOI 10.1107/s090744491201997xNovel p38α mitogen-activated protein kinase inhibitor shows analgesic efficacy in acute postsurgical dental pain.
Tong SE, Daniels SE, Black P, Chang S, Protter A, Desjardins PJ.
J Clin Pharmacol · multicenter study; randomized controlled trial; journal article · DOI 10.1177/0091270011405496Fluorophore labeling of the glycine-rich loop as a method of identifying inhibitors that bind to active and inactive kinase conformations.
Simard JR, Getlik M, Grütter C, Schneider R, Wulfert S, Rauh D.
J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/ja908083e