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Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för lumacaftor. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

13 hits

Bibliografisk träff 2016-01-13

Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor).

Matthes E, Goepp J, Carlile GW, Luo Y, Dejgaard K, Billet A, Robert R, Thomas DY, Hanrahan JW.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.13365

Bibliografisk träff 2015-12-30

Lumacaftor-ivacaftor (Orkambi) for cystic fibrosis: behind the 'breakthrough'.

Mayer M.

Evid Based Med · journal article · DOI 10.1136/ebmed-2015-110325

Bibliografisk träff 2015-12-09

Lumacaftor alone and combined with ivacaftor: preclinical and clinical trial experience of F508del CFTR correction.

Brewington JJ, McPhail GL, Clancy JP.

Expert Rev Respir Med · research support, non-u.s. gov't; journal article · DOI 10.1586/17476348.2016.1122527

Bibliografisk träff 2015-11-14

Searching for a cure for cystic fibrosis. A 25-year quest in a nutshell.

Bosch B, De Boeck K.

Eur J Pediatr · research support, non-u.s. gov't; review; journal article · DOI 10.1007/s00431-015-2664-8

Bibliografisk träff 2015-10-27

Response to: 'Lumacaftor/ivacaftor for patients homozygous for Phe508del-CFTR: should we curb our enthusiasm?' by Jones and Barry.

Elborn JS, Ramsey B, Wainwright C, Boyle M.

Thorax · letter; comment · DOI 10.1136/thoraxjnl-2015-207611

Bibliografisk träff 2015-10-01

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.

Wainwright CE, Elborn JS, Ramsey BW.

N Engl J Med · letter; comment · DOI 10.1056/nejmc1510466

Bibliografisk träff 2015-10-01

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.

Rehman A, Baloch NU, Janahi IA.

N Engl J Med · letter; comment · DOI 10.1056/nejmc1510466

Bibliografisk träff 2015-09-28

Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects.

Kuk K, Taylor-Cousar JL.

Ther Adv Respir Dis · research support, non-u.s. gov't; review; journal article; research support, n.i.h., extramural · DOI 10.1177/1753465815601934

Bibliografisk träff 2015-09-01

Pharmaceutical Approval Update.

Gohil K.

P T · other; journal article

Bibliografisk träff 2015-07-01

Lumacaftor/ivacaftor for patients homozygous for Phe508del-CFTR: should we curb our enthusiasm?

Jones AM, Barry PJ.

Thorax · editorial · DOI 10.1136/thoraxjnl-2015-207369

Bibliografisk träff 2015-05-17

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.

Wainwright CE, Elborn JS, Ramsey BW, Marigowda G, Huang X, Cipolli M, Colombo C, Davies JC, De Boeck K, Flume PA, Konstan MW, McColley SA, McCoy K, McKone EF, Munck A, Ratjen F, Rowe SM, Waltz D, Boyle MP, TRAFFIC Study Group, TRANSPORT Study Group.

N Engl J Med · clinical trial, phase iii; research support, non-u.s. gov't; research-article; multicenter study; randomized controlled trial; journal article; research support, n.i.h., extramural · DOI 10.1056/nejmoa1409547

Bibliografisk träff 2014-06-24

A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial.

Boyle MP, Bell SC, Konstan MW, McColley SA, Rowe SM, Rietschel E, Huang X, Waltz D, Patel NR, Rodman D, VX09-809-102 study group.

Lancet Respir Med · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article; research support, n.i.h., extramural · DOI 10.1016/s2213-2600(14)70132-8

Bibliografisk träff 2014-04-26

Direct interaction of a CFTR potentiator and a CFTR corrector with phospholipid bilayers.

Baroni D, Zegarra-Moran O, Svensson A, Moran O.

Eur Biophys J · research support, non-u.s. gov't; journal article · DOI 10.1007/s00249-014-0956-y