The Potential Contribution of microRNAs in Anti-cancer Effects of Aurora Kinase Inhibitor (AZD1152-HQPA).
Zekri A, Mesbahi Y, Boustanipour E, Sadr Z, Ghaffari SH.
J Mol Neurosci · journal article · DOI 10.1007/s12031-018-1118-y PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för AZD-1152. Visa hela publikationsregistret
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7 hitsPreclinical evaluation of the Aurora kinase inhibitors AMG 900, AZD1152-HQPA, and MK-5108 on SW-872 and 93T449 human liposarcoma cells.
Noronha S, Alt LAC, Scimeca TE, Zarou O, Obrzut J, Zanotti B, Hayward EA, Pillai A, Mathur S, Rojas J, Salamah R, Chandar N, Fay MJ.
In Vitro Cell Dev Biol Anim · journal article · DOI 10.1007/s11626-017-0208-4Reactive oxygen species generation and increase in mitochondrial copy number: new insight into the potential mechanism of cytotoxicity induced by aurora kinase inhibitor, AZD1152-HQPA.
Zekri A, Mesbahi Y, Ghanizadeh-Vesali S, Alimoghaddam K, Ghavamzadeh A, Ghaffari SH.
Anticancer Drugs · research support, non-u.s. gov't; journal article · DOI 10.1097/cad.0000000000000523Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA.
Zekri A, Ghaffari SH, Yaghmaie M, Estiar MA, Alimoghaddam K, Modarressi MH, Ghavamzadeh A.
Mol Neurobiol · research support, non-u.s. gov't; journal article · DOI 10.1007/s12035-015-9139-9AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy.
Zekri A, Ghaffari SH, Ghanizadeh-Vesali S, Yaghmaie M, Salmaninejad A, Alimoghaddam K, Modarressi MH, Ghavamzadeh A.
Tumour Biol · research support, non-u.s. gov't; journal article · DOI 10.1007/s13277-014-2664-8The FLT3 internal tandem duplication mutation is a secondary target of the aurora B kinase inhibitor AZD1152-HQPA in acute myelogenous leukemia cells.
Grundy M, Seedhouse C, Shang S, Richardson J, Russell N, Pallis M.
Mol Cancer Ther · research support, non-u.s. gov't; journal article · DOI 10.1158/1535-7163.mct-09-1144Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts.
Walsby E, Walsh V, Pepper C, Burnett A, Mills K.
Haematologica · research support, non-u.s. gov't; journal article · DOI 10.3324/haematol.12148