The Effect of Aurora Kinase Inhibitor on Adhesion and Migration in Human Breast Cancer Cells and Clinical Implications.
Zhao H, Owen S, Davies EL, Jiang WG, Martin TA.
World J Oncol · research-article; journal article · DOI 10.14740/wjon1062w PUBLICATION REGISTRY
Go to research.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för ZM447439. Visa hela publikationsregistret
A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publications in the selection
16 hitsCentmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.
Mäki-Jouppila JH, Laine LJ, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, Halonen P, Lindqvist A, Kallio L, Poso A, Kallio MJ.
Mol Cancer Ther · research support, non-u.s. gov't; journal article · DOI 10.1158/1535-7163.mct-13-0685A comparative study of the aneugenic and polyploidy-inducing effects of fisetin and two model Aurora kinase inhibitors.
Gollapudi P, Hasegawa LS, Eastmond DA.
Mutat Res Genet Toxicol Environ Mutagen · comparative study; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.mrgentox.2014.03.004The dual Aurora kinase inhibitor ZM447439 prevents anaplastic thyroid cancer cell growth and tumorigenicity.
Baldini E, Tuccilli C, Prinzi N, Sorrenti S, Antonelli A, Gnessi L, Catania A, Moretti C, Mocini R, Carbotta G, Morrone S, Persechino S, Redler A, De Antoni E, D' Armiento M, Ulisse S.
J Biol Regul Homeost Agents · research support, non-u.s. gov't; journal articleSpatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates cell spreading through FHOD1.
Floyd S, Whiffin N, Gavilan MP, Kutscheidt S, De Luca M, Marcozzi C, Min M, Watkins J, Chung K, Fackler OT, Lindon C.
J Cell Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1242/jcs.123232Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.
Kasuboski JM, Bader JR, Vaughan PS, Tauhata SB, Winding M, Morrissey MA, Joyce MV, Boggess W, Vos L, Chan GK, Hinchcliffe EH, Vaughan KT.
Mol Biol Cell · research-article; journal article · DOI 10.1091/mbc.e11-03-0213ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.
Zhang L, Zhang S.
J Obstet Gynaecol Res · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1447-0756.2010.01414.xPhosphorylation of histone H3 serine 10 in early mouse embryos: active phosphorylation at late S phase and differential effects of ZM447439 on first two embryonic mitoses.
Teperek-Tkacz M, Meglicki M, Pasternak M, Kubiak JZ, Borsuk E.
Cell Cycle · research support, non-u.s. gov't; journal article · DOI 10.4161/cc.9.23.14023ZM447439, a novel promising aurora kinase inhibitor, provokes antiproliferative and proapoptotic effects alone and in combination with bio- and chemotherapeutic agents in gastroenteropancreatic neuroendocrine tumor cell lines.
Georgieva I, Koychev D, Wang Y, Holstein J, Hopfenmüller W, Zeitz M, Grabowski P.
Neuroendocrinology · research support, non-u.s. gov't; journal article · DOI 10.1159/000258705Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Li M, Jung A, Ganswindt U, Marini P, Friedl A, Daniel PT, Lauber K, Jendrossek V, Belka C.
Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2009.08.011[Inhibitors of aurora kinases].
Pinel S, Barbault-Foucher S, Lott-Desroches MC, Astier A.
Ann Pharm Fr · review; journal article · DOI 10.1016/j.pharma.2008.12.005Molecular basis of drug resistance in aurora kinases.
Girdler F, Sessa F, Patercoli S, Villa F, Musacchio A, Taylor S.
Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.chembiol.2008.04.013Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts.
Walsby E, Walsh V, Pepper C, Burnett A, Mills K.
Haematologica · research support, non-u.s. gov't; journal article · DOI 10.3324/haematol.12148ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensional culture.
Long ZJ, Xu J, Yan M, Zhang JG, Guan Z, Xu DZ, Wang XR, Yao J, Zheng FM, Chu GL, Cao JX, Zeng YX, Liu Q.
Cell Cycle · comparative study; research support, non-u.s. gov't; journal article · DOI 10.4161/cc.7.10.5949Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts.
Gadea BB, Ruderman JV.
Mol Biol Cell · research support, u.s. gov't, p.h.s.; research-article; journal article; research support, n.i.h., extramural · DOI 10.1091/mbc.e04-10-0891Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.
J Cell Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1083/jcb.200208091